2021
Learning About and Destigmatizing Substance Use Disorders: a Video-Based Educational Module Using Simulated Patients
Fuehrlein B, Hochschild A, Goldman M, Amsalem D, Chilton J, Martin A. Learning About and Destigmatizing Substance Use Disorders: a Video-Based Educational Module Using Simulated Patients. Academic Psychiatry 2021, 46: 342-346. PMID: 34751939, PMCID: PMC8577171, DOI: 10.1007/s40596-021-01559-z.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersTreatment of patientsPrimary outcomeMedical disordersSame clinicianClinical scenariosPatientsEducational moduleMethodsThe authorsSynchronous videoconferencingDisordersSimulated patientsObjectiveThe authorsSecond-year medical studentsAlcoholics AnonymousScoresMedical studentsSUDMeasurable changesCliniciansBaseline
2020
The Mental Status Exam: An Online Teaching Exercise Using Video-Based Depictions by Simulated Patients
Martin A, Jacobs A, Krause R, Amsalem D. The Mental Status Exam: An Online Teaching Exercise Using Video-Based Depictions by Simulated Patients. MedEdPORTAL 2020, 16: 10947. PMID: 32875093, PMCID: PMC7450674, DOI: 10.15766/mep_2374-8265.10947.Peer-Reviewed Original ResearchConceptsMental status examUndergraduate medical educationObsessive-compulsive disorderPhysical examClinical dataPsychiatric signsBipolar disorderScoring toolPatientsEntrustable professional activitiesSimulated patientsClinical psychiatryVideo clipsExerciseDisordersIncremental numberExamMedical educationExperienced learnersOnline exercisesTeaching exerciseProfessional activityVolunteer studentsEducational complementShort video clips
2016
College students with autism spectrum disorders: A growing role for adult psychiatrists
van Schalkwyk GI, Beyer C, Martin A, Volkmar FR. College students with autism spectrum disorders: A growing role for adult psychiatrists. Journal Of American College Health 2016, 64: 575-579. PMID: 27347704, DOI: 10.1080/07448481.2016.1205072.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderAttention-deficit/hyperactivity disorderSpectrum disorderCollege mental health practitionersMental health practitionersExecutive functionMental health needsInattentive symptomsHyperactivity disorderPsychiatric difficultiesCollege studentsClinical presentationPatient's clinical presentationMore side effectsFemale studentsLimited evidence baseApproach treatmentHealth practitionersStudentsDisordersEvidence baseCase reportHealth needsDiagnostic considerationsSide effects
2009
Relation Between Amygdala Structure and Function in Adolescents With Bipolar Disorder
Kalmar JH, Wang F, Chepenik LG, Womer FY, Jones MM, Pittman B, Shah MP, Martin A, Constable RT, Blumberg HP. Relation Between Amygdala Structure and Function in Adolescents With Bipolar Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2009, 48: 636-642. PMID: 19454919, PMCID: PMC2867040, DOI: 10.1097/chi.0b013e31819f6fbc.Peer-Reviewed Original ResearchConceptsAmygdala volumeBipolar disorderInverse associationAmygdala structureMagnetic resonance imaging (MRI) scansAmygdala responseFunctional magnetic resonance imaging (fMRI) scansResonance imaging scansPossible pathophysiological linkSignificant inverse associationSmaller amygdala volumesFunctional magnetic resonancePathophysiological linkImaging scansBD groupHighest amygdala responseEmotional stimuliBD participantsElevated responseNeuroimaging sessionAdolescentsAmygdalaPrevious reportsPreliminary findingsDisorders
2007
Health Care Expenditures Associated With Autism Spectrum Disorders
Leslie DL, Martin A. Health Care Expenditures Associated With Autism Spectrum Disorders. JAMA Pediatrics 2007, 161: 350-355. PMID: 17404131, DOI: 10.1001/archpedi.161.4.350.Peer-Reviewed Original ResearchConceptsHealth care expendituresCare expendituresMental disordersAdolescents 17 yearsAutism spectrum disorderMedical care settingsAverage health care expendituresPrescription drug expendituresHealth care systemAnnual inpatientRetrospective analysisCare settingsSpectrum disorderPrevalence ratesProactive treatmentASD prevalence ratesEarly identificationPatientsDrug expendituresCare systemVulnerable populationsDisordersHealth insuranceTotal expenditureHealth insurers
2005
Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder
Blumberg HP, Fredericks C, Wang F, Kalmar JH, Spencer L, Papademetris X, Pittman B, Martin A, Peterson BS, Fulbright RK, Krystal JH. Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder. Bipolar Disorders 2005, 7: 570-576. PMID: 16403182, PMCID: PMC2291299, DOI: 10.1111/j.1399-5618.2005.00264.x.Peer-Reviewed Original ResearchConceptsAmygdala volumeBipolar disorderYoung adultsAmygdala volume abnormalitiesTotal brain volumeHigh-resolution magnetic resonancePreliminary evidenceSubjects longitudinal designPersistent abnormalitiesMixed-model statistical analysisBD IVolume abnormalitiesHealthy comparison participantsBrain volumeHealthy participantsAbnormalitiesAdultsAdolescentsComparison participantsAmygdalaDevelopmental epochsDisordersLongitudinal designParticipantsMagnetic resonanceChanges in child and adolescent inpatient psychiatric admission diagnoses between 1995 and 2000
Harpaz-Rotem I, Leslie DL, Martin A, Rosenheck RA. Changes in child and adolescent inpatient psychiatric admission diagnoses between 1995 and 2000. Social Psychiatry And Psychiatric Epidemiology 2005, 40: 642-647. PMID: 16133747, DOI: 10.1007/s00127-005-0923-0.Peer-Reviewed Original ResearchConceptsSpecific mental health disordersPrivate health insurance claimsPsychiatric inpatient settingsMental health disordersPsychiatric inpatient servicesSubstance abuse disordersHealth insurance claimsMental health problemsAdmission diagnosisHospitalized childrenNationwide databaseInpatient settingOdds ratioAbuse disordersPsychiatric diagnosisInpatient servicesHealth disordersBipolar disorderHealth problemsPrevalenceSignificant decreaseDisordersChildrenDiagnosisInsurance claims
2004
Is the Party Over? Cannabis and Juvenile Psychiatric Disorder: The Past 10 Years
REY JM, MARTIN A, KRABMAN P. Is the Party Over? Cannabis and Juvenile Psychiatric Disorder: The Past 10 Years. Journal Of The American Academy Of Child & Adolescent Psychiatry 2004, 43: 1194-1205. PMID: 15381886, DOI: 10.1097/01.chi.0000135623.12843.60.Peer-Reviewed Original ResearchConceptsJuvenile psychiatric disordersPsychiatric disordersOnset of schizophreniaRole of cannabisMental health effectsRate of useRegular marijuana usePsychotic illnessDepressive symptomsRegular cannabisMental disordersSuicidal behaviorPsychosocial functioningLiterature databasesSystematic searchHealth effectsLate increaseCannabisDisordersAdolescent dataBehavioral problemsRecent dataMarijuana useCannabis researchEvidence pointsSignificance of Adolescent Neurodevelopment for the Neural Circuitry of Bipolar Disorder
BLUMBERG HP, KAUFMAN J, MARTIN A, CHARNEY DS, KRYSTAL JH, PETERSON BS. Significance of Adolescent Neurodevelopment for the Neural Circuitry of Bipolar Disorder. Annals Of The New York Academy Of Sciences 2004, 1021: 376-383. PMID: 15251913, DOI: 10.1196/annals.1308.048.Peer-Reviewed Original ResearchConceptsNeural systemsCourse of adolescenceMajor developmental changesExecutive controlAdolescent neurodevelopmentEarly adolescenceLate adolescenceDevelopmental epochsNeural circuitryNeurodevelopmental modelDevelopmental changesEarly adulthoodAdolescenceSubcortical componentsBipolar disorderDeficitsImportant implicationsEmotionsVPFCDisordersAmygdalaEarly signsAdulthoodTreatment strategiesParticular components
2003
Low-Dose Fluvoxamine Treatment of Children and Adolescents with Pervasive Developmental Disorders: A Prospective, Open-Label Study
Martin A, Koenig K, Anderson GM, Scahill L. Low-Dose Fluvoxamine Treatment of Children and Adolescents with Pervasive Developmental Disorders: A Prospective, Open-Label Study. Journal Of Autism And Developmental Disorders 2003, 33: 77-85. PMID: 12708582, DOI: 10.1023/a:1022234605695.Peer-Reviewed Original ResearchConceptsPervasive developmental disorderSelective serotonin reuptake inhibitor responseOpen-label studyOpen-label trialLow-dose fluvoxamineDevelopmental disordersPremature discontinuationClinical responseFluvoxamine treatmentPartial respondersMean ageSerotonin levelsSelect childrenPubertal statusInhibitor responseBehavioral activationFluvoxamineChildrenFurther investigationDisordersTreatmentGender differencesAdolescentsSubjectsTolerability
2001
Methodological Issues in Designing a Multisite Trial of Risperidone in Children and Adolescents with Autism
Scahill L, McCracken J, McDougle C, Aman M, Arnold L, Tierney E, Cronin P, Davies M, Ghuman J, Gonzalez N, Koenig K, Lindsay R, Martin A, McGough J, Posey D, Swiezy N, Volkmar F, Ritz L, Vitiello B. Methodological Issues in Designing a Multisite Trial of Risperidone in Children and Adolescents with Autism. Journal Of Child And Adolescent Psychopharmacology 2001, 11: 377-388. PMID: 11838820, DOI: 10.1089/104454601317261555.Peer-Reviewed Original ResearchConceptsPlacebo-controlled studyPlacebo-controlled discontinuation studyAutistic disorderSafety of risperidoneStudy of RisperidoneStandard pharmacological treatmentSelf-injurious behaviorDiscontinuation studyPharmacological treatmentClinical trialsInclusion criteriaLong-term effectsSevere tantrumsTrial designClinical relevanceClinical practiceLength of trialRisperidoneMultisite trialStudy designContinuous treatmentTrialsTreatment effectsDisordersMaintenance phase
2000
Assessment in Multisite Randomized Clinical Trials of Patients with Autistic Disorder: The Autism RUPP Network
Arnold L, Aman M, Martin A, Collier-Crespin A, Vitiello B, Tierney E, Asarnow R, Bell-Bradshaw F, Freeman B, Gates-Ulanet P, Klin A, McCracken J, McDougle C, McGough J, Posey D, Scahill L, Swiezy N, Ritz L, Vokmar F. Assessment in Multisite Randomized Clinical Trials of Patients with Autistic Disorder: The Autism RUPP Network. Journal Of Autism And Developmental Disorders 2000, 30: 99-111. PMID: 10832774, DOI: 10.1023/a:1005451304303.Peer-Reviewed Original ResearchConceptsAutism Diagnostic InterviewChildren/adolescentsAutistic disorders symptomsNeuropsychological testsDisorder symptomsLower functioningAutistic disorderCore featuresTest developersDiagnostic InterviewProblem presentationPediatric psychopharmacologyAutismIndividual changesTreatment respondersTarget symptomsSecondary symptomsCommunication problemsMethodological challengesAssessment strategiesSubject heterogeneityIQPharmacological treatmentDisordersClinical Global Impression
1999
Higher-Functioning Pervasive Developmental Disorders: Rates and Patterns of Psychotropic Drug Use
MARTIN A, SCAHILL L, KLIN A, VOLKMAR F. Higher-Functioning Pervasive Developmental Disorders: Rates and Patterns of Psychotropic Drug Use. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 923-931. PMID: 10405512, DOI: 10.1097/00004583-199907000-00024.Peer-Reviewed Original ResearchConceptsPsychotropic drug useHigher-functioning pervasive developmental disordersPervasive developmental disorderTarget symptomsDrug useMedication use patternsPsychotropic medication useDevelopmental disordersMedication history informationMore medicationsMedication useClinical presentationPsychiatric comorbidityClinical variablesPsychotropic agentsDrug classesClinical heterogeneityDisordersSymptomsSubjectsAsperger's disorderFull Scale IQComorbiditiesMedicationsAntidepressants