2023
Comparative Analysis of Mortality and Amputation Rates in Patients Undergoing Atherectomy for Infra-Popliteal Peripheral Arterial Disease: Insight From the VQI.
Jamil Y, Nanna M, Chaar C, Mena-Hurtado C, Attaran R. Comparative Analysis of Mortality and Amputation Rates in Patients Undergoing Atherectomy for Infra-Popliteal Peripheral Arterial Disease: Insight From the VQI. Journal Of Endovascular Therapy 2023, 15266028231208895. PMID: 37919968, DOI: 10.1177/15266028231208895.Peer-Reviewed Original ResearchPlain old balloon angioplastyMajor adverse limb eventsLower extremity revascularizationPeripheral arterial diseaseLong-term outcomesArterial diseaseClinical outcomesVascular Quality Initiative databaseImproved long-term outcomesPropensity scoreAdverse limb eventsDifferent endovascular modalitiesInfra-popliteal diseaseLong-term amputationLow perioperative complicationsMultivariable logistic regressionImproved clinical outcomesLower ratesAdjunctive atherectomyMajor amputationAmputation ratePerioperative complicationsRenal complicationsBaseline characteristicsEndovascular modalitiesDrug‐Coated Balloon and Drug‐Eluting Stent Safety in Patients With Femoropopliteal and Severe Chronic Kidney Disease
Hanna J, Smolderen K, Castro‐Dominguez Y, Romain G, Lee M, Turner J, Mena‐Hurtado C. Drug‐Coated Balloon and Drug‐Eluting Stent Safety in Patients With Femoropopliteal and Severe Chronic Kidney Disease. Journal Of The American Heart Association 2023, 12: e028622. PMID: 36974774, PMCID: PMC10122876, DOI: 10.1161/jaha.122.028622.Peer-Reviewed Original ResearchConceptsEarly-stage chronic kidney diseaseChronic kidney diseaseBare metal stentsDrug-eluting stentsDrug-coated balloonsMortality riskAmputation riskKidney diseaseSevere chronic kidney diseaseMajor amputation riskPlain balloon angioplastyDrug-Coated BalloonAmputation outcomesCKD statusAmputation rateCause mortalityBackground PatientsAdjusted analysisBalloon angioplastyFemoropopliteal interventionsDES useBMS useRegistry dataDisease trialsPatients
2022
The Impact of Clinical Follow-Up After Revascularization on the Outcomes of Patients with Chronic Limb Threatening Ischemia
Kiwan G, Mohamedali A, Kim T, Zhuo H, Zhang Y, Mena-Hurtado C, Mojibian H, Cardella J, Ochoa Chaar CI. The Impact of Clinical Follow-Up After Revascularization on the Outcomes of Patients with Chronic Limb Threatening Ischemia. Annals Of Vascular Surgery 2022, 86: 286-294. PMID: 35803459, DOI: 10.1016/j.avsg.2022.05.043.Peer-Reviewed Original ResearchConceptsLower extremity revascularizationReintervention rateCompliant patientsNoncompliant patientsLimb amputationSingle-center retrospective chart reviewChronic limb threatening ischemiaOverall reintervention rateOutcomes of patientsLimb threatening ischemiaMajor amputation ratePeripheral arterial diseaseRetrospective chart reviewLong-term outcomesMajor limb amputationImpact of ClinicalSignificant differencesMajor amputationAmputation ratePerioperative outcomesBaseline characteristicsChart reviewExtremity revascularizationIschemia patientsMore reinterventionsVariability in 30-day major amputation rates following endovascular peripheral vascular intervention for critical limb ischemia
Provance JB, Spertus JA, Jones PG, Hoffman MA, Bunte MC, Vogel TR, Mena-Hurtado C, Smolderen KG. Variability in 30-day major amputation rates following endovascular peripheral vascular intervention for critical limb ischemia. Vascular Medicine 2022, 27: 350-357. PMID: 35603755, DOI: 10.1177/1358863x221098097.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsCritical limb ischemiaMedian risk ratioEndovascular peripheral vascular interventionsMajor amputation ratePatient-level factorsAmputation ratePVI procedureLimb ischemiaRisk ratioVascular interventionsNational electronic health record databaseElectronic health record databasePredictors of amputationRate of amputationMixed effects Poisson regression modelHealth record databaseEffects Poisson regression modelPoisson regression modelsCLI carePrevious amputationClinical factorsCLI treatmentBlack raceDiagnosis codes
2020
Seasonal variation in U.S. hospitalizations for chronic limb‐threatening ischemia
Altin SE, Kim YG, Aronow HD, Armstrong EJ, Goldsweig AM, Dardik A, Lanksy AJ, Mena‐Hurtado C, Abbott JD. Seasonal variation in U.S. hospitalizations for chronic limb‐threatening ischemia. Catheterization And Cardiovascular Interventions 2020, 96: 1473-1480. PMID: 32902126, DOI: 10.1002/ccd.29261.Peer-Reviewed Original ResearchConceptsCritical limb-threatening ischemiaLimb-threatening ischemiaNational Inpatient SampleMinor amputationChronic limb-threatening ischemiaUtilization Project National Inpatient SampleProvider education effortsCoronary artery diseaseAmputation rateHospital mortalityImportant comorbidityDiabetic statusOverall cohortSecondary outcomesArtery diseaseHospital admissionPrimary outcomeHospitalization incidenceU.S. hospitalizationsDiagnosis codesInpatient SampleHigher oddsAdmission seasonHealthcare costsMortality rateUtility of Intravascular Ultrasound in Peripheral Vascular Interventions: Systematic Review and Meta-Analysis
Sheikh AB, Anantha-Narayanan M, Smolderen KG, Jelani QU, Nagpal S, Schneider M, Llanos F, Ionescu C, Regan C, Attaran R, Altin SE, Mena-Hurtado C. Utility of Intravascular Ultrasound in Peripheral Vascular Interventions: Systematic Review and Meta-Analysis. Vascular And Endovascular Surgery 2020, 54: 413-422. PMID: 32338163, DOI: 10.1177/1538574420920998.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsPeriprocedural adverse eventsVascular complicationsAdverse eventsIntravascular ultrasoundPrimary patencyCause mortalityTechnical successMyocardial infarctionObservational studyVascular interventionsEnd pointSimilar patency ratesSimilar primary patencyPrimary end pointRate of reinterventionSecondary end pointsPeripheral arterial diseaseImproved clinical outcomesIVUS groupAmputation rateArterial diseaseClinical outcomesPatency ratesLower risk
2016
Impact of Glycoprotein IIb/IIIa Inhibitors Use on Outcomes After Lower Extremity Endovascular Interventions From Nationwide Inpatient Sample (2006–2011)
Arora S, Panaich SS, Patel N, Patel NJ, Lahewala S, Thakkar B, Savani C, Jhamnani S, Singh V, Patel N, Patel S, Sonani R, Patel A, Tripathi B, Deshmukh A, Chothani A, Patel J, Bhatt P, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Mena CI, Schreiber T, Grines C, Cleman M, Forrest JK, Badheka AO. Impact of Glycoprotein IIb/IIIa Inhibitors Use on Outcomes After Lower Extremity Endovascular Interventions From Nationwide Inpatient Sample (2006–2011). Catheterization And Cardiovascular Interventions 2016, 88: 605-616. PMID: 26914274, DOI: 10.1002/ccd.26452.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmputation, SurgicalCross-Sectional StudiesDatabases, FactualDrug CostsEndovascular ProceduresFemaleHospital CostsHospital MortalityHumansLimb SalvageLogistic ModelsLower ExtremityMaleMiddle AgedMultivariate AnalysisOdds RatioPeripheral Arterial DiseasePlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexPropensity ScoreRisk FactorsTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsGlycoprotein IIb/IIIa inhibitorsPeripheral endovascular interventionsHospital mortalityHospitalization costsEndovascular interventionGPI useAmputation rateUtilization Project Nationwide Inpatient Sample databaseTwo-level hierarchical multivariateIIb/IIIa inhibitorsNationwide Inpatient Sample databaseLower amputation ratesPaucity of dataHospital outcomesPostprocedural complicationsSecondary outcomesPropensity matchingStudy cohortHealthcare costsICD-9Multivariate analysisStudy outcomesSample databaseMortalityHierarchical multivariate
2015
Intravascular Ultrasound in Lower Extremity Peripheral Vascular Interventions
Panaich SS, Arora S, Patel N, Patel NJ, Savani C, Patel A, Thakkar B, Singh V, Patel S, Patel N, Agnihotri K, Bhatt P, Deshmukh A, Gupta V, Attaran RR, Mena CI, Grines CL, Cleman M, Forrest JK, Badheka AO. Intravascular Ultrasound in Lower Extremity Peripheral Vascular Interventions. Journal Of Endovascular Therapy 2015, 23: 65-75. PMID: 26637836, DOI: 10.1177/1526602815620780.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmputation, SurgicalChi-Square DistributionCost-Benefit AnalysisDatabases, FactualEndovascular ProceduresFemaleHospital CostsHospital MortalityHumansLimb SalvageLinear ModelsLower ExtremityMaleMiddle AgedMultivariate AnalysisOdds RatioPeripheral Vascular DiseasesPractice Patterns, Physicians'Risk FactorsTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesYoung AdultConceptsLower limb endovascular interventionsPostprocedural complicationsHospitalization costsEndovascular interventionHospital mortalityAmputation rateOdds ratioNonsignificant increaseUtilization Project Nationwide Inpatient Sample databaseTwo-level hierarchical multivariateICD-9 procedure codesNationwide Inpatient Sample databasePeripheral vascular proceduresCo-primary outcomesLower amputation ratesPeripheral vascular interventionsPeripheral endovascular interventionsConfidence intervalsIVUS useIVUS utilizationSecondary outcomesStudy cohortVascular proceduresVascular interventionsHealthcare costsImpact of Hospital Volume on Outcomes of Lower Extremity Endovascular Interventions (Insights from the Nationwide Inpatient Sample [2006 to 2011])
Arora S, Panaich SS, Patel N, Patel N, Lahewala S, Solanki S, Patel P, Patel A, Manvar S, Savani C, Tripathi B, Thakkar B, Jhamnani S, Singh V, Patel S, Patel J, Bhimani R, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Grines C, Mena CI, Cleman M, Forrest J, Badheka AO. Impact of Hospital Volume on Outcomes of Lower Extremity Endovascular Interventions (Insights from the Nationwide Inpatient Sample [2006 to 2011]). The American Journal Of Cardiology 2015, 116: 791-800. PMID: 26100585, DOI: 10.1016/j.amjcard.2015.05.050.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overEndovascular ProceduresFemaleFollow-Up StudiesHospital CostsHospital MortalityHospitals, High-VolumeHospitals, Low-VolumeHumansIncidenceInpatientsLower ExtremityMaleMiddle AgedPeripheral Arterial DiseasePostoperative ComplicationsPostoperative PeriodPrognosisRegistriesRetrospective StudiesUnited StatesYoung AdultConceptsPeripheral endovascular interventionsHospitalization costsEndovascular interventionInhospital mortalityAmputation rateHospital volumePrimary outcomeCharlson co-morbidity index scoreUtilization Project Nationwide Inpatient Sample databaseLower Extremity Endovascular InterventionsTwo-level hierarchical multivariateNationwide Inpatient Sample databaseHospital volume quartilesCo-morbidity statusHospital procedural volumeLower amputation ratesAppropriate International ClassificationHigh-volume centersAnnual institutional volumeWeekend admissionSecondary outcomesPostprocedural complicationsStudy cohortNinth RevisionVolume centersComparison of Inhospital Outcomes and Hospitalization Costs of Peripheral Angioplasty and Endovascular Stenting
Panaich SS, Arora S, Patel N, Patel NJ, Lahewala S, Solanki S, Manvar S, Savani C, Jhamnani S, Singh V, Patel SV, Thakkar B, Patel A, Deshmukh A, Chothani A, Bhatt P, Savani GT, Patel J, Mavani K, Bhimani R, Tripathi B, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Grines C, Mena CI, Cleman M, Forrest JK, Badheka AO. Comparison of Inhospital Outcomes and Hospitalization Costs of Peripheral Angioplasty and Endovascular Stenting. The American Journal Of Cardiology 2015, 116: 634-641. PMID: 26096999, DOI: 10.1016/j.amjcard.2015.05.031.Peer-Reviewed Original ResearchConceptsLower amputation ratesInhospital mortalityPostprocedural complicationsHospitalization costsEndovascular stentingAmputation rateUtilization Project Nationwide Inpatient Sample databaseTwo-level hierarchical multivariateNationwide Inpatient Sample databaseComposite end pointPeripheral arterial diseaseHigher hospitalization costsAppropriate International ClassificationPeripheral endovascular interventionsInhospital outcomesSecondary outcomesPeripheral angioplastyPrimary outcomeArterial diseaseClinical outcomesStudy cohortNinth RevisionPatency ratesEndovascular interventionAngioplasty