Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice (117.2)
Wan W, Lim J, Lionakis M, Rivollier A, McDermott D, Kelsall B, Farber J, Murphy P. Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice (117.2). The Journal Of Immunology 2011, 186: 117.2-117.2. DOI: 10.4049/jimmunol.186.supp.117.2.Peer-Reviewed Original ResearchApoE-deficient miceCCR6-/- miceChemokine receptor CCR6Mice in vivoAtherosclerotic lesion areaApolipoprotein E-deficientApoE-/- miceReceptor CCR6Inflammatory monocytesLigand CCL20Monocyte functionCCR6Macrophage contentMonocyte levelsGenetic deletionPrimary monocytesLesional macrophagesWeeks of ageMouse monocytesMonocytesE deficiencyCCL20MiceMonocyte migrationCirculating blood