2017
C/EBPd enables the efficient extravasation of human CCR2+ MAIT cells
Zhang H, Lee C, Too L, Singh S, Tsang H, Kabat J, Singh T, Farber J. C/EBPd enables the efficient extravasation of human CCR2+ MAIT cells. The Journal Of Immunology 2017, 198: 143.10-143.10. DOI: 10.4049/jimmunol.198.supp.143.10.Peer-Reviewed Original ResearchMAIT cellsHuman umbilical vein endothelial cellsT cellsHuman mucosal-associated invariant T (MAIT) cellsMucosal-associated invariant T (MAIT) cellsBZIP transcription factorsResponse to pathogen challengeHuman MAIT cellsCD8+ T cellsExpression of FUT7Activated human umbilical vein endothelial cellsChemokine receptor CCR6Non-redundant roleSelectin ligandsSites of inflammationPathogen challengeTranscription factorsUmbilical vein endothelial cellsMR1-restrictedCD8+Receptor CCR6Efficient extravasationInflamed skinVein endothelial cellsChemokine receptors
2011
Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice (117.2)
Wan W, Lim J, Lionakis M, Rivollier A, McDermott D, Kelsall B, Farber J, Murphy P. Genetic deletion of chemokine receptor Ccr6 decreases atherogenesis in ApoE-deficient mice (117.2). The Journal Of Immunology 2011, 186: 117.2-117.2. DOI: 10.4049/jimmunol.186.supp.117.2.Peer-Reviewed Original ResearchApoE-deficient miceCCR6-/- miceChemokine receptor CCR6Mice in vivoAtherosclerotic lesion areaApolipoprotein E-deficientApoE-/- miceReceptor CCR6Inflammatory monocytesLigand CCL20Monocyte functionCCR6Macrophage contentMonocyte levelsGenetic deletionPrimary monocytesLesional macrophagesWeeks of ageMouse monocytesMonocytesE deficiencyCCL20MiceMonocyte migrationCirculating blood