2019
Individuals with psychosis and a lifetime history of cannabis use show greater deficits in emotional experience compared to non-using peers
Martin A, Lysaker PH. Individuals with psychosis and a lifetime history of cannabis use show greater deficits in emotional experience compared to non-using peers. Journal Of Mental Health 2019, 29: 77-83. PMID: 30822177, DOI: 10.1080/09638237.2018.1487540.Peer-Reviewed Original ResearchMeSH KeywordsAdultEmotionsFemaleHumansMaleMarijuana SmokingMiddle AgedPeer GroupPsychotic DisordersSchizophrenic PsychologySelf ReportConceptsEmotional Expressivity ScaleEmotional experienceSocial Functioning ScaleEmotional expressionAnticipatory pleasureLifetime cannabisSocial functioningGreater deficitsSocial functionCannabis useNon-using peersAnticipation of pleasureExperience of pleasurePoor social functionEmotional expressivityLifetime historyAnticipatory anhedoniaProsocial activitiesActive cannabisPleasure ScaleTemporal experienceHistory of cannabisFunctioning ScaleEarly psychosisPrevious research
2018
The effects of cannabidiol (CBD) on cognition and symptoms in outpatients with chronic schizophrenia a randomized placebo controlled trial
Boggs DL, Surti T, Gupta A, Gupta S, Niciu M, Pittman B, Schnakenberg Martin AM, Thurnauer H, Davies A, D’Souza D, Ranganathan M. The effects of cannabidiol (CBD) on cognition and symptoms in outpatients with chronic schizophrenia a randomized placebo controlled trial. Psychopharmacology 2018, 235: 1923-1932. PMID: 29619533, DOI: 10.1007/s00213-018-4885-9.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdultAffectAntipsychotic AgentsCannabidiolChronic DiseaseCognitionCognitive DysfunctionDouble-Blind MethodFemaleFollow-Up StudiesHumansMaleMental Status and Dementia TestsMiddle AgedOutpatientsPsychiatric Status Rating ScalesSchizophreniaSchizophrenic PsychologyTreatment OutcomeConceptsMATRICS Consensus Cognitive BatterySide effectsChronic schizophreniaAntipsychotic-treated patientsMovement side effectsFixed-dose studyPlacebo-treated subjectsWeeks of treatmentPANSS total scoreEffects of cannabidiolWorsening of moodNegative Syndrome ScaleAntipsychotic-treated outpatients× time effect× time interactionMCCB composite scoreOral cannabidiolCBD groupClinical trialsParallel groupPANSS scoresMethodsThis studyPsychotic symptomsConsensus Cognitive BatterySyndrome Scale
2017
The positive link between executive function and lifetime cannabis use in schizophrenia is not explained by current levels of superior social cognition
Helle S, Løberg EM, Gjestad R, Martin A, Lysaker PH. The positive link between executive function and lifetime cannabis use in schizophrenia is not explained by current levels of superior social cognition. Psychiatry Research 2017, 250: 92-98. PMID: 28152399, DOI: 10.1016/j.psychres.2017.01.047.Peer-Reviewed Original ResearchConceptsSocial cognitionTheory of mindExecutive functionCannabis useBell-Lysaker Emotion Recognition TestEmotion Recognition TestExecutive Functioning ScaleBetter executive functionRegular cannabis useStructural equation modelingHinting testIllicit substancesNeurocognitive vulnerabilityRecognition testNeurocognitive performanceNeurocognitive deficitsCognitionEquation modelingFlexibility componentsAlcohol useFunctioning ScaleLifetime cannabisIndirect effectsPositive linkSchizophrenia