2024
Antipsychotic agents in anxiety disorders: An umbrella review
Garakani A, Buono F, Salehi M, Funaro M, Klimowicz A, Sharma H, Faria C, Larkin K, Freire R. Antipsychotic agents in anxiety disorders: An umbrella review. Acta Psychiatrica Scandinavica 2024, 149: 295-312. PMID: 38382649, DOI: 10.1111/acps.13669.Peer-Reviewed Original ResearchSecond-generation antipsychoticsFirst-generation antipsychoticsGeneralized anxiety disorderStudies of antipsychoticsAnxiety disordersAntipsychotic agentsEfficacy of first-generation antipsychoticsTreatment of anxiety disordersEfficacy of antipsychotic agentsMeta-analysesAntidepressant treatmentNonantipsychotic medicationsAntipsychoticsFirst-line treatmentAnxietyComparing monotherapyUmbrella reviewDisordersQuetiapineSystematic reviewSide effectsAMSTAR-2Off-labelAPA PsycInfoCINAHL Complete
2022
An umbrella review on the use of antipsychotics in anxiety disorders: A registered report protocol
Garakani A, Freire RC, Buono FD, Thom RP, Larkin K, Funaro MC, Salehi M, Perez-Rodriguez MM. An umbrella review on the use of antipsychotics in anxiety disorders: A registered report protocol. PLOS ONE 2022, 17: e0269772. PMID: 35709149, PMCID: PMC9202921, DOI: 10.1371/journal.pone.0269772.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSelective serotonin reuptake inhibitorsSerotonin-norepinephrine reuptake inhibitorsUse of antipsychoticsLong-term riskAnxiety disordersReuptake inhibitorsUmbrella reviewSide effectsPanic disorderSystematic reviewNon-antipsychotic medicationsUse of quetiapineFirst-line treatmentSerotonin reuptake inhibitorsNorepinephrine reuptake inhibitorsEvidence of efficacyCommon psychiatric disordersTraditional pharmacologic treatmentTreatment of anxietyAdjunctive treatmentPharmacologic treatmentTricyclic antidepressantsAntipsychoticsPsychiatric disordersSocial anxiety disorder
2014
Advances in Psychopharmacology for Anxiety Disorders
Garakani A, Murrough J, Iosifescu D. Advances in Psychopharmacology for Anxiety Disorders. FOCUS The Journal Of Lifelong Learning In Psychiatry 2014, 12: 152-162. DOI: 10.1176/appi.focus.12.2.152.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSerotonin-norepinephrine reuptake inhibitorsSelective serotonin reuptake inhibitorsPosttraumatic stress disorderAnxiety disordersReuptake inhibitorsRelated conditionsGamma-aminobutyric acid (GABA) systemPharmacological treatment modalitiesFirst-line treatmentSerotonin reuptake inhibitorsNew pharmacotherapeutic approachesNorepinephrine reuptake inhibitorsVasopressin receptor antagonistsNovel treatment optionsPrevalent psychiatric disordersGlutamate modulatorsMedication classesCertain anxiety disordersNeuropeptide YTreatment modalitiesTreatment optionsNew drug developmentReceptor antagonistNew medicationsPharmacotherapeutic approaches
2010
The Pharmacological Treatment of Bipolar Disorder: The Question of Modern Advances
Hirschowitz J, Kolevzon A, Garakani A. The Pharmacological Treatment of Bipolar Disorder: The Question of Modern Advances. Harvard Review Of Psychiatry 2010, 18: 266-278. PMID: 20825264, DOI: 10.3109/10673229.2010.507042.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBipolar disorderGold standardMajor treatment guidelinesFirst-line treatmentMainstay of treatmentUse of lamotrigineTreatment of maniaBipolar maintenanceAtypical antipsychoticsTreatment guidelinesBipolar depressionMaintenance treatmentPharmacological treatmentFDA indicationMEDLINE searchNew agents