2012
Cerebrospinal fluid levels of glutamate and corticotropin releasing hormone in major depression before and after treatment
Garakani A, Martinez JM, Yehuda R, Gorman JM. Cerebrospinal fluid levels of glutamate and corticotropin releasing hormone in major depression before and after treatment. Journal Of Affective Disorders 2012, 146: 262-265. PMID: 22840611, DOI: 10.1016/j.jad.2012.06.037.Peer-Reviewed Original Research
2011
PROINFLAMMATORY AND “RESILIENCY” PROTEINS IN THE CSF OF PATIENTS WITH MAJOR DEPRESSION
Martinez JM, Garakani A, Yehuda R, Gorman JM. PROINFLAMMATORY AND “RESILIENCY” PROTEINS IN THE CSF OF PATIENTS WITH MAJOR DEPRESSION. Depression And Anxiety 2011, 29: 32-38. PMID: 21898706, DOI: 10.1002/da.20876.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntidepressive Agents, Second-GenerationBrain-Derived Neurotrophic FactorCyclohexanolsDepressive Disorder, MajorFemaleHumansInflammationInflammation MediatorsInterleukin-1Interleukin-6MaleMiddle AgedNeuropeptide YSeverity of Illness IndexTumor Necrosis Factor-alphaUp-RegulationVenlafaxine HydrochlorideConceptsInflammatory cytokinesDepressed patientsHealthy controlsMajor depressionCSF cytokine levelsCSF of patientsCerebrospinal fluid levelsLumbar puncture procedureNormal comparison groupInflammatory hypothesisNPY concentrationsNPY levelsCytokine levelsIL-6Lumbar punctureClinical severityTreatment protocolIL-1CSF samplesPatientsNeuroprotective peptideFluid levelsSuicidal ideationPuncture procedureSmall sample size