HIV Status, Burden of Comorbid Disease, and Biomarkers of Inflammation, Altered Coagulation, and Monocyte Activation
Armah KA, McGinnis K, Baker J, Gibert C, Butt AA, Bryant KJ, Goetz M, Tracy R, Oursler KK, Rimland D, Crothers K, Rodriguez-Barradas M, Crystal S, Gordon A, Kraemer K, Brown S, Gerschenson M, Leaf DA, Deeks SG, Rinaldo C, Kuller LH, Justice A, Freiberg M. HIV Status, Burden of Comorbid Disease, and Biomarkers of Inflammation, Altered Coagulation, and Monocyte Activation. Clinical Infectious Diseases 2012, 55: 126-136. PMID: 22534147, PMCID: PMC3493182, DOI: 10.1093/cid/cis406.Peer-Reviewed Original ResearchConceptsBiomarkers of inflammationVeterans Aging Cohort StudyAltered coagulationMonocyte activationUninfected veteransCardiovascular diseaseElevated biomarkersComorbid conditionsHigh prevalenceCD4 cell countElevated IL-6Aging Cohort StudyOngoing HIV replicationPrevalent cardiovascular diseaseHIV-1 RNAHuman immunodeficiency virusCopies/mLElevated sCD14More dyslipidemiaCD4 countHepatitis CCohort studyComorbid diseasesCurrent smokingHIV infection