Changes in Inflammatory Biomarkers in Patients with Schizophrenia: A 3-Year Retrospective Study
Zhu X, Li R, Zhu Y, Zhou J, Huang J, Zhou Y, Tong J, Zhang P, Luo X, Chen S, Li Y, Tian B, Tan S, Wang Z, Han X, Tian L, Li C, Tan Y. Changes in Inflammatory Biomarkers in Patients with Schizophrenia: A 3-Year Retrospective Study. Neuropsychiatric Disease And Treatment 2023, 19: 1597-1604. PMID: 37465565, PMCID: PMC10350427, DOI: 10.2147/ndt.s411028.Peer-Reviewed Original ResearchSystemic immune-inflammation indexMonocyte/lymphocyte ratioNeutrophil/lymphocyte ratioPlatelet/lymphocyte ratioLymphocyte ratioLYM countSex-matched healthy participantsComplete blood count dataContinuous antipsychotic treatmentPathophysiology of schizophreniaImmune system activationLinear mixed modelsBlood count dataImpact of ageInflammatory hypothesisInflammatory biomarkersNeutrophil countAntipsychotic treatmentInflammatory stateRetrospective studyHealthy controlsSystem activationPatientsFull courseSchizophrenia diagnosis