1990
Neurotensin attenuates dopamine D2 agonist quinpirole-induced inhibition of midbrain dopamine neurons
Shi W, Bunney B. Neurotensin attenuates dopamine D2 agonist quinpirole-induced inhibition of midbrain dopamine neurons. Neuropharmacology 1990, 29: 1095-1097. PMID: 1982340, DOI: 10.1016/0028-3908(90)90119-c.Peer-Reviewed Original ResearchConceptsD2 agonistDA cellsSingle-unit recording techniquesMidbrain DA neuronsCentral DA systemsDopamine D2 agonistMidbrain dopamine neuronsSpecific D2 agonistDA neuronsIntracerebroventricular administrationDopamine neuronsSpontaneous activityDA systemInhibitory effectRecording techniquesAgonistsNeuronsBiochemical studiesCellsQuinpiroleNeurotensinRatsAdministration
1988
The effects of pertussis toxin on autoreceptor-mediated inhibition of dopamine synthesis in the rat striatum.
Bean A, Shepard P, Bunney B, Nestler E, Roth R. The effects of pertussis toxin on autoreceptor-mediated inhibition of dopamine synthesis in the rat striatum. Molecular Pharmacology 1988, 34: 715-8. PMID: 2974120.Peer-Reviewed Original ResearchConceptsPertussis toxin injectionDopamine synthesisToxin injectionDopamine autoreceptorsRat striatumPertussis toxinAutoreceptor-mediated inhibitionDopamine agonist apomorphineG proteinsAgonist apomorphineUnilateral administrationControl ratsSystemic administrationStriatal tissueEffects of activationAutoreceptorsApomorphineStriatumRatsAdministrationInjectionToxinActivationStriataAgonistsEffects of apamin on the discharge properties of putative dopamine-containing neurons in vitro
Shepard P, Bunney B. Effects of apamin on the discharge properties of putative dopamine-containing neurons in vitro. Brain Research 1988, 463: 380-384. PMID: 3196925, DOI: 10.1016/0006-8993(88)90414-3.Peer-Reviewed Original ResearchConceptsDopamine-containing neuronsPutative dopamine-containing neuronsEffects of apaminCalcium-activated potassium conductanceCalcium-activated potassium channelsBrain slice preparationApamin administrationSubstantia nigraSlice preparationNeuronal excitabilityBursting activityPotassium conductancePotassium channelsNeuronsSelective inhibitorApaminRegular activitiesExcitabilityAdministrationNigraEffects of Acute and Chronic Neuroleptic Treatment on the Activity of Mid brain Dopamine Neuronsa
BUNNEY B. Effects of Acute and Chronic Neuroleptic Treatment on the Activity of Mid brain Dopamine Neuronsa. Annals Of The New York Academy Of Sciences 1988, 537: 77-85. PMID: 2904786, DOI: 10.1111/j.1749-6632.1988.tb42097.x.Peer-Reviewed Original ResearchConceptsAD administrationDA releaseDA cell activityChronic neuroleptic treatmentMidbrain DA neuronsRelease of DAEffects of AcuteNeurological side effectsDA neuronsNeuroleptic treatmentAcute effectsNerve terminalsSpontaneous activitySide effectsCell activityMarked increaseAdministrationProjection areaPrimary effectReleaseAcuteMarked effectNeuronsActivityBiochemical techniquesIntracellular studies of dopamine neurons in vitro: pacemakers modulated by dopamine
Silva N, Bunney B. Intracellular studies of dopamine neurons in vitro: pacemakers modulated by dopamine. European Journal Of Pharmacology 1988, 149: 307-315. PMID: 3409955, DOI: 10.1016/0014-2999(88)90661-9.Peer-Reviewed Original ResearchConceptsSensitive neuronsInput resistanceAdministration of DADA-sensitive neuronsSelective D2 antagonistPacemaker-like activityHigh input resistanceZona compactaDA actionD2 antagonistDopamine neuronsIntracellular recordingsFiring rateIntracellular studyNeuronsReversal potentialTissue slicesDopamineHyperpolarizationSulpirideAntagonistCompactaAdministration
1986
Midbrain Dopamine Neurons: Electrophysiological Studies on the Acute Effects of Estrogen
Chiodo L, Glazer W, Bunney B. Midbrain Dopamine Neurons: Electrophysiological Studies on the Acute Effects of Estrogen. Satellite Symposia Of The Ninth IUPHAR Congress 1986, 303-311. DOI: 10.1007/978-1-349-07431-0_21.Peer-Reviewed Original Research
1982
A modification of the rapid glyoxylic acid technique permits visualization of serotonergic and hypothalamic dopaminergic neurons
Rassmussen S, Bunney B. A modification of the rapid glyoxylic acid technique permits visualization of serotonergic and hypothalamic dopaminergic neurons. Journal Of Neuroscience Methods 1982, 6: 139-144. PMID: 6750255, DOI: 10.1016/0165-0270(82)90024-3.Peer-Reviewed Original ResearchConceptsGlyoxylic acid techniqueHypothalamic dopaminergic neuronsTryptophan hydroxylase inhibitorHypothalamic cell groupsTryptophan pretreatmentCatecholaminergic neuronsDopaminergic neuronsHypothalamic neuronsPara-chlorophenylalanineDendritic fieldsSerotonergic systemCatecholamine systemsColchicine administrationHydroxylase inhibitorColchicine pretreatmentCell groupsNeuronsAcid techniqueMethod of choiceReliable visualizationPretreatmentDopaminergicHistofluorescenceImmunocytohistochemistryAdministration
1973
ELECTROPHYSIOLOGICAL EFFECTS OF AMPHETAMINE ON DOPAMINERGIC NEURONS
BUNNEY B, AGHAJANIAN G. ELECTROPHYSIOLOGICAL EFFECTS OF AMPHETAMINE ON DOPAMINERGIC NEURONS. 1973, 957-962. DOI: 10.1016/b978-0-08-017922-3.50182-9.Peer-Reviewed Original ResearchDA synthesisDopaminergic neuronsDA cellsElectrophysiological effectsD-AMPLow ejection currentsTyrosine hydroxylase inhibitorIntra-peritoneal administrationCell firing rateDA neuronsDA receptorsDepressant effectOlfactory tubercleEjection currentsIntravenous administrationCaudate nucleusHydroxylase inhibitorPostsynaptic cellFiring rateMinimal responseNeuronsBlockadeAntipsychotic phenothiazinesAdministrationAmphetamine