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Patricia LoRusso, DO

Amy and Joseph Perella Professor of Medicine (Medical Oncology)
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Additional Titles

Chief, Experimental Therapeutics

Associate Cancer Center Director, Experimental Therapeutics

About

Titles

Amy and Joseph Perella Professor of Medicine (Medical Oncology)

Chief, Experimental Therapeutics; Associate Cancer Center Director, Experimental Therapeutics

Biography

Pat LoRusso brings more than 25 years of expertise in medical oncology, drug development, and early phase clinical trials. Prior to her Yale appointment, she served in numerous leadership roles at Wayne State University’s Barbara Karmanos Cancer Institute, most recently as director of the Phase I Clinical Trials Program and of the Eisenberg Center for Experimental Therapeutics.

Appointments

Other Departments & Organizations

Education & Training

MA
Yale University (2015)
Fellowship
Wayne State University (1988)
Residency
Riverside Osteopathic Hospital (1984)
Internship
Riverside Osteopathic Hospital (1982)
DO
Michigan State University (1981)
BS
Marygrove College (1977)

Research

Overview

LoRusso has served as co-chair of the National Cancer Institute (NCI) Cancer Therapy Evaluation Program (CTEP) Investigational Drug Steering Committee. She also served on the scientific committee of the American Association for Cancer Research (AACR), the education and scientific committees of the American Society of Clinical Oncology (ASCO), numerous peer-reviewed study sections, and NCI committees. She has garnered numerous awards, including the 1999 Heroes of Breast Cancer Award; 2004 Bennett J. Cohen Educational Leadership Award for Medical Research, 2008 NCI Michaele C. Christian Oncology Development Lectureship and Award; the 2014 Targeted Anticancer Therapies (TAT) Honorary Award; and will receive the 2014 Michigan State University Distinguished Alumni Award. She was recently honored as one of the 2014 Massachusetts General Hospital Cancer Center’s “One Hundred” individuals and organizations recognized for their dedication in making a difference in the fight against cancer. LoRusso is a former editor of Investigational New Drugs, is currently on the editorial board for Clinical Cancer Research, and is a reviewer for several journals. She has authored more than 200 articles on cancer research in peer-reviewed journals, and written multiple book chapters.

Interventional oncology; Liver cancer

Medical Subject Headings (MeSH)

Clinical Trial, Phase I; Regenerative Medicine

Research at a Glance

Yale Co-Authors

Frequent collaborators of Patricia LoRusso's published research.

Publications

2024

Clinical Trials

Current Trials

Academic Achievements & Community Involvement

  • honor

    Fellow

  • honor

    Joseph H. Burchenal Award for Outstanding Achievement in Clinical Cancer Research

Clinical Care

Overview

Oncologist Patricia LoRusso, DO, associate director of innovative medicine at Yale Medicine, has expertise in testing new treatments on patient volunteers who have advanced stages of cancer. Her passion is bringing research breakthroughs into the clinic to help patients with different types and stages of cancer.

The clinical trials at Yale Cancer Center offer access to experimental drugs that are sometimes a patient’s last and best hope, says Dr. LoRusso. Therapies that prove successful can advance through the U.S. Food and Drug Administration approval process. “Many of the drugs tested here will help generations of cancer patients,” says Dr. LoRusso. In her career, 14 cancer drugs she has performed clinical trials on, which she refers to as her “children,” have gone on to gain FDA approval.

Dr. LoRusso leads the Phase I clinical trials infusion center at Smilow Cancer Hospital at Yale New Haven. She infuses the center with a warm, team-focused approach that puts patients at the center of care. “We’re improving patients’ lives in Connecticut and beyond,” says Dr. LoRusso.

Clinical Specialties

Medical Oncology

Fact Sheets

Board Certifications

  • Medical Oncology

    Certification Organization
    American Osteopathic Board of Internal Medicine
    Original Certification Date
    1991
  • Internal Medicine

    Certification Organization
    American Osteopathic Board of Internal Medicine
    Original Certification Date
    1987

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Contacts

Academic Office Number
Appointment Number
Clinic Fax Number
Mailing Address

Yale Cancer Center

333 Cedar Street, WWW217

New Haven, CT 06520

United States

Locations

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