1987
The cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteins
Parks T, Nairn A, Greengard P, Jamieson J. The cyclic nucleotide-dependent phosphorylation of aortic smooth muscle membrane proteins. Archives Of Biochemistry And Biophysics 1987, 255: 361-371. PMID: 3036005, DOI: 10.1016/0003-9861(87)90404-8.Peer-Reviewed Original ResearchConceptsG-kinaseA-kinaseGs proteinMembrane proteinsCyclic nucleotide-dependent phosphorylationCAMP-dependent protein kinase activityCGMP-dependent protein kinaseKinase catalytic subunitEndogenous A-kinaseProtein kinase activityPeptide mappingTwo-dimensional peptide mappingMembrane-bound formCyclic nucleotidesHigh-salt washMuscle membrane proteinsCatalytic subunitFunctional homologyProtein kinasePhosphorylation stateCytosolic formKinase activitySalt washIntracellular concentrationSoluble form
1986
Protein phosphorylation in cultured endothelial cells
Mackie K, Lai Y, Nairn A, Greengard P, Pitt B, Lazo J. Protein phosphorylation in cultured endothelial cells. Journal Of Cellular Physiology 1986, 128: 367-374. PMID: 3745280, DOI: 10.1002/jcp.1041280304.Peer-Reviewed Original ResearchConceptsCalcium/calmodulin-dependent protein kinaseCalmodulin-dependent protein kinaseCyclic AMP-dependent protein kinaseAMP-dependent protein kinaseProtein kinase activityProtein kinaseKinase activityCyclic GMP-dependent protein kinase activityRespective substrate proteinsProtein phosphorylation systemsProtein kinase CSubstrate proteinsProtein phosphorylationPhosphorylation systemEndothelial cellsNumerous substratesTyrosine kinaseKinase CPulmonary artery endothelial cellsKinaseCultured endothelial cellsArtery endothelial cellsSimilar culture conditionsCulture conditionsCells