2025
The incidence and trends of diving-related spine injuries in the United States and risk factors associated with spinal cord injury
Seddio A, Jabbouri S, Vasudevan R, Gouzoulis M, Day W, Maloy G, Varthi A, Rubio D, Grauer J. The incidence and trends of diving-related spine injuries in the United States and risk factors associated with spinal cord injury. Spinal Cord 2025, 1-7. PMID: 40490487, DOI: 10.1038/s41393-025-01098-6.Peer-Reviewed Original ResearchEstimated annual percentage changeSpine injuriesSpinal cord injuryRisk factorsLumbar spineInjury prevention programsAnnual percentage changePublic health initiativesCord injuryCervical spine surgeryMultivariate logistic regressionLog-linear regressionUnique risk factorsHealth initiativesUnited StatesCervical spondylolisthesisElixhauser Comorbidity IndexCervical spinePrevention programsAdministrative datasetsLogistic regressionSpine surgeryPercentage changeCervical stenosisOlder ageSocioeconomic and demographic disparities in the impact of digestive diseases in the middle East and North Africa (MENA) region
Al Ta’ani O, Al-Ajlouni Y, Lahoud C, Almasaid S, Alhalalmeh Y, Oweis Z, Danpanichkul P, Baidoun A, Alsakarneh S, Dahiya D, Njei B. Socioeconomic and demographic disparities in the impact of digestive diseases in the middle East and North Africa (MENA) region. International Journal For Equity In Health 2025, 24: 85. PMID: 40148874, PMCID: PMC11951616, DOI: 10.1186/s12939-025-02448-9.Peer-Reviewed Original ResearchConceptsDisability-adjusted life yearsEstimated annual percentage changeSocio-demographic IndexAge-standardized incidence rateDisability-adjusted life year ratesGlobal Burden of DiseaseMiddle East and North AfricaGender Inequality IndexHuman Development IndexMiddle East and North Africa regionImpact of socioeconomic disparitiesIncidence rateAge-standardized mortalityAge-standardized ratesAnnual percentage changePercentage changeInfluence disease burdenBurden of DDBurden of diseasePublic health challengeHighest incidence rateSocioeconomic disparitiesDD incidenceTargeted interventionsNorth AfricaTrends in Preventable Hospitalization Rates for Children With or Without Observation Stay Data
Tian Y, Macy M, Hockenberry J, Holl J, Sabbatini A, Ackermann R, Kan K, Huang L, Raval M. Trends in Preventable Hospitalization Rates for Children With or Without Observation Stay Data. JAMA Network Open 2025, 8: e251533. PMID: 40126481, PMCID: PMC11933988, DOI: 10.1001/jamanetworkopen.2025.1533.Peer-Reviewed Original ResearchConceptsAmbulatory care sensitive conditionsPediatric ambulatory care sensitive conditionsPreventable hospitalization ratesAnnual percentage changeHospitalization ratesPercentage changeCross-sectional studyRetrospective cross-sectional studyHospital stay dataAmbulatory careInpatient dataMain OutcomesHealthcare costsSensitive conditionsInpatient-onlyObservation staysPediatric hospitalPatients aged 6Aged 6Quality indicatorsPatient statusHospitalDisease surveillanceCounty levelImpact of policies
2024
The impact of overweight and obesity on health outcomes in the United States from 1990 to 2021
Al Ta'ani O, Al‐Ajlouni Y, Aleyadeh W, Al‐Bitar F, Alsakarneh S, Saadeh A, Alhuneafat L, Njei B. The impact of overweight and obesity on health outcomes in the United States from 1990 to 2021. Diabetes Obesity And Metabolism 2024, 26: 5455-5465. PMID: 39261301, DOI: 10.1111/dom.15924.Peer-Reviewed Original ResearchConceptsDisability-adjusted life yearsAge-standardized death ratesSocio-demographic IndexBody mass indexHigher Body Mass IndexHealth outcomesDeath rateAge-standardized disability-adjusted life yearsComprehensive public health strategyGlobal Burden of Disease dataBurden of disease dataAge-standardized DALY rateAnnual percentage changePublic health strategiesSignificant public health challengeElevated body mass indexPublic health challengeUnited StatesImpact public healthHealth strategiesDALY ratesOlder adultsEnvironmental interventionsGlobal burdenHealth challengesEstimated Number of Children Who Lost a Parent to Drug Overdose in the US From 2011 to 2021
Jones C, Zhang K, Han B, Guy G, Losby J, Einstein E, Delphin-Rittmon M, Volkow N, Compton W. Estimated Number of Children Who Lost a Parent to Drug Overdose in the US From 2011 to 2021. JAMA Psychiatry 2024, 81: 789-796. PMID: 38717781, PMCID: PMC11079787, DOI: 10.1001/jamapsychiatry.2024.0810.Peer-Reviewed Original ResearchAverage annual percentage changeNon-HispanicRate of childrenNon-Hispanic Black individualsNon-Hispanic white individualsNational Vital Statistics SystemDrug overdoseCommunity-dwelling personsNon-Hispanic Black parentsAnnual percentage changeHealth care needsCommunity-dwelling childrenNational Survey on Drug Use and HealthVital Statistics SystemDrug Use and HealthParental ageOverdose deathsCross-sectional studyAlaska Native individualsImpact of parental lossEthnic groupsCare needsDrug overdose deathsMain OutcomesWhite individualsEpidemiology, treatment and outcomes of primary renal sarcomas in adult patients
Uhlig J, Uhlig A, Deshpande H, Ströbel P, Trojan L, Lotz J, Hurwitz M, Hafez O, Humphrey P, Grünwald V, Kim H. Epidemiology, treatment and outcomes of primary renal sarcomas in adult patients. Scientific Reports 2024, 14: 10038. PMID: 38693188, PMCID: PMC11063157, DOI: 10.1038/s41598-024-60174-8.Peer-Reviewed Original ResearchConceptsAnnual age-adjusted incidence ratesRenal sarcomaOverall survivalAdult patientsSurgical resectionAverage annual percentage changeDistant metastasisClinical presentationOverall survival of adult patientsAbsence of tumor necrosisSensitive to systemic therapySurvival of adult patientsNegative surgical marginsCornerstone of therapyMalignant rhabdoid tumorLower T stagePrimary renal sarcomaAssociated with younger ageAge-adjusted incidence ratesNCDB databaseLonger OSSurgical marginsSystemic therapyAnnual percentage changeRenal malignancyGender inequality and burden of orofacial clefts in the Eastern Mediterranean region: findings from global burden of disease study 1990–2019
Nabavizadeh S, Mootz J, Nadjmi N, Massenburg B, Khoshnood K, Shojaeefard E, Vardanjani H. Gender inequality and burden of orofacial clefts in the Eastern Mediterranean region: findings from global burden of disease study 1990–2019. BMC Pediatrics 2024, 24: 76. PMID: 38262976, PMCID: PMC10804627, DOI: 10.1186/s12887-024-04569-6.Peer-Reviewed Original ResearchConceptsBurden of orofacial cleftsDisability-adjusted life yearsEstimated annual percentage changeEastern Mediterranean RegionSocio-demographic IndexGender Inequality IndexGlobal burdenAssociated with disability-adjusted life yearsGlobal Burden of Disease StudyOrofacial cleftsDisability-adjusted life year ratesBurden of Disease StudyGlobal Burden of Disease databaseAnnual percentage changeAge-specific prevalence ratesMiddle-income countriesGender inequalityHuman Development IndexHealthcare servicesOrofacial cleft prevalencePotential confoundersSocio-DemographicResultsIn 2019Life yearsBackgroundGender inequalityBreast cancer incidence trends in Golestan, Iran: An age-period-cohort analysis by ethnic region, 2004-2018
Ghasemi-Kebria F, Fazel A, Semnani S, Etemadi A, Naeimi-Tabiei M, Hasanpour-Heidari S, Salamat F, Jafari-Delouie N, Sedaghat S, Sadeghzadeh H, Akbari M, Mehrjerdian M, Weiderpass E, Roshandel G, Bray F, Malekzadeh R. Breast cancer incidence trends in Golestan, Iran: An age-period-cohort analysis by ethnic region, 2004-2018. Cancer Epidemiology 2024, 89: 102525. PMID: 38228040, DOI: 10.1016/j.canep.2024.102525.Peer-Reviewed Original ResearchAge-standardized incidence rateAge-period-cohortIncidence rate ratiosAge-period-cohort analysisIncidence trendsCalculated age-standardized incidence ratesBreast cancer incidence trendsTrends of breast cancerCohort effectsNon-linear cohort effectsIncidence rateFemale breast cancer casesCancer incidence trendsBreast cancer incidenceAnnual percentage changeIncreased IRRsRural areasBreast cancer casesBreast cancerCancer incidenceDiagnosis yearReproductive factorsBirth cohortCancer casesRate ratios
2023
Temporal trends in mortality of aortic dissection and rupture in the UK, Japan, the USA and Canada
Hibino M, Verma S, Jarret C, Shimamura J, Verma R, Hibino H, Baeza C, Aune D, Yanagawa B, Usui A, Nienaber C, Pelletier M. Temporal trends in mortality of aortic dissection and rupture in the UK, Japan, the USA and Canada. Heart 2023, 110: 331-336. PMID: 37648437, DOI: 10.1136/heartjnl-2023-323042.Peer-Reviewed Original ResearchConceptsAge-standardised mortality ratesAge-standardised mortalityJoinpoint regressionAortic dissectionWHO Mortality DatabaseCompare mortality trendsAnnual percentage changeMortality rateStudy periodAortic ruptureMortality trendsMortality DatabaseMortality of aortic dissectionAortic aneurysm rupturePercentage changeJoinpointTemporal trendsAortic emergenciesLower mortalityClinical outcomesAneurysm ruptureMortalityDissectionCanadaUKHospitalization Trends and Outcomes of Eosinophilic Esophagitis in the United States: A Decade-Long Nationwide Analysis
Kwei-Nsoro R, Ojemolon P, Attar B, Shaka H, Zarza-Gulino P, Asare M, Annor E, Mba B. Hospitalization Trends and Outcomes of Eosinophilic Esophagitis in the United States: A Decade-Long Nationwide Analysis. Cureus 2023, 15: e44315. PMID: 37779798, PMCID: PMC10536399, DOI: 10.7759/cureus.44315.Peer-Reviewed Original ResearchTotal hospital chargesNational Inpatient SampleLength of stayJoinpoint regression analysisPrevalence ratesEosinophilic esophagitisHospitalization trendsStudy periodMortality ratePrevalence of EoEInflammatory bowel diseaseAnnual percentage changeAverage prevalence rateRegression analysisHospital-specific variablesPatient demographicsBowel diseaseHospital chargesInpatient DatabaseInpatient SampleMale genderEsophageal mucosaEsophageal diseaseHospitalizationNationwide analysisMortality trends of aortic stenosis in high-income countries from 2000 to 2020
Hibino M, Pandey A, Hibino H, Verma R, Aune D, Yanagawa B, Takami Y, Bhatt D, Attizzani G, Pelletier M, Verma S. Mortality trends of aortic stenosis in high-income countries from 2000 to 2020. Heart 2023, 109: 1473-1478. PMID: 37208159, DOI: 10.1136/heartjnl-2023-322397.Peer-Reviewed Original ResearchConceptsAge-standardised mortality ratesAge-specific mortality ratesMortality trendsCrude mortality rateHigh-income countriesJoinpoint regressionCalculate age-specific mortality ratesMortality rateWHO Mortality DatabaseAnnual percentage changeYounger age groupsMortality DatabaseAortic stenosisPercentage changeJoinpointAge groupsMortalityPersonsAustraliaDecreasing trendYearsCountriesObservation periodStenosisWHOThe global, regional, and national burden of inflammatory bowel diseases, 1990–2019: A systematic analysis for the global burden of disease study 2019
Park J, Jeong G, Song M, Yon D, Lee S, Koyanagi A, Jacob L, Kostev K, Dragioti E, Radua J, Cheon J, Shin J, Smith L. The global, regional, and national burden of inflammatory bowel diseases, 1990–2019: A systematic analysis for the global burden of disease study 2019. Digestive And Liver Disease 2023, 55: 1352-1359. PMID: 37137806, DOI: 10.1016/j.dld.2023.04.003.Peer-Reviewed Original ResearchConceptsAge-standardized prevalence rateDisability-adjusted life yearsPrevalence ratesAge-standardized death ratesGlobal burdenBurden of inflammatory bowel diseaseEpidemiology of inflammatory bowel diseaseGlobal Burden of DiseaseHighest age-standardized prevalence ratesAnnual percentage changeHigh-income Asia PacificInflammatory bowel diseaseRisk Factors StudyDeath rateBurden of diseasePrevalence of inflammatory bowel diseaseYears of lifeHigher socioeconomic indexGBD studyCrude prevalenceNational burdenSocioeconomic indexLife yearsFactor studiesDisease StudyIncreasing Use of Cannabis for Medical Purposes Among U.S. Residents, 2013–2020
Rhee T, Rosenheck R. Increasing Use of Cannabis for Medical Purposes Among U.S. Residents, 2013–2020. American Journal Of Preventive Medicine 2023, 65: 528-533. PMID: 36918131, PMCID: PMC10440227, DOI: 10.1016/j.amepre.2023.03.005.Peer-Reviewed Original ResearchConceptsMedical cannabis useAverage annual percentage changeAnnual percentage changeUse of cannabisCannabis useClinical subgroupsPercentage changeMultivariable-adjusted modelsCorrelates of cannabisSimilar significant increaseMedical cannabisDrug useDistrict of ColumbiaCannabisMedical purposesNationwide increaseSignificant increaseNational surveyDichotomous questionsU.S. residentsSubgroupsTemporal trendsAtrial fibrillation/atrial flutter related mortality trends in the US population 2010–2020: Regional, racial, sex variations
Ghajar A, Essa M, DeLago A, Parvez A, Aryan Z, Shalhoub J, Hammond‐Haley M, Hartley A, Sargsyan V, Salciccioli J, Faridi K, Nazarian S, Philips B. Atrial fibrillation/atrial flutter related mortality trends in the US population 2010–2020: Regional, racial, sex variations. Pacing And Clinical Electrophysiology 2023, 46: 519-525. PMID: 36527193, DOI: 10.1111/pace.14643.Peer-Reviewed Original ResearchConceptsAF/AFLCause of deathAnnual percentage changeMortality rateAtrial fibrillation/atrial flutterMortality trendsUnderlying causeNon-Hispanic White peopleEpidemiologic Research databaseNon-Hispanic black malesNon-Hispanic black peopleHigh mortality rateJoinpoint regression analysisTotal US populationPrevention WideBlack mortality ratesAtrial flutterObservational studyUrbanization statusResearch DatabaseUS populationDisease controlPercentage changeContributing causeMortality
2021
Trends in Precancerous Cervical Lesions by Area-Based Measures of Poverty, Race, and Ethnicity, Connecticut, 2008-2018
Brackney MM, Weinberger DM, Higgins K, Meek J, Niccolai LM. Trends in Precancerous Cervical Lesions by Area-Based Measures of Poverty, Race, and Ethnicity, Connecticut, 2008-2018. Public Health Reports 2021, 137: 1146-1152. PMID: 34727517, PMCID: PMC9574305, DOI: 10.1177/00333549211056300.Peer-Reviewed Original ResearchConceptsPrecancerous cervical lesionsAverage annual percentage changeCervical lesionsArea-based measuresPublic Health Disparities Geocoding ProjectAge groupsHuman papillomavirus vaccinationJoinpoint regression softwareAnnual percentage changeActive surveillance systemHPV vaccinationPapillomavirus vaccinationBody of evidenceIncidence rateSociodemographic characteristicsLesionsYoung womenAnnual declineIncidence dataPercentage changeCut pointsWomenVaccinationCensus tract levelSurveillance systemHepatocellular carcinoma incidence at national and provincial levels in Iran from 2000 to 2016: A meta-regression analysis
Fattahi N, Rezaei N, Asadi-Lari M, Yousefi M, Madadi Z, Gohari K, Sheidaei A, Mohammadi E, Rezaei N, Parsaeian M, Kompani F, Farzadfar F. Hepatocellular carcinoma incidence at national and provincial levels in Iran from 2000 to 2016: A meta-regression analysis. PLOS ONE 2021, 16: e0245468. PMID: 33481849, PMCID: PMC7822534, DOI: 10.1371/journal.pone.0245468.Peer-Reviewed Original ResearchConceptsAge-standardized incidence rateHepatocellular carcinoma incidenceIncidence rateRandom intercept mixed effects modelCancer incidence dataAnnual percentage changeIncidence of hepatocellular carcinomaRisk factor profileHepatocellular carcinoma incidence ratesAge groupsHepatocellular carcinomaHigh-risk populationCancer RegistryCancer incidenceMeta-regression analysisHealth plannersGeographical misalignmentYears of ageFactor profileIncidence dataMixed effects modelsPercentage changeScreening strategiesEpidemiological incidenceCarcinoma incidence
2019
962. Trends in Cervical Pre-cancers by Race and Ethnicity During the Human Papillomavirus Vaccine Era, HPV Vaccine Impact Monitoring Project (HPV-IMPACT), United States, 2008–2016
Gargano J, Lewis R, Hunt H, McClung N, Bennett N, Griffin M, Niccolai L, Park I, Powell M, Brackney M, Scahill M, Pemmaraju M, Fink D, Ehlers S, Cleveland A, Unger E, Markowitz L. 962. Trends in Cervical Pre-cancers by Race and Ethnicity During the Human Papillomavirus Vaccine Era, HPV Vaccine Impact Monitoring Project (HPV-IMPACT), United States, 2008–2016. Open Forum Infectious Diseases 2019, 6: s29-s29. PMCID: PMC6809029, DOI: 10.1093/ofid/ofz359.064.Peer-Reviewed Original ResearchAverage annual percentage changeCervical intraepithelial neoplasiaRace/ethnicityVaccine eraYear oldsNH blacksNH whitesHuman papillomavirus vaccine introductionActive population-based surveillanceHPV vaccine eraPopulation-based surveillanceConfidence intervalsAnnual percentage changeSignificant declineScreened womenVaccine impactRace/ethnicity dataCervical cancerIntraepithelial neoplasiaVaccine introductionCIN2Hispanic womenJoinpoint softwareSitu casesAge groupsTrends of admissions and case fatality rates among medical in-patients at a tertiary hospital in Uganda; A four-year retrospective study
Kalyesubula R, Mutyaba I, Rabin T, Andia-Biraro I, Alupo P, Kimuli I, Nabirye S, Kagimu M, Mayanja-Kizza H, Rastegar A, Kamya MR. Trends of admissions and case fatality rates among medical in-patients at a tertiary hospital in Uganda; A four-year retrospective study. PLOS ONE 2019, 14: e0216060. PMID: 31086371, PMCID: PMC6516645, DOI: 10.1371/journal.pone.0216060.Peer-Reviewed Original ResearchConceptsTrend of admissionsCase fatality rateAnnual percentage changeHIV/AIDSFatality rateMedical wardsDual burdenFour-year retrospective studyHigh case fatality ratePercentage changeNon-TB pneumoniaChronic kidney diseaseDate of dischargeCause of hospitalizationMajority of patientsProportion of hospitalizationsDate of admissionProportion of admissionsRisk of deathCause of morbidityAdult medical wardsDate of deathNon-communicable diseasesNon-infectious diseasesHealth system improvementTrends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014)
Inampudi C, Akintoye E, Bengaluru Jayanna M, Asleh R, Briasouli A, Alvarez P, Briasoulis A. Trends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014). Journal Of Cardiac Failure 2019, 25: 524-533. PMID: 30844441, DOI: 10.1016/j.cardfail.2019.02.020.Peer-Reviewed Original ResearchConceptsLength of stayEnd-stage renal disease patientsHF admissionsRenal disease patientsHospital mortalityNonroutine dischargeHeart failureESRD patientsDisease patientsStudy periodAnnual national ratesHF admission ratesPrevalence of comorbiditiesIn-Hospital MortalityNational Inpatient SampleCost of hospitalizationAnnual percentage changeYears of ageHF hospitalizationSecondary admissionsAdmission diagnosisComorbidity prevalencePeritoneal dialysisSubgroup analysisInpatient Sample
2018
Trends in Heart failure Hospitalization, In-hospital Mortality, Length of Stay and Disposition, Among ESRD patients on Dialysis (2001-2014)
Inampudi C, Akintoye E, Alvarez P, Bhama J, Briasoulis A. Trends in Heart failure Hospitalization, In-hospital Mortality, Length of Stay and Disposition, Among ESRD patients on Dialysis (2001-2014). Journal Of Cardiac Failure 2018, 24: s104. DOI: 10.1016/j.cardfail.2018.07.393.Peer-Reviewed Original ResearchLength of stayEnd-stage renal diseasePrimary HF admissionsHospital mortalityESRD patientsHeart failureHF admissionsEnd-stage renal disease patientsStage renal disease patientsAnnual national ratesPrimary HF hospitalizationsHeart failure hospitalizationRenal disease patientsBackground Cardiovascular diseaseNational Inpatient SampleRate of admissionAnnual percentage changeHF hospitalizationFailure hospitalizationHome dischargeRenal diseaseDisease patientsInpatient SampleCardiovascular diseaseCommon cause
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