1991
Neurotensin modulates autoreceptor mediated dopamine effects on midbrain dopamine cell activity
Shi W, Bunney B. Neurotensin modulates autoreceptor mediated dopamine effects on midbrain dopamine cell activity. Brain Research 1991, 543: 315-321. PMID: 1676331, DOI: 10.1016/0006-8993(91)90043-u.Peer-Reviewed Original ResearchConceptsDA cellsCell activityFiring rateDA cell activityInteraction of neurotensinGlutamate-induced excitationEffects of neurotensinMidbrain dopamine cell activityDopamine cell activityMidbrain dopamine neuronsSpecific D2 agonistMicroiontophoretic techniquesD2 agonistDopamine neuronsD2 receptorsDopamine effectsSpontaneous activityNeurotensinNT effectsLocal ejectionInhibitionSignificant changesCellsCell levelSame cells
1985
Opposing effects of striatonigral feedback pathways on midbrain dopamine cell activity
Grace A, Bunney B. Opposing effects of striatonigral feedback pathways on midbrain dopamine cell activity. Brain Research 1985, 333: 271-284. PMID: 2986775, DOI: 10.1016/0006-8993(85)91581-1.Peer-Reviewed Original ResearchConceptsInhibitory postsynaptic potentialsDA cellsStriatal stimulationReticulata neuronsDA neuronsRebound depolarizationReversal potentialSubstantia nigra zona reticulata neuronsStriatonigral GABAergic pathwayMidbrain dopamine cell activityDopamine cell activitySame stimulation parametersChloride injectionChloride channel blockerChloride reversal potentialSimilar reversal potentialsSimilar time courseGABAergic pathwayGABAergic projectionsZona reticulataPostsynaptic potentialsSystemic injectionChannel blockersIntracellular recordingsStriatal cells
1984
Antipsychotic drug effects on the electrical activity of dopaminergic neurons
Bunney B. Antipsychotic drug effects on the electrical activity of dopaminergic neurons. Trends In Neurosciences 1984, 7: 212-215. DOI: 10.1016/s0166-2236(84)80013-2.Peer-Reviewed Original ResearchClinical effectsAntipsychotic drugsChronic studiesAntipsychotic drug effectsDopamine cell activityCell firing rateMechanism of actionDopaminergic neuronsDrug effectsCell activityElectrophysiological techniquesFiring rateBehavioral effectsDrugsElectrical activityTime-dependent changesNeuronsCellular sitesChemical messengersSpecific actionsActivity
1978
Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity
Bunney B, Grace A. Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity. Life Sciences 1978, 23: 1715-1727. PMID: 31529, DOI: 10.1016/0024-3205(78)90471-x.Peer-Reviewed Original ResearchConceptsChronic haloperidol treatmentDA cellsHaloperidol treatmentControl animalsCell activityExtracellular single-unit recordingsDopaminergic cell activityDopaminergic neuronal activityNigral DA cellsNeurological side effectsDopamine cell activitySingle-unit recordingsFeedback pathwaysComparison of effectsDA neuronsTime-dependent mannerMicroiontophoretic techniquesClinical effectsKainic acidAntipsychotic drugsDepolarization blockCaudate nucleusNeuronal activitySide effectsUnit recordings