Thomas Bärnthaler
Assistant Professor AdjunctCards
About
Research
Publications
2024
The disrupted molecular circadian clock of monocytes and macrophages in allergic inflammation
Teppan J, Schwanzer J, Rittchen S, Bärnthaler T, Lindemann J, Nayak B, Reiter B, Luschnig P, Farzi A, Heinemann A, Sturm E. The disrupted molecular circadian clock of monocytes and macrophages in allergic inflammation. Frontiers In Immunology 2024, 15: 1408772. PMID: 38863703, PMCID: PMC11165079, DOI: 10.3389/fimmu.2024.1408772.Peer-Reviewed Original ResearchPolarized macrophagesHuman peripheral blood monocytesPrecision cut lung slicesMacrophage inflammatory proteinPeripheral blood monocytesChronic pulmonary diseaseInflammatory lung diseasesLung-protective propertiesTissue-resident macrophagesM2-polarized macrophagesMolecular circadian clockHuman monocyte-derived macrophagesHouse dust mite modelMonocyte-derived macrophagesCircadian protein CLOCKAllergic asthmaticsAllergic inflammationBlood monocytesEffector functionsLung diseaseInflammatory disordersMacrophage dysfunctionProtein expression patternsAllergic donorsTherapeutic approachesProfibrotic Role of GPR87 in Pulmonary Fibrosis
Khoury J, Ahangari F, Manning E, Justet A, barnthaler T, Adams T, Necola F, Alysandratos K, Beermann M, Kotton D, Kaminski N. Profibrotic Role of GPR87 in Pulmonary Fibrosis. 2024, a5183-a5183. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5183.Peer-Reviewed Original ResearchDevelopmental changes in lung function of mice are independent of sex as a biological variable
Bärnthaler T, Ramachandra A, Ebanks S, Guerrera N, Sharma L, Dela Cruz C, Humphrey J, Manning E. Developmental changes in lung function of mice are independent of sex as a biological variable. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2024, 326: l627-l637. PMID: 38375577, DOI: 10.1152/ajplung.00120.2023.Peer-Reviewed Original ResearchPulmonary function testsWeeks of ageStatic complianceMale miceInspiratory capacityLung functionBody weight-basedHuman lung pathologiesLung function of miceFemale C57BL/6J miceLung function parametersSex-dependent changesFunction of miceMeasures of lung functionIndependent of sexPreclinical modelsFemale miceC57BL/6J miceLung pathologyFunction testsMiceWeight-basedLungLung disease researchWeeks
2023
HDL-Related Parameters and COVID-19 Mortality: The Importance of HDL Function
Stadler J, Habisch H, Prüller F, Mangge H, Bärnthaler T, Kargl J, Pammer A, Holzer M, Meissl S, Rani A, Madl T, Marsche G. HDL-Related Parameters and COVID-19 Mortality: The Importance of HDL Function. Antioxidants 2023, 12: 2009. PMID: 38001862, PMCID: PMC10669705, DOI: 10.3390/antiox12112009.Peer-Reviewed Original ResearchCholesterol efflux capacityCOVID-19 mortalityCOVID-19 infectionHigh-density lipoprotein cholesterol levelsSARS-CoV-2 enters cellsCOVID-19-infected patientsCOVID-19Global public health challengeSignificant global public health challengeLipoprotein cholesterol levelsCOVID-19 groupPublic health challengeInflammatory markersHDL cholesterolHDL functionalityLipoprotein levelsSARS-CoV-2 coronavirusPneumonia patientsHDL functionCholesterol levelsHDL parametersEfflux capacityHDL phospholipidControl groupHDL