This study investigates the unique psychosocial and support challenges faced by Black/African American and Hispanic/Latine women with early onset cancers, highlighting the need for culturally tailored interventions to improve care and support.
This study investigates how IDH1-mutant cancers develop resistance to PARP inhibitors through loss of end protection factors, 53BP1 and REV7, and shows that the drug cediranib can overcome this resistance, highlighting potential therapeutic strategies for improving cancer treatment outcomes.
This study investigates how socioeconomic and racial disparities impact access to immunotherapy for triple-negative breast cancer in the U.S., showing equitable access can improve outcomes for marginalized groups.
This study shows that tumor hypoxia silences the STING pathway, impairing immune response in cancer, and suggests targeting KDM1A to restore STING and enhance cancer therapy.