2022
Serum bicarbonate levels and gait abnormalities in older adults: a cross-sectional study
Ho J, Verghese J, Abramowitz M. Serum bicarbonate levels and gait abnormalities in older adults: a cross-sectional study. Scientific Reports 2022, 12: 9171. PMID: 35654910, PMCID: PMC9163170, DOI: 10.1038/s41598-022-12907-w.Peer-Reviewed Original ResearchConceptsAssociated with worse performanceOlder adultsGait abnormalitiesGait variabilityAssociated with gait abnormalitiesAssociated with impaired physical functionQuantitative measures of gaitDouble support timeMeasures of gaitQuantitative gait analysisShorter stride lengthCommunity-dwelling adultsImpaired physical functionSevere gait abnormalitiesChronic kidney diseaseAssociation of serum bicarbonateCross-sectional studyGait analysisStride lengthPhysical functionSupport timeWorse performanceMiddle tertileMultivariable adjustmentGaitThreat and deprivation are associated with distinct aspects of cognition, emotional processing, and psychopathology in children and adolescents
Schäfer J, McLaughlin K, Manfro G, Pan P, Rohde L, Miguel E, Simioni A, Hoffmann M, Salum G. Threat and deprivation are associated with distinct aspects of cognition, emotional processing, and psychopathology in children and adolescents. Developmental Science 2022, 26: e13267. PMID: 35417607, PMCID: PMC10028496, DOI: 10.1111/desc.13267.Peer-Reviewed Original ResearchConceptsChild Behavior ChecklistExecutive functionEmotional processingChildhood adversityBrazilian High-Risk CohortForms of adversityPoor developmental outcomesAttention biasAngry facesCognitive tasksCognitive developmentDevelopmental correlatesBehavior ChecklistChild developmentDevelopmental outcomesLongitudinal associationsGeneral psychopathologyPsychopathologyAdversityLatent constructsDifferential associationsWorse performanceDistinct aspectsCognitionMeaningful influence
2020
When Culture Influences Genes: Positive Age Beliefs Amplify the Cognitive-Aging Benefit of APOE ε2
Levy BR, Slade MD, Pietrzak RH, Ferrucci L. When Culture Influences Genes: Positive Age Beliefs Amplify the Cognitive-Aging Benefit of APOE ε2. The Journals Of Gerontology Series B 2020, 75: e198-e203. PMID: 32835364, PMCID: PMC7489069, DOI: 10.1093/geronb/gbaa126.Peer-Reviewed Original Research
2019
Relationships between childhood maltreatment, impairment in executive functions and disruptive behavior disorders in a community sample of children
Bernardes E, Manitto A, Miguel E, Pan P, Batistuzzo M, Rohde L, Polanczyk G. Relationships between childhood maltreatment, impairment in executive functions and disruptive behavior disorders in a community sample of children. European Child & Adolescent Psychiatry 2019, 29: 969-978. PMID: 31559500, DOI: 10.1007/s00787-019-01408-3.Peer-Reviewed Original ResearchConceptsDisruptive behavior disordersExecutive functionChildhood maltreatmentCognitive flexibilityEF performanceCommunity sampleBehavior disorderSchool-based sampleCognitive mechanismsCognitive tasksInhibitory controlDisruptive behaviorChild maltreatmentMaltreatmentWorse performanceMental disordersModeratorChildrenImpairmentDisordersIndependent relationshipMemoryFuture studiesAssociationTask
2017
Anxiety modulates the relation between attention-deficit/hyperactivity disorder severity and working memory-related brain activity
van der Meer D, Hoekstra P, van Rooij D, Winkler A, van Ewijk H, Heslenfeld D, Oosterlaan J, Faraone S, Franke B, Buitelaar J, Hartman C. Anxiety modulates the relation between attention-deficit/hyperactivity disorder severity and working memory-related brain activity. The World Journal Of Biological Psychiatry 2017, 19: 450-460. PMID: 28635543, PMCID: PMC5581282, DOI: 10.1080/15622975.2017.1287952.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnxietyAnxiety DisordersAttention Deficit Disorder with HyperactivityCerebellumChildCognitive DysfunctionCohort StudiesComorbidityCorpus StriatumFemaleFunctional NeuroimagingHumansMagnetic Resonance ImagingMaleMemory, Short-TermSeverity of Illness IndexThalamusYoung AdultConceptsAttention-deficit/hyperactivity disorderCo-occurring anxietyADHD severityNeural activityMemory taskAttention-deficit/hyperactivity disorder severityMemory-related brain activityPresence of ADHDVisuospatial Working Memory TaskWorking Memory TaskLevel of anxietyVSWM tasksMemory loadHyperactivity disorderTask accuracyPrevious theorisingAnxiety severityBrain activityNeurobiological heterogeneityDisorder severityAnxietyWorse performanceInformation gatingYoung adultsNeural pathwaysCognitive Control in Generalized Anxiety Disorder: Relation of Inhibition Impairments to Worry and Anxiety Severity
Hallion L, Tolin D, Assaf M, Goethe J, Diefenbach G. Cognitive Control in Generalized Anxiety Disorder: Relation of Inhibition Impairments to Worry and Anxiety Severity. Cognitive Therapy And Research 2017, 41: 610-618. DOI: 10.1007/s10608-017-9832-2.Peer-Reviewed Original ResearchGeneralized anxiety disorderAnxiety severityCognitive controlNoGo taskInhibition impairmentAnxiety disordersGo/NoGo performanceGo/NoGo taskTests of inhibitionNeurocognitive interventionsStroop performanceCognitive modelTrait worryGAD statusGAD symptomsGAD diagnosisWorse performanceQualified supportStroopTaskWorryImpairmentTheoretical modelHealthy controlsDisordersStress and Cognitive Flexibility: Cortisol Increases Are Associated with Enhanced Updating but Impaired Switching
Goldfarb EV, Froböse MI, Cools R, Phelps EA. Stress and Cognitive Flexibility: Cortisol Increases Are Associated with Enhanced Updating but Impaired Switching. Journal Of Cognitive Neuroscience 2017, 29: 14-24. PMID: 27576026, DOI: 10.1162/jocn_a_01029.Peer-Reviewed Original ResearchConceptsCognitive flexibilityDifferent task demandsTask demandsParticipants' cortisol responsesAcute stress manipulationCortisol responseDMS taskStress-related increasesStress manipulationMultifaceted constructImpaired switchingEffects of stressPFC functionSubjects designDimensions of flexibilityWorse performanceDorsal striatumAcute stressCortisol increaseRelevant informationTaskMost studiesParticipantsConstructsParadigm
2016
Language at rest: A longitudinal study of intrinsic functional connectivity in preterm children
Rowlands MA, Scheinost D, Lacadie C, Vohr B, Li F, Schneider KC, Constable R, Ment LR. Language at rest: A longitudinal study of intrinsic functional connectivity in preterm children. NeuroImage Clinical 2016, 11: 149-157. PMID: 26937383, PMCID: PMC4753807, DOI: 10.1016/j.nicl.2016.01.016.Peer-Reviewed Original ResearchConceptsLeft occipito-temporal cortexOccipito-temporal cortexVerbal IQPerformance IQLanguage deficitsSignificant connectivity reductionsPreterm childrenIntrinsic functional connectivityFull IQFunctional connectivity networksFunctional connectivityIQAge 8PT childrenConnectivity reductionLong-range connectionsWorse performanceLinear mixed effects modelsLongitudinal studyConnectivity networksAge 16PT subjectsTS childrenCortical connectivityTerm children
2014
Shallow Encoding and Forgetting Are Associated with Dependence in Instrumental Activities of Daily Living Among Older Adults Living with HIV Infection
Fazeli P, Doyle K, Scott J, Iudicello J, Casaletto K, Weber E, Moore D, Morgan E, Grant I, Woods S, Hampton Atkinson J, Ellis R, Allen McCutchan J, Marcotte T, Marquie-Beck J, Sherman M, Ellis R, Allen McCutchan J, Letendre S, Capparelli E, Schrier R, Rosario D, LeBlanc S, Heaton R, Woods S, Cherner M, Moore D, Morgan E, Dawson M, Jernigan T, Fennema-Notestine C, Archibald S, Hesselink J, Annese J, Taylor M, Masliah E, Achim C, Everall I, Richman D, Smith D, Allen McCutchan J, Achim C, Lipton S, Hampton Atkinson J, Gamst A, Cushman C, Abramson I, Vaida F, Deutsch R, Umlauf A. Shallow Encoding and Forgetting Are Associated with Dependence in Instrumental Activities of Daily Living Among Older Adults Living with HIV Infection. Archives Of Clinical Neuropsychology 2014, 29: 278-288. PMID: 24695591, PMCID: PMC4000232, DOI: 10.1093/arclin/acu009.Peer-Reviewed Original ResearchConceptsCalifornia Verbal Learning Test-Second EditionMemory deficitsIADL dependenceReal-world functioningLogical Memory subtestInstrumental activitiesMemory subtestsShallow encodingRecency effectMemory predictorsDaily livingOlder adultsWorse performanceForgettingOlder groupEncodingOlder HIVADL questionnaireHIV infectionRisk factorsDeficitsHIVAdultsSubtestsYounger cohorts
2013
In Vivo Evidence for β2 Nicotinic Acetylcholine Receptor Subunit Upregulation in Smokers as Compared With Nonsmokers With Schizophrenia
Esterlis I, Ranganathan M, Bois F, Pittman B, Picciotto MR, Shearer L, Anticevic A, Carlson J, Niciu MJ, Cosgrove KP, D’Souza D. In Vivo Evidence for β2 Nicotinic Acetylcholine Receptor Subunit Upregulation in Smokers as Compared With Nonsmokers With Schizophrenia. Biological Psychiatry 2013, 76: 495-502. PMID: 24360979, PMCID: PMC4019710, DOI: 10.1016/j.biopsych.2013.11.001.Peer-Reviewed Original ResearchConceptsLower β2Negative symptomsCortical regionsLower receptor availabilitySelf-medicate symptomsComparison groupLower negative symptomsHigh β2Executive controlExecutive functionNicotine cravingSex-matched comparison subjectsMood assessmentBrain regionsWorse performanceComparison subjectsDiagnosis interactionLimited brain regionsNicotinic acetylcholine receptorsSchizophreniaSingle photon emissionNAChR availabilityActive smokingTobacco smokingPoor outcome
2010
Visual memory in patients after anterior right temporal lobectomy and adult normative data for the Brown Location Test
Brown FC, Tuttle E, Westerveld M, Ferraro FR, Chmielowiec T, Vandemore M, Gibson-Beverly G, Bemus L, Roth RM, Blumenfeld H, Spencer DD, Spencer SS. Visual memory in patients after anterior right temporal lobectomy and adult normative data for the Brown Location Test. Epilepsy & Behavior 2010, 17: 215-220. PMID: 20056493, PMCID: PMC2825669, DOI: 10.1016/j.yebeh.2009.11.026.Peer-Reviewed Original ResearchConceptsVisual memoryLocation learningNormative dataLocation testLarge meta-analytic studiesAnterior mesial temporal lobeTemporal lobectomyRight temporal lobectomyAdult normative dataTemporal lobe changesMeta-analytic studyMemory testNormative sampleMemory deficitsMesial temporal lobectomyTemporal lobeStandardized scoresWorse performanceMemoryMesial temporal lobeHealthy adultsPresent findingsLearningLobectomy groupConsistent relationship
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