2011
The Risk of Incident Coronary Heart Disease Among Veterans With and Without HIV and Hepatitis C
Freiberg MS, Chang CC, Skanderson M, McGinnis K, Kuller LH, Kraemer KL, Rimland D, Goetz MB, Butt AA, Barradas M, Gibert C, Leaf D, Brown ST, Samet J, Kazis L, Bryant K, Justice AC. The Risk of Incident Coronary Heart Disease Among Veterans With and Without HIV and Hepatitis C. Circulation Cardiovascular Quality And Outcomes 2011, 4: 425-432. PMID: 21712519, PMCID: PMC3159506, DOI: 10.1161/circoutcomes.110.957415.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHepatitis C virusHIV-HCVCensoring eventVeterans Aging Cohort Study Virtual CohortIncident coronary heart diseaseCoronary heart disease riskHeart disease riskCoronary heart diseaseHIV-1 RNARisk of CHDIncidence of CHDHCV statusVeteran EnrolleesAdjusted riskAntiretroviral therapyCD4 countCHD eventsHCV infectionHepatitis CCHD riskImmunodeficiency virusC virusHeart diseaseRisk factorsRisk of Heart Failure With Human Immunodeficiency Virus in the Absence of Prior Diagnosis of Coronary Heart Disease
Butt AA, Chang CC, Kuller L, Goetz MB, Leaf D, Rimland D, Gibert CL, Oursler KK, Rodriguez-Barradas MC, Lim J, Kazis LE, Gottlieb S, Justice AC, Freiberg MS. Risk of Heart Failure With Human Immunodeficiency Virus in the Absence of Prior Diagnosis of Coronary Heart Disease. JAMA Internal Medicine 2011, 171: 737-743. PMID: 21518940, PMCID: PMC3687533, DOI: 10.1001/archinternmed.2011.151.Peer-Reviewed Original ResearchConceptsIncident HF eventsHeart failureCoronary heart diseaseCopies/mLRisk factorsHIV infectionHF eventsHeart diseaseHigh riskVeterans Aging Cohort Study Virtual CohortHIV-1 RNA levelsRisk of HFCoronary heart disease eventsHuman immunodeficiency virus (HIV) infectionRNA levelsIncident heart failureOngoing viral replicationRetrospective cohort studyHeart disease eventsImmunodeficiency virus infectionHuman immunodeficiency virusVACS-VCVeteran EnrolleesCohort studyPrior diagnosis
2009
Hepatitis C Virus Infection and the Risk of Coronary Disease
Butt AA, Xiaoqiang W, Budoff M, Leaf D, Kuller LH, Justice AC. Hepatitis C Virus Infection and the Risk of Coronary Disease. Clinical Infectious Diseases 2009, 49: 225-232. PMID: 19508169, PMCID: PMC3077953, DOI: 10.1086/599371.Peer-Reviewed Original ResearchMeSH KeywordsAdultCoronary DiseaseFemaleHepatitis CHumansMaleMiddle AgedRisk AssessmentRisk FactorsVeteransConceptsCoronary artery diseaseHepatitis C virus infectionC virus infectionTraditional risk factorsHigh riskHCV infectionControl subjectsRisk factorsVirus infectionRisk of CADMean total plasma cholesterolLow-density lipoprotein cholesterolCox proportional hazards modelHCV Infected VeteransTotal plasma cholesterolFavorable risk profileProportional hazards modelVeterans Affairs facilitiesLower lipid levelsLipoprotein cholesterolObservational cohortRenal failureArtery diseaseCoronary diseaseMultivariable analysisThe Association Between the Receipt of Lipid Lowering Therapy and HIV Status Among Veterans Who Met NCEP/ATP III Criteria for the Receipt of Lipid Lowering Medication
Freiberg MS, Leaf DA, Goulet JL, Goetz MB, Oursler KK, Gibert CL, Rodriguez-Barradas MC, Butt AA, Justice AC. The Association Between the Receipt of Lipid Lowering Therapy and HIV Status Among Veterans Who Met NCEP/ATP III Criteria for the Receipt of Lipid Lowering Medication. Journal Of General Internal Medicine 2009, 24: 334-340. PMID: 19127386, PMCID: PMC2642578, DOI: 10.1007/s11606-008-0891-7.Peer-Reviewed Original ResearchConceptsNCEP/ATP III criteriaATP III criteriaHIV viral loadViral loadAdult Treatment Panel guidelinesHigher HIV viral loadFive-site studyLipid lowering medicationsVeterans Aging CohortHIV infection statusLipid-Lowering TherapyProspective observational cohortCross-sectional analysisHIV-HCVLowering therapiesModifiable mediatorsObservational cohortResultsThe prevalenceHIV infectionHIV statusPharmacy dataCardiovascular diseasePanel guidelinesMAIN OUTCOMELow prevalence