2021
Twelve-Month Retention in Opioid Agonist Treatment for Opioid Use Disorder Among Patients With and Without HIV
Wyse JJ, McGinnis KA, Edelman EJ, Gordon AJ, Manhapra A, Fiellin DA, Moore BA, Korthuis PT, Kennedy AJ, Oldfield BJ, Gaither JR, Gordon KS, Skanderson M, Barry DT, Bryant K, Crystal S, Justice AC, Kraemer KL. Twelve-Month Retention in Opioid Agonist Treatment for Opioid Use Disorder Among Patients With and Without HIV. AIDS And Behavior 2021, 26: 975-985. PMID: 34495424, PMCID: PMC8840957, DOI: 10.1007/s10461-021-03452-0.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidCohort StudiesHIV InfectionsHumansMethadoneOpiate Substitution TreatmentOpioid-Related DisordersConceptsOpioid agonist therapyOpioid use disorderVeterans Aging Cohort StudyHIV statusUse disordersOpioid agonist treatmentAging Cohort StudyDiagnosis of HCVTwelve-month retentionPositive health outcomesOAT retentionAgonist therapyCohort studyHIV managementAgonist treatmentPredictors of retentionPatientsHealth outcomesHistory of homelessnessHIVLower likelihoodImproved likelihoodLikelihood of initiationBuprenorphineDisorders
2020
Trajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study.
Edelman EJ, Li Y, Barry D, Brennan Braden J, Crystal S, Kerns RD, Gaither JR, Gordon KS, Manhapra A, Merlin JS, Moore BA, Oldfield BJ, Park LS, Rentsch CT, Skanderson M, Williams EC, Justice AC, Tate JP, Becker WC, Marshall BDL. Trajectories of Self-Reported Opioid Use Among Patients With HIV Engaged in Care: Results From a National Cohort Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2020, 84: 26-36. PMID: 32267658, PMCID: PMC7147724, DOI: 10.1097/qai.0000000000002310.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCohort StudiesFemaleHIV InfectionsHumansMaleMiddle AgedOpioid-Related DisordersUnited StatesConceptsOpioid useOpioid use trajectoriesCohort studyPain interferenceSelf-reported opioid useVeterans Aging Cohort StudyVeterans Health Administration sitesInfrequent useOpioid use frequencyMarijuana useAging Cohort StudyNational cohort studyEvidence-based treatmentsGroup-based trajectory modelsProspective cohortBaseline factorsIllness severityMultivariable analysisBenzodiazepine medicationVA carePsychoactive medicationsPrescription painkillersPsychiatric symptomsHeroin useMultinomial logistic regression
2019
Predictors of timely opioid agonist treatment initiation among veterans with and without HIV
Wyse JJ, Robbins JL, McGinnis KA, Edelman EJ, Gordon AJ, Manhapra A, Fiellin DA, Moore BA, Korthuis PT, Gaither JR, Gordon K, Skanderson M, Barry DT, Crystal S, Justice A, Kraemer KL. Predictors of timely opioid agonist treatment initiation among veterans with and without HIV. Drug And Alcohol Dependence 2019, 198: 70-75. PMID: 30878769, PMCID: PMC6836871, DOI: 10.1016/j.drugalcdep.2019.01.038.Peer-Reviewed Original ResearchMeSH KeywordsAdultCohort StudiesFemaleHIVHIV InfectionsHumansMaleMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPrevalenceTime-to-TreatmentUnited StatesVeteransConceptsOpioid agonist therapyOpioid use disorderVeterans Aging Cohort StudyOAT initiationUninfected patientsClinical encountersNational observational cohortAging Cohort StudyAfrican American patientsImproved health outcomesAgonist therapyCohort studyObservational cohortTreatment initiationPredictive factorsEffective treatmentAdjusted modelUninfected controlsUse disordersPsychiatric diagnosisPWHClinical practicePatientsHealth outcomesRural residence
2017
Customized Recommendations and Reminder Text Messages for Automated, Computer-Based Treatment During Methadone
Moore BA, Buono FD, Printz DMB, Lloyd DP, Fiellin DA, Cutter CJ, Schottenfeld RS, Barry DT. Customized Recommendations and Reminder Text Messages for Automated, Computer-Based Treatment During Methadone. Experimental And Clinical Psychopharmacology 2017, 25: 485-495. PMID: 29251978, PMCID: PMC5737744, DOI: 10.1037/pha0000149.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPatient engagementReminder messagesPreliminary efficacy findingsMethadone-maintained patientsSubstance use disordersIllicit drug useRandomized trialsEfficacy findingsMethadone maintenanceUse disordersPatient useDrug useSystem functionBehavioral therapyComputer-based interventionsPatientsShort latencyTotal call timeTrial 2Trial 1Line callsSelf-management systemCall timeTotal contact timeEvaluation of an Integrated, Multidisciplinary Program to Address Unsafe Use of Opioids Prescribed for Pain
Becker WC, Edmond SN, Cervone DJ, Manhapra A, Sellinger JJ, Moore BA, Edens EL. Evaluation of an Integrated, Multidisciplinary Program to Address Unsafe Use of Opioids Prescribed for Pain. Pain Medicine 2017, 19: 1419-1424. PMID: 28371816, DOI: 10.1093/pm/pnx041.Peer-Reviewed Original ResearchConceptsPreliminary efficacyUnsafe useSubstance abuse/dependenceMultidisciplinary care teamSubstance use disorder diagnosisPrimary care physiciansAdvanced practice nursesUrine drug testingLength of treatmentStructured clinical assessmentNurse case managersAbuse/dependenceHealth system levelHigh-complexity patientsElectronic progress notesOpioid prescribedOpioid receiptCare physiciansPractice nursesPrimary careCare coordinationCare teamClinical assessmentCare modelClinic processes
2016
Interim Buprenorphine vs. Waiting List for Opioid Dependence
Sigmon SC, Ochalek TA, Meyer AC, Hruska B, Heil SH, Badger GJ, Rose G, Brooklyn JR, Schwartz RP, Moore BA, Higgins ST. Interim Buprenorphine vs. Waiting List for Opioid Dependence. New England Journal Of Medicine 2016, 375: 2504-2505. PMID: 28002704, PMCID: PMC5373028, DOI: 10.1056/nejmc1610047.Peer-Reviewed Original ResearchMeSH KeywordsBuprenorphineHumansNarcotic AntagonistsOpioid-Related DisordersPilot ProjectsWaiting ListsCognitive Behavioral Therapy Improves Treatment Outcomes for Prescription Opioid Users in Primary Care Buprenorphine Treatment
Moore BA, Fiellin DA, Cutter CJ, Buono FD, Barry DT, Fiellin LE, O'Connor PG, Schottenfeld RS. Cognitive Behavioral Therapy Improves Treatment Outcomes for Prescription Opioid Users in Primary Care Buprenorphine Treatment. Journal Of Substance Use And Addiction Treatment 2016, 71: 54-57. PMID: 27776678, PMCID: PMC5119533, DOI: 10.1016/j.jsat.2016.08.016.Peer-Reviewed Original ResearchConceptsOpioid-using patientsCognitive behavioral therapyUse patientsPhysician managementOpioid useTreatment outcomesBuprenorphine/naloxone treatmentHeroin use disorder patientsSelf-reported opioid useBehavioral therapyOpioid use groupPrevious drug treatmentUrine toxicology analysisEffects of CBTInjection drug useBaseline demographic differencesPrescription opioid usersBuprenorphine treatmentNaloxone treatmentOpioid abstinencePrescription opioidsOpioid usersOpioid categoryTreatment responseDrug treatment
2015
Bridging waitlist delays with interim buprenorphine treatment: Initial feasibility
Sigmon SC, Meyer A, Hruska B, Ochalek T, Rose G, Badger GJ, Brooklyn JR, Heil SH, Higgins ST, Moore BA, Schwartz RP. Bridging waitlist delays with interim buprenorphine treatment: Initial feasibility. Addictive Behaviors 2015, 51: 136-142. PMID: 26256469, PMCID: PMC4558243, DOI: 10.1016/j.addbeh.2015.07.030.Peer-Reviewed Original ResearchConceptsInterim buprenorphine treatmentBuprenorphine treatmentWeek 2ASI drug composite scoresIllicit opioid abstinenceOpioid-dependent adultsIllicit opioid useDrug composite scoresPercent of participantsInitial feasibilityPast-month drug useWaitlist delaysOpioid cravingOpioid withdrawalBuprenorphine administrationOpioid useSecondary outcomesBuprenorphine inductionDaily medicationOpioid abstinencePrimary outcomeIllicit opioidsOpioid dependenceWeek 12Agonist maintenance
2014
Primary Care–Based Buprenorphine Taper vs Maintenance Therapy for Prescription Opioid Dependence: A Randomized Clinical Trial
Fiellin DA, Schottenfeld RS, Cutter CJ, Moore BA, Barry DT, O’Connor P. Primary Care–Based Buprenorphine Taper vs Maintenance Therapy for Prescription Opioid Dependence: A Randomized Clinical Trial. JAMA Internal Medicine 2014, 174: 1947-1954. PMID: 25330017, PMCID: PMC6167926, DOI: 10.1001/jamainternmed.2014.5302.Peer-Reviewed Original ResearchConceptsPrescription opioid dependenceOngoing maintenance therapyIllicit opioid useMaintenance therapyOpioid dependenceBuprenorphine taperBuprenorphine therapyTaper groupMaintenance groupOpioid usePrimary careClinical trialsPrimary care-based treatmentSignificant public health burdenBuprenorphine maintenance therapyOngoing maintenance treatmentPrimary care physiciansEvidence-based guidelinesPrimary care sitesPublic health burdenWeeks of stabilizationHydrochloride therapyOpioid withdrawalBuprenorphine treatmentNaltrexone treatmentA pilot trial of a videogame-based exercise program for methadone maintained patients
Cutter CJ, Schottenfeld RS, Moore BA, Ball SA, Beitel M, Savant JD, Stults-Kolehmainen MA, Doucette C, Barry DT. A pilot trial of a videogame-based exercise program for methadone maintained patients. Journal Of Substance Use And Addiction Treatment 2014, 47: 299-305. PMID: 25012555, PMCID: PMC4487635, DOI: 10.1016/j.jsat.2014.05.007.Peer-Reviewed Original ResearchConceptsExercise interventionSubstance useSubstance use disorder treatmentMethadone-maintained patientsStudy completion ratesPhysical activity levelsGreater physical activityWii Fit PlusUse disorder treatmentExercise programSedentary controlsPilot trialPhysical activityDisorder treatmentActive game playPilot studyActivity levelsInterventionPatientsCompletion ratesHigh satisfactionFurther investigationTrialsPsychological wellnessParticipants
2013
HIV Testing and Sexual Risk Reduction Counseling in Office-Based Buprenorphine/Naloxone Treatment
Edelman EJ, Moore BA, Caffrey S, Sikkema KJ, Jones ES, Schottenfeld RS, Fiellin DA, Fiellin LE. HIV Testing and Sexual Risk Reduction Counseling in Office-Based Buprenorphine/Naloxone Treatment. Journal Of Addiction Medicine 2013, 7: 410-416. PMID: 24189173, DOI: 10.1097/adm.0b013e3182a3b603.Peer-Reviewed Original ResearchConceptsSexual risk reduction counselingRisk reduction counselingBuprenorphine/naloxone treatmentOpioid-dependent patientsReduction counselingSexual risk behaviorsHIV testingNaloxone treatmentHuman immunodeficiency virus (HIV) testingRisk behaviorsPreliminary efficacyVirus testingPatientsManual adherenceTreatment practicesProcess measuresCounseling sessionsSimilar proportionsHIVCounselingOutcomesTreatmentSessionsRandomizedTestingThe Recovery Line: A pilot trial of automated, telephone-based treatment for continued drug use in methadone maintenance
Moore BA, Fazzino T, Barry DT, Fiellin DA, Cutter CJ, Schottenfeld RS, Ball SA. The Recovery Line: A pilot trial of automated, telephone-based treatment for continued drug use in methadone maintenance. Journal Of Substance Use And Addiction Treatment 2013, 45: 63-69. PMID: 23375114, PMCID: PMC3642223, DOI: 10.1016/j.jsat.2012.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultAutomationCocaine-Related DisordersFeasibility StudiesFemaleHumansMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient Acceptance of Health CarePatient SatisfactionPilot ProjectsSubstance Abuse DetectionTelephoneTherapy, Computer-AssistedConceptsMethadone maintenanceLarge clinical trialsTelephone-based treatmentCurrent pilot studyPatient satisfactionClinical trialsPatient utilizationComputer-based treatmentPilot trialInitial efficacyInteractive voice response systemDrug usePatientsScreen outcomesVoice response systemPilot studyIllicit drugsTreatmentDaily useTrialsEfficacyOpioidsAbstinenceRecovery lineCocaineA Randomized Trial of Cognitive Behavioral Therapy in Primary Care-based Buprenorphine
Fiellin DA, Barry DT, Sullivan LE, Cutter CJ, Moore BA, O'Connor PG, Schottenfeld RS. A Randomized Trial of Cognitive Behavioral Therapy in Primary Care-based Buprenorphine. The American Journal Of Medicine 2013, 126: 74.e11-74.e17. PMID: 23260506, PMCID: PMC3621718, DOI: 10.1016/j.amjmed.2012.07.005.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPhysician managementBehavioral therapyOpioid useOpioid dependencePrimary careSelf-reported frequencyBuprenorphine/naloxone treatmentConsecutive weeksOpioid-dependent patientsIllicit opioid usePrimary care clinicsPrimary outcome measureWeeks of treatmentNaloxone treatmentOpioid abstinenceBuprenorphine/Care clinicsIllicit opioidsRandomized trialsUrine toxicologyClinical trialsStudy completionOutcome measuresCocaine use
2012
Counseling and Directly Observed Medication for Primary Care Buprenorphine Maintenance
Moore BA, Barry DT, Sullivan LE, O'Connor PG, Cutter CJ, Schottenfeld RS, Fiellin DA. Counseling and Directly Observed Medication for Primary Care Buprenorphine Maintenance. Journal Of Addiction Medicine 2012, 6: 205-211. PMID: 22614936, PMCID: PMC3419276, DOI: 10.1097/adm.0b013e3182596492.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPhysician managementObserved medicationBaseline characteristicsCBT sessionsOpioid-negative urinesIndividual CBT sessionsBuprenorphine maintenanceOpioid useMedication adherencePatient satisfactionPrimary careImproved outcomesTreatment outcomesSession attendanceNegative urineTreatment groupsGreater abstinenceCounseling intensityDrug useTherapist availabilityMedicationsBuprenorphinePatientsIndependent effectsBrief versus extended counseling along with buprenorphine/naloxone for HIV-infected opioid dependent patients
Tetrault JM, Moore BA, Barry DT, O'Connor PG, Schottenfeld R, Fiellin DA, Fiellin LE. Brief versus extended counseling along with buprenorphine/naloxone for HIV-infected opioid dependent patients. Journal Of Substance Use And Addiction Treatment 2012, 43: 433-439. PMID: 22938914, DOI: 10.1016/j.jsat.2012.07.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineBuprenorphine, Naloxone Drug CombinationCounselingDelivery of Health Care, IntegratedFeasibility StudiesFemaleFollow-Up StudiesHIV InfectionsHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsOpioid-Related DisordersPsychotherapy, BriefSubstance Abuse DetectionTime FactorsTreatment OutcomeViral LoadConceptsEnhanced medical managementPhysician managementDetectable HIV viral loadHIV treatment settingsOpioid-negative urinesBuprenorphine/naloxoneHIV viral loadOpioid-dependent patientsPercentage of subjectsUntreated opioid dependenceExtended counselingHIV clinicHIV outcomesBuprenorphine/Medical managementOpioid dependenceViral loadDependent patientsExtensive counselingClinical trialsContinuous abstinenceNegative urineTreatment settingsGroup differencesCounselingCost-Effectiveness of Long-Term Outpatient Buprenorphine-Naloxone Treatment for Opioid Dependence in Primary Care
Schackman BR, Leff JA, Polsky D, Moore BA, Fiellin DA. Cost-Effectiveness of Long-Term Outpatient Buprenorphine-Naloxone Treatment for Opioid Dependence in Primary Care. Journal Of General Internal Medicine 2012, 27: 669-676. PMID: 22215271, PMCID: PMC3358393, DOI: 10.1007/s11606-011-1962-8.Peer-Reviewed Original ResearchMeSH KeywordsBuprenorphineCost of IllnessCost-Benefit AnalysisDecision Support TechniquesDrug Administration ScheduleDrug CombinationsDrug CostsHealth Care CostsHumansLong-Term CareMedication AdherenceNaloxoneNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPrimary Health CareQuality-Adjusted Life YearsSensitivity and SpecificityUnited StatesConceptsQuality-adjusted life yearsBUP/NXProbabilistic sensitivity analysesBup/Stable patientsOpioid dependenceLife weightsStable opioid-dependent patientsIncremental cost-effectiveness ratioOpioid-dependent patientsOpioid-dependent individualsOffice-based settingSocietal cost savingsCost-effectiveness ratioDecision analytic modelBroader health systemBuprenorphine-naloxoneOpioid useCohort studyNaloxone treatmentCare physiciansAdditional researchPrimary carePatient costsHypothetical cohort
2010
Effect of Incarceration History on Outcomes of Primary Care Office-based Buprenorphine/Naloxone
Wang EA, Moore BA, Sullivan LE, Fiellin DA. Effect of Incarceration History on Outcomes of Primary Care Office-based Buprenorphine/Naloxone. Journal Of General Internal Medicine 2010, 25: 670-674. PMID: 20213205, PMCID: PMC2881960, DOI: 10.1007/s11606-010-1306-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineCriminalsFemaleHumansMaleMiddle AgedNaloxoneOffice VisitsOpioid-Related DisordersPrimary Health CareSocioeconomic FactorsTreatment OutcomeYoung AdultConceptsBuprenorphine/naloxoneHistory of incarcerationBuprenorphine/naloxone treatmentNaloxone treatmentBuprenorphine/Opioid dependenceTreatment outcomesCommunity health care providersOffice-based treatmentSimilar treatment outcomesPrimary care officesRandomized clinical trialsOpioid-dependent individualsHealth care providersMain resultsParticipantsClinical characteristicsCare officesClinical trialsCare providersSecondary analysisSimilar outcomesNaloxoneDependent individualsOutcomesIncarceration history
2007
Primary Care Office-based Buprenorphine Treatment: Comparison of Heroin and Prescription Opioid Dependent Patients
Moore BA, Fiellin DA, Barry DT, Sullivan LE, Chawarski MC, O’Connor P, Schottenfeld RS. Primary Care Office-based Buprenorphine Treatment: Comparison of Heroin and Prescription Opioid Dependent Patients. Journal Of General Internal Medicine 2007, 22: 527-530. PMID: 17372805, PMCID: PMC1829433, DOI: 10.1007/s11606-007-0129-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalgesics, OpioidBuprenorphineFemaleHeroinHeroin DependenceHumansMaleOffice VisitsOpioid-Related DisordersPrimary Health CareConceptsPrescription opioid useOpioid useOnly patientsPrescription opioidsTreatment outcomesBuprenorphine/naloxone maintenanceBuprenorphine/naloxone treatmentOpioid-negative urine samplesPrescription opioid-dependent patientsHepatitis C antibodyDrug treatment historyOpioid-dependent patientsPrimary care officesOffice-based settingClinical characteristicsBuprenorphine treatmentNaloxone treatmentBuprenorphine/Opioid dependenceCare officesDependent patientsTreatment responseC antibodyHeroin usePatients
2006
A Trial of Integrated Buprenorphine/Naloxone and HIV Clinical Care
Sullivan LE, Barry D, Moore BA, Chawarski MC, Tetrault JM, Pantalon MV, O'Connor PG, Schottenfeld RS, Fiellin DA. A Trial of Integrated Buprenorphine/Naloxone and HIV Clinical Care. Clinical Infectious Diseases 2006, 43: s184-s190. PMID: 17109305, DOI: 10.1086/508182.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, SublingualAdultAntiretroviral Therapy, Highly ActiveBuprenorphineDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesHIV InfectionsHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsOpioid-Related DisordersPilot ProjectsProbabilityReference ValuesRisk FactorsTreatment OutcomeConceptsHIV clinical careHIV-1 RNA copies/mLBuprenorphine/naloxone treatmentRNA copies/mLCopies/mLOpioid dependenceClinical careOpioid useNaloxone treatmentPhysician managementTreatment retentionHIV type 1 RNA levelsHIV-1 RNA levelsDose of buprenorphinePartial opioid agonistRNA levelsCD4 lymphocyte countBuprenorphine/naloxoneOpioid-dependent patientsUrine toxicology testsWeeks of treatmentHuman immunodeficiency virusUrine test resultsBetter treatment retentionUntreated opioid dependenceCounseling plus Buprenorphine–Naloxone Maintenance Therapy for Opioid Dependence
Fiellin DA, Pantalon MV, Chawarski MC, Moore BA, Sullivan LE, O'Connor PG, Schottenfeld RS. Counseling plus Buprenorphine–Naloxone Maintenance Therapy for Opioid Dependence. New England Journal Of Medicine 2006, 355: 365-374. PMID: 16870915, DOI: 10.1056/nejmoa055255.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineCocaine-Related DisordersCombined Modality TherapyCounselingFemaleHumansMaleNaloxoneNarcotic AntagonistsOpioid-Related DisordersConceptsStandard medical managementBuprenorphine-naloxone treatmentIllicit opioid useMedical managementOpioid dependenceWeekly medicationOpioid useIllicit opioidsWeekly counselingPrimary careUrine specimensConsecutive weeksProportion of patientsImproved treatment outcomesMaintenance therapyPrimary outcomeClinical trialsMedication distributionSimilar efficacyTreatment outcomesMedicationsSelf-reported frequencyPatientsFrequency of attendanceMean percentage