2025
Single-Pedicled, Supercharged, or Bi-Pedicled? A Multi-Institutional Outcome Comparison of Pedicled TRAM Flap for Autologous Breast Reconstruction
Knoedler S, Matar D, Schaschinger T, Boroumand S, Tsolakidis S, Könneker S, Orgill D, Panayi A, Kim B. Single-Pedicled, Supercharged, or Bi-Pedicled? A Multi-Institutional Outcome Comparison of Pedicled TRAM Flap for Autologous Breast Reconstruction. Clinical Breast Cancer 2025 PMID: 40319006, DOI: 10.1016/j.clbc.2025.03.022.Peer-Reviewed Original ResearchRisk of medical complicationsHigher ASA classTRAM flapMedical complicationsSingle-pedicleASA classBreast reconstructionHigher BMIPedicled TRAM flap breast reconstructionAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseIncreased likelihood of reoperationNational Surgical Quality Improvement Program databaseHigher risk of medical complicationsQuality Improvement Program databaseTRAM flap breast reconstructionTRAM flap reconstructionFlap breast reconstructionPedicled TRAM flapAutologous breast reconstructionLikelihood of reoperationBi-pedicledComparison of outcomesFlap reconstructionSurgical complicationsChanging life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021
Collaborators G, Steel N, Bauer-Staeb C, Ford J, Abbafati C, Abdalla M, Abdelkader A, Abdi P, Zuñiga R, Abiodun O, Abolhassani H, Abu-Gharbieh E, Abukhadijah H, Abu-Zaid A, Addo I, Addolorato G, Adekanmbi V, Adetunji J, Adeyeoluwa T, Agardh E, Agyemang-Duah W, Ahmad D, Ahmed A, Ahmed A, Ahmed S, Akinosoglou K, Akkaif M, Al Awaidy S, Al Hasan S, Al Zaabi O, Aldridge R, Algammal A, Al-Gheethi A, Ali A, Ali M, Ali S, Ali W, Alicandro G, Alif M, Al-Jumaily A, Allebeck P, Alrawashdeh A, Al-Rifai R, Alsabri M, Alshahrani N, Aluh D, Al-Wardat M, Al-Zyoud W, Amiri S, Anderlini D, Andrei C, Anil A, Anvari S, Anyasodor A, Appiah S, Aquilano M, Arabloo J, Arafat M, Areda D, Aremu A, Armani K, Armocida B, Ärnlöv J, Asaduzzaman M, Astell-Burt T, Aujayeb A, Ausloos M, Azadnajafabad S, Aziz S, Azzam A, Babu G, Badache A, Badiye A, Bahramian S, Baig A, Baker J, Bansal H, Bärnighausen T, Barone M, Barrow A, Barteit S, Bashir S, Bashiru H, Basso J, Bastan M, Basu S, Batra K, Bauckneht M, Baune B, Beghi M, Beiranvand M, Béjot Y, Bell M, Bello O, Belo L, Beloukas A, Beneke A, Bettencourt P, Bhagavathula A, Bhala N, Bhaskar S, Bisulli F, Bjørge T, Bodunrin A, Carvajal A, Bouaoud S, Brayne C, Brenner H, Briggs A, Briko N, Bugiardini R, Buonsenso D, Busse R, Bustanji Y, dos Santos F, Barsbay M, Capodici A, Carreras G, Carugno A, Carvalho F, Carvalho M, Castaldelli-Maia J, Castelpietra G, Catapano A, Cattaruzza M, Cegolon L, Cenko E, Cerin E, Cerrai S, Chaudhary A, Chong B, Choudhari S, Chu D, Chukwu I, Chung S, Cioffi I, Conde J, Cortese S, Couto R, Criqui M, Cruz-Martins N, Dadras O, Dallat M, D'Amico E, D'Anna L, Darcho S, Dargan P, Das S, de la Torre-Luque A, Del Bo' C, Demetriades A, Dervenis N, Devleesschauwer B, Dhali A, Dhama K, Dianatinasab M, Diaz M, Dongarwar D, D'Oria M, Doshi O, Dowou R, Duraisamy S, Durojaiye O, Dziedzic A, Edvardsson D, Edvardsson K, Eikemo T, Ekholuenetale M, Ekundayo T, Arab R, Elgar F, Elhadi M, Eltaha C, Esposito F, Fabin N, Fagbamigbe A, Fagbule O, Fakhri-Demeshghieh A, Falzone L, Farinha C, Faris P, Fasina F, Fazeli P, Fazylov T, Feizkhah A, Fekadu G, Feng X, Fereshtehnejad S, Ferrante D, Ferrara P, Ferreira N, Fetensa G, Fischer F, Fonzo M, Fornari A, Fortuna D, Rodrigues C, Foschi M, Fox S, Freitas A, Fukumoto T, Gadanya M, Gallus S, Galluzzo L, Ganesan B, Ganiyani M, Gao X, Garcia-Gordillo M, Gazzelloni F, Gebregergis M, Gebremeskel T, Ghadimi D, Ghailan K, Ghith N, Gholami E, Gialluisi A, Gill P, Gillam T, Giussani G, Glasbey J, Glenn S, Göbölös L, Goldust M, Golechha M, Goleij P, Golinelli D, Gorini G, Graham S, Griebler R, Grover A, Guicciardi S, Gunturu S, Gupta V, Gutiérrez-Murillo R, Habteyohannes A, Haep N, Nam N, Haller S, Hamoudi R, Handanagic S, Haro J, Hasani H, Hasnain S, Havmoeller R, Hay S, Hebert J, Heibati B, Hilderink H, Hiraike Y, Hoan N, Hosseinzadeh M, Hostiuc S, Hoven H, Hu C, Huang J, Hughes A, Hultström M, Hushmandi K, Hussain J, Hussain M, Ikiroma A, Inok A, Islam R, Islam M, Isola G, Iyer M, Jacob L, Jahrami H, Jairoun A, Jaka S, Jakovljevic M, Jawaid T, Jeswani B, Jonas J, Joshua C, Kaambwa B, Kabir Z, Kadir D, Kamath R, Kanmodi K, Kapoor N, Karakasis P, Karanikolos M, Karaye I, Kauppila J, Kazemian S, Kesse-Guyot E, Khamesipour F, Khan A, Khanmohammadi S, Khatab K, Khatatbeh M, Khormali M, Khosla A, Khosravi M, Khosrowjerdi M, Khubchandani J, Kim K, Kim M, Kisa A, Kisa S, Knudsen A, Koren G, Kuddus A, Kuitunen I, Kulimbet M, Kumar R, Kunutsor S, Kurmi O, Kusuma D, Kytö V, La Vecchia C, Lai H, Lallukka T, Lanfranchi F, Langguth B, Laplante-Lévesque A, Larson H, Larsson A, Lee M, Lee P, Lee S, Lee W, Lindholm D, Linehan C, Liu X, Llanaj E, López-Gil J, Lorkowski S, Lucchetti G, Lugo A, Lunevicius R, Luo L, Amin H, Feei Z, Machairas N, Machoy M, Malhotra K, Malik A, Mansour A, Manu E, Marateb H, Martini D, Martorell M, Marzo R, Mathangasinghe Y, Mathur M, Matozinhos F, Maude R, Maugeri A, May J, Mayeli M, Mazidi M, McKee M, Mechili E, Mehravar S, Meto T, Meles H, Mentis A, Meretoja A, Meretoja T, Mettananda S, Micha G, Michalek I, Miller T, Minervini G, Mirijello A, Mocciaro G, Fard A, Mohamed J, Mohamed N, Mohammadian-Hafshejani A, Mohammed S, Monasta L, Mondello S, Moni M, Moraga P, Morawska L, Mossie T, Motappa R, Mubarik S, Muccioli L, Mueller U, Mughal F, Mulita F, Munblit D, Munkhsaikhan Y, Murray C, Naghavi M, Naghavi P, Naik G, Najdaghi S, Naqvi A, Davani D, Nascimento G, Naser A, Nashwan A, Nauman J, Navaratna S, Nazri-Panjaki A, Nejjari C, Nena E, Netsere H, Nguyen A, Nguyen P, Nguyen V, Nnyanzi L, Noor S, Nouri M, Nugen F, Nurchis M, Nzoputam O, Oancea B, O'Donnell M, Oduro M, Ogundijo O, Ogunsakin R, Okeke S, Okonji O, Olagunju A, Oliver S, Olufadewa I, Ortiz A, Owolabi M, A M, Padubidri J, Palma-Alvarez R, Panda S, Panda-Jonas S, Panos G, Panos L, Pantazopoulos I, Pardhan S, Parikh R, Passera R, Patil S, Patoulias D, Pawar S, Pensato U, Pereira G, Perico N, Perna S, Petermann-Rocha F, Pham H, Philip A, Pierannunzio D, Pigeolet M, Pisoni E, Poddighe D, Poluru R, Postma M, Pradhan J, Pupillo E, Puvvula J, Raggi A, Rahman M, Rahman M, Raimondo D, Raimondo I, Ramasamy S, Ramazanu S, Rana R, Rao S, Rasella D, Rashid A, Rauniyar S, Rautalin I, Rawaf D, Rawaf S, Reddy M, Redwan E, Reifels L, Remuzzi G, Rezaeian M, Ribeiro A, Rijal A, Rodriguez J, Romoli M, Ronfani L, Root K, Rout H, Roy N, Russo M, Saad A, Sabet C, Dhingra M, Saeed U, Safari M, Safdarian, Saleh M, Salem M, Salum G, Samuel V, Samy A, Saravanan A, Saravi B, Sarkar C, Saulam J, Scarmeas N, Schaarschmidt B, Schinckus C, Schlaich M, Schmidt J, Schuermans A, Schumacher A, Schwendicke F, Schwinger C, Sepanlou S, Shafie M, Shahsavari H, Shaikh M, Shakil H, Sham S, Shamim M, Sharew N, Sharifan A, Shavandi A, Shenoy R, Shetty M, Shetty P, Shetty P, Shigematsu M, Shittu A, Shiue I, Shorofi S, Shrestha R, Shrestha R, Siddig E, Silva J, Silva L, Silva S, Singh P, Singh S, Sipilä J, Skryabina A, Sokhan A, Soraneh S, Soriano J, Soyiri I, Spartalis M, Steiropoulos P, Stockfelt L, Sun J, Sundström J, Sunkersing D, Sunnerhagen K, Swain C, Szarpak L, Y S, Damavandi P, Tabarés-Seisdedos R, Tabatabaei S, Tabche C, Tabibi R, Taiba J, Tanwar M, Tat N, Taveira N, Temsah M, Thayakaran R, Tiruye T, Touvier M, Tovani-Palone M, Tran J, Tran N, Tran T, Trico D, Tromans S, Tsermpini E, Car L, Tumurkhuu M, Ullah S, Unim B, Vaithinathan A, Valenti M, Van den Eynde J, Varga O, Vasankari T, Vellingiri B, Veroux M, Vervoort D, Villafañe J, Violante F, Vizzielli G, Vodden A, Vollset S, Vos T, Wafa H, Wang Y, Wassie E, Weerakoon K, Westerman R, Wickramasinghe N, Willeit P, Wojewodzic M, Wolf A, Wolfe C, Wyper G, Xu X, Yasufuku Y, Yaya S, Yezli S, YiÄŸit A, Yon D, Yu C, Zakham F, Zanghì A, Zastrozhin M, Zeariya M, Zhang L, Zhang Z, Zhong C, Zhu B, Ziafati M, Zielińska M, Zweck E, Zyoud S, Newton J. Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021. The Lancet Public Health 2025, 10: e172-e188. PMID: 39983748, PMCID: PMC11876102, DOI: 10.1016/s2468-2667(25)00009-x.Peer-Reviewed Original ResearchConceptsLow physical activityLife expectancy improvementsPhysical activityLife expectancyRisk factorsCardiovascular diseaseHigher BMIDeterminants of poor healthTobacco smokeCause-specific death ratesGlobal burdenGlobal Burden of Disease StudyBurden of Disease StudyGlobal Burden of DiseaseImprove population healthDecreasing exposure to tobacco smokeExposure to tobacco smokeAnnual life expectancyRisk Factors StudyCOVID-19 pandemicBurden of diseaseChanging life expectancyHigher alcohol useAnnual improvementInfluence life expectancy
2024
Vitamin D Levels in the United States: Temporal Trends (2011–2018) and Contemporary Associations with Sociodemographic Characteristics (2017–2018)
Subramanian A, Burrowes H, Rumph J, Wilkerson J, Jackson C, Jukic A. Vitamin D Levels in the United States: Temporal Trends (2011–2018) and Contemporary Associations with Sociodemographic Characteristics (2017–2018). Nutrients 2024, 16: 3414. PMID: 39408379, PMCID: PMC11478591, DOI: 10.3390/nu16193414.Peer-Reviewed Original ResearchConceptsNational Health and Nutrition Examination SurveyNon-Hispanic black femalesVitamin D levelsNational Health and Nutrition Examination Surveys survey cyclesHealth and Nutrition Examination SurveyNon-Hispanic blacksAssociated with larger decrementsNutrition Examination SurveyMedian 25(OH)DD levelsPredictors of 25(OH)D levelsMultivariate linear regressionExamination SurveyPrevalence of 25(OH)DSurvey cyclesWeighted medianLevels of 25(OH)DSociodemographic characteristicsVitamin D supplementationFemales of reproductive ageHigher BMILow-incomeIncreased BMIMexican AmericansVitamin D dataCharacterization of sleep apnea among a sample of adults from Samoa
Heinsberg L, Pomer A, Cade B, Carlson J, Naseri T, Reupena M, Viali S, Weeks D, McGarvey S, Redline S, Hawley N. Characterization of sleep apnea among a sample of adults from Samoa. Sleep Epidemiology 2024, 4: 100099. PMID: 39749350, PMCID: PMC11694763, DOI: 10.1016/j.sleepe.2024.100099.Peer-Reviewed Original ResearchApnea-hypopnea indexOxygen desaturation indexSleep apneaCharacteristics of sleep apneaSevere sleep apneaSleep apnea deviceObesity-risk alleleGeographic region of residenceType 2 diabetesInfluence sleep healthHypopnea indexDesaturation indexGlobal public health concernApneaHigher BMIRegion of residenceCircumference ratioMale sexMiddle-income countriesSample of adultsPublic health concernSamoan adultsBMISleep healthHealth concernMaladaptive health factors as potential mediators for the association between posttraumatic stress disorder and cardiovascular disease: A sex-stratified analysis in the U.S. adult population
Pierce S, Reynolds K, Sommer J, El-Gabalawy R, Pietrzak R, Sumner J, Mota N. Maladaptive health factors as potential mediators for the association between posttraumatic stress disorder and cardiovascular disease: A sex-stratified analysis in the U.S. adult population. Journal Of Psychiatric Research 2024, 177: 102-108. PMID: 39002531, DOI: 10.1016/j.jpsychires.2024.06.028.Peer-Reviewed Original ResearchHealth risk factorsPosttraumatic stress disorderRisk factorsPotential mediatorsCardiovascular diseaseLow physical activityCross-sectional surveyNatural effect modelsSex-stratified analysesU.S. adult populationCardiovascular disease riskStress disorderPhysical activityNational Epidemiologic SurveyLogistic regression analysisHealth factorsEvaluate health risk factorsU.S. adultsHigher BMICausal pathwaysPrevention strategiesEffects of posttraumatic stress disorderWave 3Adult populationSubstance useSmoking is not associated with wound complications in augmented urethroplasty: a NSQIP analysis
Cahill E, Islam R, Chua K, Balraj V, Boyle J, Patel H, Kaldany A, Doppalapudi S, Velez D, Tunuguntla H, Sterling J. Smoking is not associated with wound complications in augmented urethroplasty: a NSQIP analysis. International Urology And Nephrology 2024, 56: 3479-3484. PMID: 38811450, DOI: 10.1007/s11255-024-04085-7.Peer-Reviewed Original ResearchConceptsRisk factors associated with wound complicationsFactors associated with wound complicationsAssociated with wound complicationsAugmentation urethroplastyWound complicationsMultivariate logistic regressionMethodsThe National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databasePredictors of wound complicationsQuality Improvement Program databaseAssociated with increased wound complicationsPrimary anastomosis urethroplastyLogistic regressionLonger operative timeNo significant differenceMale patientsThirty-dayAugmented groupHigher BMISmoking historyUrethroplastyProgram databaseCurrent smokersComplicationsOperative time#2598 Risk of vascular access complications in haemodialysis patients initiating dialysis with arteriovenous fistula or arteriovenous graft
Willetts J, Usvyat L, Chaudhuri S, Niklason L, Maddux F. #2598 Risk of vascular access complications in haemodialysis patients initiating dialysis with arteriovenous fistula or arteriovenous graft. Nephrology Dialysis Transplantation 2024, 39: gfae069-1550-2598. DOI: 10.1093/ndt/gfae069.1550.Peer-Reviewed Original ResearchVascular access complication ratesArteriovenous fistulaEnd-stage kidney diseaseArteriovenous graftsVA complicationsVascular accessIn-Center HemodialysisInitial VAComorbid conditionsDuration of follow-upAssociated with increased riskComplication eventsHistory of myocardial infarctionCongestive heart failureVascular access complicationsDiabetic ptsRisk of vascular access complicationsComplication rateDemographic characteristicsIncreased BMIDocumented thrombosisIn-Center Hemodialysis PatientsContinuous hemodialysisHigher BMIHaemodialysis patientsDietary inflammatory index after liver transplantation: Associated effects and long-term outcomes
Hott C, Santos B, Hebert J, Zhao L, Wirth M, Vilela E, Anastácio L. Dietary inflammatory index after liver transplantation: Associated effects and long-term outcomes. Clinical Nutrition ESPEN 2024, 61: 349-355. PMID: 38777454, DOI: 10.1016/j.clnesp.2024.04.001.Peer-Reviewed Original ResearchConceptsPro-inflammatory dietDietary inflammatory indexSerum LDL cholesterolClinical outcomesDII scoresInflammatory indexLiver transplantationLDL cholesterolFollow-upOccurrence of clinical outcomesLong-term follow-upYears of follow-upOccurrence of cardiovascular eventsDietary inflammatory potentialLong-term outcomesAssociated with steatosisPredictive of neoplasiaPatient ageHigher BMISmoking historyCardiovascular eventsInflammatory potentialPatientsTransplantationOutcomesIndications and outcomes of liver transplantation for liver tumors in the United States
Okumura K, Dhand A, Hanna K, Misawa R, Sogawa H, Veillette G, Nishida S. Indications and outcomes of liver transplantation for liver tumors in the United States. Surgery In Practice And Science 2024, 17: 100245. PMID: 39845637, PMCID: PMC11749412, DOI: 10.1016/j.sipas.2024.100245.Peer-Reviewed Original ResearchBile duct cancerLiver transplantationLiver tumorsHepatocellular carcinomaLT recipientsBenign tumorsSecondary tumorsDuct cancerMultivariate Cox regression analysisHighest prevalence of hepatitis COutcome of liver transplantationMultivariate Cox proportional-hazards modelUnited Network for Organ Sharing databaseOutcomes of LTPrevalence of hepatitis CKaplan-Meier methodOne-year survivalCox regression analysisCox proportional-hazards modelProportional-hazards modelNeuroendocrine tumorsSurvival outcomesHepatitis CHepatic tumorsHigher BMILongitudinal Patterns of Disordered Eating Behaviors in Children and Adolescents from the Brazilian High-Risk Cohort Study for Mental Conditions.
de Oliveira I, Fernandéz A, Salum G, Gadelha A, Pan P, Miguel E, Mograbi D, Bado P. Longitudinal Patterns of Disordered Eating Behaviors in Children and Adolescents from the Brazilian High-Risk Cohort Study for Mental Conditions. Brazilian Journal Of Psychiatry 2024 PMID: 39731576, DOI: 10.47626/1516-4446-2024-3867.Peer-Reviewed Original ResearchDisordered eating behaviorsInternalizing symptomsEating DisordersBrazilian High-Risk Cohort StudyPatterns of disordered eating behaviorBrazilian High-Risk CohortMajor depressive disorderHigh Risk Cohort StudyChild Behavior ChecklistHigh-risk cohortDimensional psychopathologyPsychopathological correlatesDepressive disorderPsychopathological diagnosisExternalizing behaviorsBehavior ChecklistDevelopmental trajectoriesEating groupDisorder screeningPsychopathologyEating behaviorsHigher BMIPercentage of individualsCohort studyEffective interventions
2023
Impact of BMI in Patients With Early Hormone Receptor–Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS Trial
Pfeiler G, Hlauschek D, Mayer E, Deutschmann C, Kacerovsky-Strobl S, Martin M, Meisel J, Zdenkowski N, Loibl S, Balic M, Park H, Prat A, Isaacs C, Bajetta E, Balko J, Bellet-Ezquerra M, Bliss J, Burstein H, Cardoso F, Fohler H, Foukakis T, Gelmon K, Goetz M, Haddad T, Iwata H, Jassem J, Lee S, Linderholm B, Los M, Mamounas E, Miller K, Morris P, Munzone E, Gal-Yam E, Ring A, Shepherd L, Singer C, Thomssen C, Tseng L, Valagussa P, Winer E, Wolff A, Zoppoli G, Machacek-Link J, Schurmans C, Huang X, Gauthier E, Fesl C, Dueck A, DeMichele A, Gnant M, Cameron D, El-Abed S, Rugo H, Steger G, Traina T, Werutsky G, Wolmark N. Impact of BMI in Patients With Early Hormone Receptor–Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS Trial. Journal Of Clinical Oncology 2023, 41: 5118-5130. PMID: 37556775, DOI: 10.1200/jco.23.00126.Peer-Reviewed Original ResearchConceptsImpact of BMIPALLAS trialBMI categoriesHigher BMIEarly hormone receptor-positive breast cancerHormone receptor-positive breast cancerReceptor-positive breast cancerAddition of palbociclibEfficacy of palbociclibEarly treatment discontinuationRelative dose intensityTreatment discontinuation ratesDisease-free survivalSide effect profileMultivariable logistic regressionBreast cancer riskSignificant decreaseNeutropenia ratesPalbociclib armEndocrine therapyTreatment discontinuationDiscontinuation ratesDose intensityEarly discontinuationNormal weight
2022
Infection risk in a real-world cohort of patients treated with long-term B-cell depletion for autoimmune neurologic disease
Peters J, Longbrake E. Infection risk in a real-world cohort of patients treated with long-term B-cell depletion for autoimmune neurologic disease. Multiple Sclerosis And Related Disorders 2022, 68: 104400. PMID: 36544307, PMCID: PMC10075342, DOI: 10.1016/j.msard.2022.104400.Peer-Reviewed Original ResearchConceptsLong-term B-cell depletionB-cell depletionReal-world cohortSevere infectionsTotal infectionsSingle-center observational studyEffective disease-modifying therapiesInfectious adverse effectsFormer smoking statusRisk of hospitalizationAutoimmune neurologic diseasesAutoimmune neurologic disordersDisease-modifying therapiesYears of treatmentRate of infectionLong-term useImmunologic changesLaboratory abnormalitiesClinical factorsSmoking statusHigher BMIMultiple sclerosisSerious infectionsNeurologic disordersFemale genderThe protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans
Hawley NL, Duckham RL, Carlson JC, Naseri T, Reupena MS, Lameko V, Pomer A, Wetzel A, Selu M, Lupematisila V, Unasa F, Vesi L, Fatu T, Unasa S, Faasalele‐Savusa K, Rivara AC, Russell E, Delany JP, Viali S, Kershaw EE, Minster RL, Weeks DE, McGarvey ST. The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans. Obesity 2022, 30: 2468-2476. PMID: 36284436, PMCID: PMC10111239, DOI: 10.1002/oby.23559.Peer-Reviewed Original ResearchConceptsFat-free massType 2 diabetesFat distributionProtective effectBody compositionFavorable body fat distributionDual-energy X-ray absorptiometry-derived body compositionBody fat distributionGreater fat-free massPercent body fatBody size/compositionAssociation of genotypesRs373863828 genotypeVisceral adiposityHigher BMIAdult SamoansRole of fatGreater BMILean massBody fatLower oddsParadoxical associationTissue-specific mechanismsA alleleDiabetesThe obesity paradox: Retinopathy, obesity, and circulating risk markers in youth with type 2 diabetes in the TODAY Study
Levitsky LL, Drews KL, Haymond M, Glubitosi-Klug RA, Katz L, Mititelu M, Tamborlane W, Tryggestad JB, Weinstock RS, Group T. The obesity paradox: Retinopathy, obesity, and circulating risk markers in youth with type 2 diabetes in the TODAY Study. Journal Of Diabetes And Its Complications 2022, 36: 108259. PMID: 36150365, DOI: 10.1016/j.jdiacomp.2022.108259.Peer-Reviewed Original ResearchConceptsNon-proliferative diabetic retinopathyType 2 diabetesHigh-sensitivity C-reactive proteinObesity paradoxInflammatory biomarkersHDL cholesterolLDL cholesterolInsulin-like growth factor binding protein 1Sensitivity C-reactive proteinGrowth factor binding protein 1Today StudyPresence of retinopathyRelationship of obesityC-reactive proteinPlasminogen activator inhibitor-1Tumor necrosis factor receptor 1Digital fundus photographsNecrosis factor receptor 1Activator inhibitor-1Factor receptor 1Higher BMIObese participantsRisk markersDiabetic retinopathyInterleukin-6CYP2D6 Genetic Variation and Antipsychotic-Induced Weight Gain: A Systematic Review and Meta-Analysis
Wannasuphoprasit Y, Andersen SE, Arranz MJ, Catalan R, Jurgens G, Kloosterboer SM, Rasmussen HB, Bhat A, Irizar H, Koller D, Polimanti R, Wang B, Zartaloudi E, Austin-Zimmerman I, Bramon E. CYP2D6 Genetic Variation and Antipsychotic-Induced Weight Gain: A Systematic Review and Meta-Analysis. Frontiers In Psychology 2022, 12: 768748. PMID: 35185676, PMCID: PMC8850377, DOI: 10.3389/fpsyg.2021.768748.Peer-Reviewed Original ResearchNormal metabolizersCross-sectional studyPoor metabolizersIntermediate metabolizersSystematic reviewCohort studyWeight gainAntipsychotic treatmentAntipsychotic-Induced Weight GainMost cross-sectional studiesLong-term antipsychoticsCYP2D6 genetic variationCYP2D6 poor metabolizersReduced life expectancyHigher BMIAntipsychotic medicationLiver enzymesClinical dataClinical utilityBMIPsychotic disordersMeta-analysisMetabolizersSignificant associationLarger study
2021
Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Hernáez Á, Rogne T, Skåra KH, Håberg SE, Page CM, Fraser A, Burgess S, Lawlor DA, Magnus MC. Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study. Human Reproduction 2021, 36: 3141-3151. PMID: 34668019, PMCID: PMC8600658, DOI: 10.1093/humrep/deab224.Peer-Reviewed Original ResearchConceptsCohort studyBMI valuesMendelian randomization analysisMultivariable regressionGreater oddsMultivariable logistic regression modelSTUDY FUNDING/COMPETINGProject number 262700Risk of subfertilityRandomization analysisBody mass indexChild Cohort StudyPARTICIPANTS/MATERIALSUK National InstituteNational InstituteROLE OF CHANCELogistic regression modelsSelf-reported informationAssisted reproduction technologyObese menObese womenHigher BMILower BMIMass indexUS National Institutes1108-P: Care Cascade Engagement and Characteristics of Diabetes Awareness in Adult Samoans in 2010 and 2018
RIVARA A, RUSSELL E, VIALI S, REUPENA M, NASERI T, POMER A, MINSTER R, WEEKS D, MCGARVEY S, HAWLEY N. 1108-P: Care Cascade Engagement and Characteristics of Diabetes Awareness in Adult Samoans in 2010 and 2018. Diabetes 2021, 70 DOI: 10.2337/db21-1108-p.Peer-Reviewed Original ResearchGlycemic controlMedication useDiabetes awarenessAdult SamoansUnmet needSocioeconomic positionCare cascadeLifestyle scoreDiabetes prevalenceHigher BMICare engagementDiabetes careHigher oddsDisease awarenessLower oddsGreater oddsLogistic regressionDiabetesDoctor's diagnosisTime pointsNational InstituteOddsGenetic variantsDiagnosisCareFactors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta‐analysis
Hahn JA, Murnane PM, Vittinghoff E, Muyindike WR, Emenyonu NI, Fatch R, Chamie G, Haberer JE, Francis JM, Kapiga S, Jacobson K, Myers B, Couture MC, DiClemente RJ, Brown JL, So-Armah K, Sulkowski M, Marcus GM, Woolf-King S, Cook RL, Richards VL, Molina P, Ferguson T, Welsh D, Piano MR, Phillips SA, Stewart S, Afshar M, Page K, McGinnis K, Fiellin DA, Justice AC, Bryant K, Saitz R. Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta‐analysis. Alcohol Clinical And Experimental Research 2021, 45: 1166-1187. PMID: 33837975, PMCID: PMC8254773, DOI: 10.1111/acer.14611.Peer-Reviewed Original ResearchConceptsIndividual participant dataUnhealthy alcohol useRace/ethnicitySelf-reported alcohol useAlcohol useBiologic variablesHigher oddsAlcohol consumptionBlood collectionAdvanced liver fibrosisUnhealthy alcohol consumptionIndividual patient dataAUDIT-C scoresAssociation of sexAfrican AmericansHigher BMILiver fibrosisEligible studiesHigher hemoglobinClinical careLower oddsAlcohol metabolitesParticipant dataPatient dataMixed effects modelsDoes non‐invasive blood pressure measurement increase the complications and decrease indwelling time of peripheral intravenous catheters: A cohort study
Tan Q, Zhao S, Li X, Gu B, Ni Z. Does non‐invasive blood pressure measurement increase the complications and decrease indwelling time of peripheral intravenous catheters: A cohort study. Journal Of Clinical Nursing 2021, 30: 2287-2292. PMID: 33829602, DOI: 10.1111/jocn.15751.Peer-Reviewed Original ResearchConceptsPeripheral intravenous cathetersRenal transplant recipientsNon-invasive blood pressure measurementBlood pressure measurementsIntravenous cathetersRisk factorsControl groupTransplant recipientsCohort studyObservation groupNon-invasive blood pressure monitoringNon-invasive blood pressure monitorKidney recipient patientsIncidence of complicationsIndependent risk factorIncidence of phlebitisBlood pressure monitoringCox regression modelRelative risk factorsBlood pressure monitorPerioperative periodHigher BMIClinical complicationsRisk regressionRecipient patientsHockey stick incision: a modified technique for chest wall masculinization
Junn A, Khetpal S, Smetona J, Dinis J, Hirschman A, Mozaffari MA, Singh A, Ching AH, Alperovich M, Lu X, Persing JA. Hockey stick incision: a modified technique for chest wall masculinization. Annals Of Translational Medicine 2021, 9: 600-600. PMID: 33987298, PMCID: PMC8105854, DOI: 10.21037/atm-20-7678.Peer-Reviewed Original ResearchChest wall masculinizationChest masculinization surgeryPatient satisfactionDouble-incision mastectomyClinical outcomesTransgender menFree nipple graft techniqueYale-New Haven HospitalComparable patient satisfactionPost-operative eventsRetrospective chart reviewEffective surgical techniquePost-operative outcomesBody mass indexLateral chest wallFree nipple graftBMI patientsChart reviewMass indexWound dehiscenceHigher BMINipple graftSurgical techniqueGraft techniqueChest wall
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