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- Breast, Colon, Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Phase I, Rectum, Stomach, ThyroidA Phase 1/2, First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors