Angiotensin‐(1–7) prevents cardiac remodeling during angiotensin II‐induced hypertension
Grobe J, Mecca A, Lingis M, Shenoy V, Bolton T, Machado J, Speth R, Raizada M, Katovich M. Angiotensin‐(1–7) prevents cardiac remodeling during angiotensin II‐induced hypertension. The FASEB Journal 2007, 21: a896-a897. DOI: 10.1096/fasebj.21.6.a896-d.Peer-Reviewed Original ResearchAng IICardiac remodelingBlood pressureInterstitial fibrosisMyocyte hypertrophyMale Sprague-Dawley ratsAng II infusionAnti-remodeling effectsEnd-organ damageRenin-angiotensin systemSprague-Dawley ratsII infusionAng receptorsAngiotensin receptorsAngiotensin IIMyocardial fibrosisRat modelMyocyte diameterEnzyme 2Receptor populationAngHypertensionFibrosisSignificant attenuationLentiviral delivery