2016
Neuropsychiatric aspects of concussion
Radhakrishnan R, Garakani A, Gross LS, Goin MK, Pine J, Slaby AE, Sumner CR, Baron DA. Neuropsychiatric aspects of concussion. The Lancet Psychiatry 2016, 3: 1166-1175. PMID: 27889010, DOI: 10.1016/s2215-0366(16)30266-8.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTraumatic brain injuryBrain injuryDirect head traumaProspective clinical trialsEffective treatment interventionsNon-contact sportsHistory of lossHead traumaNeuropsychiatric symptomsPatient populationPsychiatric morbidityClinical trialsNeuropsychiatric aspectsTreatment responseElderly individualsContact sportsReliable biomarkersPsychiatric cliniciansTreatment interventionsClinical phenotypeConcussionMild formRelevant outcomesInjuryPatients
2010
Potential Psychiatric Applications of Metabotropic Glutamate Receptor Agonists and Antagonists
Krystal JH, Mathew SJ, D’Souza D, Garakani A, Gunduz-Bruce H, Charney DS. Potential Psychiatric Applications of Metabotropic Glutamate Receptor Agonists and Antagonists. CNS Drugs 2010, 24: 669-693. PMID: 20658799, DOI: 10.2165/11533230-000000000-00000.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPreliminary clinical trialsPositive allosteric modulatorsPsychiatric disordersClinical trialsAnimal modelsAllosteric modulatorsGroup II mGluR agonistGroup IMetabotropic glutamate receptor agonistAnxiety disordersPotential psychiatric applicationsGlutamate receptor agonistsMetabotropic glutamate receptorsTreatment of schizophreniaRole of glutamateForm of depressionMGluR agonistAntidepressant propertiesMGluR5 agonistReceptor agonistGlutamate receptorsMood disordersArea of schizophreniaPromising agentAgonists