1999
Effect of catecholamine depletion on lithium-induced long-term remission of bipolar disorder
Anand A, Darnell A, Miller H, Berman R, Cappiello A, Oren D, Woods S, Charney D. Effect of catecholamine depletion on lithium-induced long-term remission of bipolar disorder. Biological Psychiatry 1999, 45: 972-978. PMID: 10386179, DOI: 10.1016/s0006-3223(98)00293-5.Peer-Reviewed Original ResearchConceptsLong-term remissionBipolar disorderCatecholamine depletionLithium therapyHypomanic symptomsLong-term lithium therapyRandomized double-blind mannerDSM-IV bipolar disorderDouble-blind mannerMechanism of preventionTransient relapseManic relapsePlacebo administrationSerum levelsCatecholamine systemsHomovanillic acidRemissionRelapseDisordersTherapyTest sessionsSymptomsSubjectsSignificant changesMood indices
1997
Effects of Acute Tryptophan Depletion in Lithium-Remitted Manic Patients: A Pilot Study
Cappiello A, Sernyak M, Malison R, McDougle C, Heninger G, Price L. Effects of Acute Tryptophan Depletion in Lithium-Remitted Manic Patients: A Pilot Study. Biological Psychiatry 1997, 42: 1076-1078. PMID: 9386862, DOI: 10.1016/s0006-3223(97)00329-6.Peer-Reviewed Original Research