Antidepressants and suicide risk: how did specific information in FDA safety warnings affect treatment patterns?
Busch SH, Frank RG, Leslie DL, Martin A, Rosenheck RA, Martin EG, Barry CL. Antidepressants and suicide risk: how did specific information in FDA safety warnings affect treatment patterns? Psychiatric Services 2010, 61: 11-6. PMID: 20044412, PMCID: PMC2801076, DOI: 10.1176/appi.ps.61.1.11.Peer-Reviewed Original ResearchConceptsMajor depressive disorderAntidepressant useTreatment patternsDepressive disorderFDA safety warningsSpecific safety informationThomson Reuters MarketScanUse of paroxetineRisk of suicidalitySafety warningsAntidepressant treatmentOutpatient visitsTreatment episodesTreatment recommendationsPractice patternsNew episodesDrug AdministrationSuicide riskFDA recommendationsDepressed childrenU.S. FoodFDAAntidepressantsChildrenEvidence of increases