2010
Examining antidepressant drug response by smoking status: why is it important and how often is it done?
Weinberger AH, McKee SA, Picciotto MR, Mazure CM. Examining antidepressant drug response by smoking status: why is it important and how often is it done? Journal Of Psychopharmacology 2010, 25: 1269-1276. PMID: 21169392, PMCID: PMC3256572, DOI: 10.1177/0269881110389347.Peer-Reviewed Original ResearchConceptsSmoking statusImpact of smokingEffect of smokingNeurobiology of depressionAntidepressant treatment outcomeAntidepressant drug responsePharmacological intervention studiesPharmacological trialsClinical trialsTreatment outcomesMEDLINE searchNicotine dependenceSmokingTargeted treatmentIntervention studiesTreatment studiesDrug responseDepressionOutcomesTreatment researchTrialsStatusTreatmentAntidepressantsPharmacotherapyInclusion of Women and Gender-Specific Analyses in Randomized Clinical Trials of Treatments for Depression
Weinberger AH, McKee SA, Mazure CM. Inclusion of Women and Gender-Specific Analyses in Randomized Clinical Trials of Treatments for Depression. Journal Of Women's Health 2010, 19: 1727-1732. PMID: 20799923, PMCID: PMC2936499, DOI: 10.1089/jwh.2009.1784.Peer-Reviewed Original ResearchConceptsRecent randomized clinical trialsRandomized clinical trialsClinical trialsGender-specific analysisDepression treatmentHealth (NIH) Revitalization ActCost of depressionInterventional studyInclusion of womenHigh prevalenceTreatment responseMEDLINE searchTreatment efficacyGender differencesPossible gender differencesDepression researchTrialsWomenDepressionNational InstituteRevitalization ActTreatmentFemale participantsOutcomesGender
2009
The Inclusion of Women and Minorities in Smoking Cessation Clinical Trials: A Systematic Review
Dickerson DL, Leeman RF, Mazure CM, O'Malley SS. The Inclusion of Women and Minorities in Smoking Cessation Clinical Trials: A Systematic Review. American Journal On Addictions 2009, 18: 21-28. PMID: 19219662, PMCID: PMC2764011, DOI: 10.1080/10550490802408522.Peer-Reviewed Original Research
1995
Desipramine Treatment of Major Depression in Patients Over 75 Years of Age
Nelson J, Mazure C, Jatlow P. Desipramine Treatment of Major Depression in Patients Over 75 Years of Age. Journal Of Clinical Psychopharmacology 1995, 15: 99-105.. PMID: 7782495, DOI: 10.1097/00004714-199504000-00004.Peer-Reviewed Original ResearchConceptsYounger patientsYears of ageElderly patientsMajor depressionDesipramine concentrationsDrug treatmentPatient trialsAdverse reaction rateMore effective drug treatmentsEffective drug treatmentUnipolar major depressionDesipramine treatmentDepressed patientsComparable dosesPatientsSide effectsResponse rateSimilar durationTrialsSecond trialTreatmentLower ratesBloodDepressionAge
1990
Value of the DST for predicting response of patients with major depression to hospitalization and desipramine
Nelson JC, Mazure CM, Jatlow PI. Value of the DST for predicting response of patients with major depression to hospitalization and desipramine. American Journal Of Psychiatry 1990, 147: 1488-1492. PMID: 2221161, DOI: 10.1176/ajp.147.11.1488.Peer-Reviewed Original ResearchConceptsDexamethasone suppression testResponse of patientsMajor depressionNegative dexamethasone suppression testPositive dexamethasone suppression testWeeks of hospitalizationNonpsychotic major depressionPlasma levelsSuppression testRate of responseAntidepressant drugsDrug treatmentPatientsHospitalizationDesipraminePrior reportsDepressionResponsePrior studiesPlaceboFindingsTrialsWeeksDoes melancholia predict response in major depression?
Nelson J, Mazure C, Jatlow P. Does melancholia predict response in major depression? Journal Of Affective Disorders 1990, 18: 157-165. PMID: 2139060, DOI: 10.1016/0165-0327(90)90032-4.Peer-Reviewed Original Research
1989
The Yale-Brown Obsessive Compulsive Scale: II. Validity
Goodman WK, Price LH, Rasmussen SA, Mazure C, Delgado P, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale: II. Validity. JAMA Psychiatry 1989, 46: 1012-1016. PMID: 2510699, DOI: 10.1001/archpsyc.1989.01810110054008.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleObsessive Compulsive ScaleYale-Brown scaleScale scoreCompulsive ScaleSecondary depressive symptomsPlacebo-controlled trialCohort of patientsDrug-induced changesObsessive-compulsive disorder symptom severityMeasures of depressionDrug trialsOutcome measuresDisorder symptom severityDepressive symptomsObsessive-compulsive disorder symptomsSymptom severityPatientsBaseline ratingsDisordersDisorder symptomsValid instrumentSymptomsTrials
1988
Antidepressant activity of 2‐hydroxydesipramine
Nelson J, Mazure C, Jatlow P. Antidepressant activity of 2‐hydroxydesipramine. Clinical Pharmacology & Therapeutics 1988, 44: 283-288. PMID: 3416551, DOI: 10.1038/clpt.1988.151.Peer-Reviewed Original ResearchConceptsPlasma levelsOH-DMIAntidepressant activityDSM-III major depressionDMI levelsSteady-state plasma levelsWeeks of hospitalizationDrug plasma levelsFixed-dose protocolTotal drug levelsMajor depressionDrug levelsParent drugMeasure of responseTrialsResponsePrior studiesHospitalizationLevelsMedicationsPatientsInpatientsNonpsychoticDoseWeeks