2020
Presentation and outcomes of carotid endarterectomy in active smokers
Kim TI, Zhang Y, Amin HP, Ochoa Chaar CI. Presentation and outcomes of carotid endarterectomy in active smokers. Journal Of Vascular Surgery 2020, 72: 1720-1727.e1. PMID: 32249043, DOI: 10.1016/j.jvs.2020.02.014.Peer-Reviewed Original ResearchConceptsCarotid endarterectomyRisk factorsWorse outcomesSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramChronic obstructive pulmonary diseaseSignificant modifiable risk factorSurgical Quality Improvement ProgramHigh anatomic riskOutcomes of patientsModifiable risk factorsObstructive pulmonary diseaseCarotid artery diseaseImportant risk factorLarge national databaseQuality Improvement ProgramActive smokingEmergent surgeryPreoperative characteristicsActive smokersArtery diseasePropensity matchingPulmonary diseaseSymptomatic presentationSmoking status
2016
Risk of Pregnancy-Associated Stroke Across Age Groups in New York State
Miller EC, Gatollari HJ, Too G, Boehme AK, Leffert L, Elkind MS, Willey JZ. Risk of Pregnancy-Associated Stroke Across Age Groups in New York State. JAMA Neurology 2016, 73: 1461-1467. PMID: 27775757, DOI: 10.1001/jamaneurol.2016.3774.Peer-Reviewed Original ResearchConceptsPregnancy-associated strokePregnant/postpartum womenRisk of strokeIncidence risk ratioRisk factorsPostpartum womenAge groupsNonpregnant womenStroke riskOlder womenCumulative riskAge-specific incidence ratiosPost partumCalendar year 2003Cerebral venous thrombosisStroke risk factorsTransient ischemic attackVascular risk factorsOverall median ageLogistic regression modelsActive smokingChronic hypertensionIschemic attackNPAS groupCerebrovascular events
2014
Active Smoking Is Associated With Increased Odds of Limb Loss Among Claudicants Undergoing Infrainguinal Bypass
Vallabhaneni R, Kalbaugh C, Farber M, Tonnessen B, Brothers T, Marston W, Hallett J. Active Smoking Is Associated With Increased Odds of Limb Loss Among Claudicants Undergoing Infrainguinal Bypass. Journal Of Vascular Surgery 2014, 60: 1715. DOI: 10.1016/j.jvs.2014.09.041.Peer-Reviewed Original ResearchActive smokingInfrainguinal bypassDesign and Rationale of Gulf locals with Acute Coronary Syndrome Events (Gulf Coast) Registry
Zubaid M, Thani KB, Rashed W, Alsheikh-Ali A, Alrawahi N, Ridha M, Akbar M, Alenezi F, Alhamdan R, Almahmeed W, Ouda H, Al-Mulla A, Baslaib F, Shehab A, Alnuaimi A, Amin H, Krumholz HM, . Design and Rationale of Gulf locals with Acute Coronary Syndrome Events (Gulf Coast) Registry. The Open Cardiovascular Medicine Journal 2014, 8: 88-93. PMID: 25328551, PMCID: PMC4197526, DOI: 10.2174/1874192401408010088.Peer-Reviewed Original ResearchAcute coronary syndromeST-segment elevation myocardial infarctionElevation myocardial infarctionMyocardial infarctionRisk profileBundle branch block myocardial infarctionDiagnosis of ACSSegment elevation myocardial infarctionCardiovascular risk profileGulf COAST registryHistory of hypertensionOne-year outcomesPast medical historyEvent registryHigh-risk profileActive smokingHospital presentationCoronary syndromePatient demographicsUnstable anginaDischarge diagnosisMean ageTherapeutic managementPhysical findingsMedical history
2013
In Vivo Evidence for β2 Nicotinic Acetylcholine Receptor Subunit Upregulation in Smokers as Compared With Nonsmokers With Schizophrenia
Esterlis I, Ranganathan M, Bois F, Pittman B, Picciotto MR, Shearer L, Anticevic A, Carlson J, Niciu MJ, Cosgrove KP, D’Souza D. In Vivo Evidence for β2 Nicotinic Acetylcholine Receptor Subunit Upregulation in Smokers as Compared With Nonsmokers With Schizophrenia. Biological Psychiatry 2013, 76: 495-502. PMID: 24360979, PMCID: PMC4019710, DOI: 10.1016/j.biopsych.2013.11.001.Peer-Reviewed Original ResearchConceptsLower β2Negative symptomsCortical regionsLower receptor availabilitySelf-medicate symptomsComparison groupLower negative symptomsHigh β2Executive controlExecutive functionNicotine cravingSex-matched comparison subjectsMood assessmentBrain regionsWorse performanceComparison subjectsDiagnosis interactionLimited brain regionsNicotinic acetylcholine receptorsSchizophreniaSingle photon emissionNAChR availabilityActive smokingTobacco smokingPoor outcomeTobacco Smoke Exposure and the Risk of Childhood Acute Lymphoblastic and Myeloid Leukemias by Cytogenetic Subtype
Metayer C, Zhang L, Wiemels JL, Bartley K, Schiffman J, Ma X, Aldrich MC, Chang JS, Selvin S, Fu CH, Ducore J, Smith MT, Buffler PA. Tobacco Smoke Exposure and the Risk of Childhood Acute Lymphoblastic and Myeloid Leukemias by Cytogenetic Subtype. Cancer Epidemiology Biomarkers & Prevention 2013, 22: 1600-1611. PMID: 23853208, PMCID: PMC3769478, DOI: 10.1158/1055-9965.epi-13-0350.Peer-Reviewed Original ResearchConceptsChildren's passive smokingPassive smokingAcute lymphoblastic leukemiaTobacco smokeMyeloid leukemiaCytogenetic subtypesChildhood acute lymphoblastic leukemiaCHILDHOOD ACUTE LYMPHOBLASTICPaternal prenatal smokingPostnatal passive smokingTobacco smoke exposureRisk of childhoodMultivariable regression analysisTiming of exposureB cell precursorsHyperdiploid B cellsActive smokingPrenatal smokingTobacco smokingSmoke exposureLymphoblastic leukemiaAcute lymphoblasticAML casesElevated riskSmoking
2012
Retinoic Acid–related Orphan Receptor-α Is Induced in the Setting of DNA Damage and Promotes Pulmonary Emphysema
Shi Y, Cao J, Gao J, Zheng L, Goodwin A, An CH, Patel A, Lee JS, Duncan SR, Kaminski N, Pandit KV, Rosas IO, Choi AM, Morse D. Retinoic Acid–related Orphan Receptor-α Is Induced in the Setting of DNA Damage and Promotes Pulmonary Emphysema. American Journal Of Respiratory And Critical Care Medicine 2012, 186: 412-419. PMID: 22744720, PMCID: PMC5450975, DOI: 10.1164/rccm.201111-2023oc.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersCells, CulturedDisease Models, AnimalDNA DamageDNA RepairGene Expression ProfilingHumansLungMiceMice, Inbred C57BLMice, Neurologic MutantsNuclear Receptor Subfamily 1, Group F, Member 1Oligonucleotide Array Sequence AnalysisPulmonary Disease, Chronic ObstructivePulmonary EmphysemaTobacco Smoke PollutionConceptsRetinoic acid-related orphan receptorAcid-related orphan receptorCigarette smoke extractLungs of patientsPathogenesis of emphysemaRORA expressionCigarette smokeAirspace enlargementSmoke extractCigarette smoke exposureSmoke-induced emphysemaOrphan receptorDNA damageActive smokingLung transplantationSmoke exposureLung cancerPulmonary emphysemaLung tissueEmphysemaPatientsGene expression profilingApoptotic cell deathMiceEnhanced susceptibility
2010
Complication Rates of Lipoabdominoplasty versus Traditional Abdominoplasty in High-Risk Patients
Samra S, Sawh-Martinez R, Barry O, Persing JA. Complication Rates of Lipoabdominoplasty versus Traditional Abdominoplasty in High-Risk Patients. Plastic & Reconstructive Surgery 2010, 125: 683-690. PMID: 20124853, DOI: 10.1097/prs.0b013e3181c82fb0.Peer-Reviewed Original ResearchConceptsHigh-risk patientsPerfusion-related complicationsComplication rateTraditional abdominoplastyPercent of patientsPrevious abdominal surgeryAbdominal scarringActive smokingChart reviewSmoking historyAbdominal surgeryActive smokersSkin necrosisSurgical revisionWound infectionAbdominal scarRevision surgeryAbdominoplasty flapCosmetic clinicsPatientsComplicationsAbdominoplastyLipoabdominoplastySignificant differencesSurgery
2009
Cardiovascular risk factors and acute-phase response in idiopathic ascending aortitis: a case control study
Chowdhary VR, Crowson CS, Liang KP, Michet CJ, Miller DV, Warrington KJ, Matteson EL. Cardiovascular risk factors and acute-phase response in idiopathic ascending aortitis: a case control study. Arthritis Research & Therapy 2009, 11: r29. PMID: 19250534, PMCID: PMC2688264, DOI: 10.1186/ar2633.Peer-Reviewed Original ResearchConceptsErythrocyte sedimentation rateCase-control studyRisk factorsIdiopathic aortitisAortic aneurysmControl studyElevated acute phase reactantsC-reactive protein levelsCardiovascular risk factorsResultsThe mean ageAscending Aortic AneurysmAcute phase reactantsAcute phase responseActive smokingAscending aortitisInflammatory markersLymphoplasmacytic inflammationSystemic inflammationDiabetes mellitusMean ageControl subjectsRare conditionThoracic aortaFamily historyFemale gender
1996
Asthma among Puerto Rican Hispanics: a multi-ethnic comparison study of risk factors.
Beckett W, Belanger K, Gent J, Holford T, Leaderer B. Asthma among Puerto Rican Hispanics: a multi-ethnic comparison study of risk factors. American Journal Of Respiratory And Critical Care Medicine 1996, 154: 894-899. PMID: 8887582, DOI: 10.1164/ajrccm.154.4.8887582.Peer-Reviewed Original ResearchConceptsRisk factorsPuerto Rican HispanicsSocioeconomic statusHispanic ethnicityHispanic mothersEnvironmental tobacco smoke exposureIndependent risk factorPhysician-diagnosed asthmaPrevalence of asthmaTobacco smoke exposureStrong risk factorAfrican American ethnicityEnvironmental risk factorsYr of ageLow socioeconomic statusStudy of asthmaNon-Hispanic whitesMo of ageActive smokingAsthmatic childrenSmoke exposureChildhood asthmaCigarette smokersMaternal ageMaternal history
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