2025
Causal Mediation Analysis for the Intergenerational Transmission of Violence Reveals Pathways From Child Maltreatment to Elder Mistreatment
Pickering C, Yildiz M, Browning W, Chilatra J, Yefimova M, Maxwell C, Sullivan T. Causal Mediation Analysis for the Intergenerational Transmission of Violence Reveals Pathways From Child Maltreatment to Elder Mistreatment. The Gerontologist 2025, 65: gnaf132. PMID: 40244912, PMCID: PMC12129107, DOI: 10.1093/geront/gnaf132.Peer-Reviewed Original ResearchConceptsChild maltreatment victimsMaltreatment victimsElder mistreatmentIntergenerational transmissionIntergenerational transmission of violenceMediation modelFamily caregiversTransmission of violenceLife course trajectoriesChild maltreatment historyLife course viewTrajectories of familiesSerial mediation modelDementia family caregiversEarly-life experiencesFamily caregiver roleChild maltreatmentEmotion dysregulationEmotional processingAttribution biasMaltreatment historyCausal mediation analysisObservational longitudinal studyCognitive processesMediation analysisImpact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study
Ota V, Oliveira A, Bugiga A, Conceição H, Galante P, Asprino P, Schäfer J, Hoffmann M, Bressan R, Brietzke E, Manfro G, Grassi-Oliveira R, Gadelha A, Rohde L, Miguel E, Pan P, Santoro M, Salum G, Carvalho C, Belangero S. Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study. Frontiers In Psychiatry 2025, 16: 1505421. PMID: 40018685, PMCID: PMC11866055, DOI: 10.3389/fpsyt.2025.1505421.Peer-Reviewed Original ResearchBrazilian High-Risk Cohort StudyChild Behavior ChecklistHigh Risk Cohort StudyLife adversityPsychiatric symptomsExternalizing symptomsDevelopment of psychiatric symptomsAssociated with depressive symptomsEarly life adversityStressful life eventsAssociated with psychiatric phenotypesPsychiatric phenotypesBehavior ChecklistDepressive symptomsLife eventsMental disordersPsychopathologyNo mediationChild maltreatmentCohort studyLatent factorsAssociated with deprivationAdversityModerating effectMental condition
2024
The Circumstances Surrounding Fatal Pediatric Opioid Poisonings, 2004-2020.
Gaither J, McCollum S, Bechtel K, Leventhal J, Mintz S. The Circumstances Surrounding Fatal Pediatric Opioid Poisonings, 2004-2020. 2024, 154 PMID: 39484873, PMCID: PMC11528886, DOI: 10.1542/peds.2024-067043n.Peer-Reviewed Original ResearchConceptsChild's own homeOpioid poisoningOwn homeHistory of maltreatmentSubstance use/abuseAge groupsDied of homicidePrimary caregiversYears of ageOpioid prescribingChildren 0Opioid fatalitiesHousehold factorsPrescription opioidsSubstance useChild maltreatmentCaregiversDecedentsReporting systemIllicit fentanylMaltreatmentChildrenFatal opioid poisoningsAgeHomeTelehealth in Home Visiting for New Mothers: Are Outcomes Different if the First Visits Are in Person?
Holland M, Fitch D, Regmi D, Sadler L. Telehealth in Home Visiting for New Mothers: Are Outcomes Different if the First Visits Are in Person? Prevention Science 2024, 25: 1153-1163. PMID: 39349915, PMCID: PMC11519217, DOI: 10.1007/s11121-024-01731-5.Peer-Reviewed Original ResearchIntimate partner violenceHome visitsChild developmentLikelihood of elevated depressive symptomsNurse-Family PartnershipHome visiting programsElevated depressive symptomsIn-Person VisitsEvidence-based modelPartner violenceSecondary data analysisChild maltreatmentLikelihood of breastfeedingAged 6 monthsLikelihood of retentionVisiting programsChild healthNew mothersChildren Aged 6 MonthsDepressive symptomsVideo encountersIn-personNatural experimentScreening assessmentProgram involvementProspective and Retrospective Measures of Child Maltreatment and Their Association With Psychopathology
Baldwin J, Coleman O, Francis E, Danese A. Prospective and Retrospective Measures of Child Maltreatment and Their Association With Psychopathology. JAMA Psychiatry 2024, 81: 769-781. PMID: 38691376, PMCID: PMC11063927, DOI: 10.1001/jamapsychiatry.2024.0818.Peer-Reviewed Original ResearchMeasures of child maltreatmentChildhood maltreatmentMultilevel random effects meta-analysesRetrospective measuresChild maltreatmentMeta-analysesRandom-effects meta-analysesProspective measuresPredictors of heterogeneityPeer-reviewed studiesAssessment of psychopathologyStatistically significant moderatorMain OutcomesUnadjusted analysisSelf-ReportPreregistered protocolData extractionCognitive interventionsDistressing memoriesEmotional disordersPsychopathologyObservational studyChildhood eventsSignificant moderatorThird-person accountsChild Maltreatment, Adult Trauma, and Mental Health Symptoms Among Women Veterans: A Scoping Review of Published Quantitative Research
Presseau C, Carney J, Kline N, Grimshaw A, DeMoss L, Gunderson C, Portnoy G. Child Maltreatment, Adult Trauma, and Mental Health Symptoms Among Women Veterans: A Scoping Review of Published Quantitative Research. Trauma Violence & Abuse 2024, 25: 3020-3036. PMID: 38468375, DOI: 10.1177/15248380241234345.Peer-Reviewed Original ResearchAdult trauma exposureMental health symptomsTrauma exposureWomen veteransChild maltreatmentHealth symptomsAdult traumaScoping ReviewMental healthExposure to child maltreatmentPosttraumatic stress symptomatologySample of women veteransLifetime trauma exposureInfluence of child maltreatmentVeterans' mental healthU.S. women veteransStress symptomatologySelf-reported survey dataPeer-reviewed journalsConvenience sampleMaltreatmentUnique articlesDatabase inceptionPublished quantitative researchRepresentative sampleJuvenile Offending Among Maltreated Youth: Assessing Type-Specificity and Offense Specialization in the Cycle of Violence
Kurpiel A, Connell C, Font S. Juvenile Offending Among Maltreated Youth: Assessing Type-Specificity and Offense Specialization in the Cycle of Violence. Crime & Delinquency 2024 DOI: 10.1177/00111287231225143.Peer-Reviewed Original ResearchCycle of violenceJuvenile offendersPhysical abuseYouth exposed to child maltreatmentOffense specializationOffending recordsSex offendersParental incarcerationAbuse victimsSexual abuseOffendersChild maltreatmentMaltreated youthAbuseTreatment servicesOffensesViolenceYouthMoral neglectParenting behaviorsMaltreatmentNeglectIncarcerationVictimsIllicitEffects of child trauma screening on trauma‐informed multidisciplinary evaluation and service planning in the child welfare system
Connell C, Swanson A, Genovese M, Lang J. Effects of child trauma screening on trauma‐informed multidisciplinary evaluation and service planning in the child welfare system. Journal Of Traumatic Stress 2024, 37: 337-343. PMID: 38193592, DOI: 10.1002/jts.23001.Peer-Reviewed Original ResearchRecord reviewMultidisciplinary evaluationTrauma screeningLong-term sequelaeRetrospective record reviewPrevalence of exposureEvidence-based interventionsTrauma-focused servicesTrauma-related symptomsProvider recommendationEarly identificationPTE exposureService planningChild welfare systemRandom sampleScreening procedureFormal screening procedureTraumatic eventsChild maltreatmentSignificant improvementChildrenExposureScreeningScreening processLt
2023
The association of epigenetic age acceleration and depressive and anxiety symptom severity among children recently exposed to substantiated maltreatment
Zhang Z, Moeckel C, Mustafa M, Pham H, Olson A, Mehta D, Dorn L, Engeland C, Shenk C. The association of epigenetic age acceleration and depressive and anxiety symptom severity among children recently exposed to substantiated maltreatment. Journal Of Psychiatric Research 2023, 165: 7-13. PMID: 37441927, PMCID: PMC10529086, DOI: 10.1016/j.jpsychires.2023.07.007.Peer-Reviewed Original ResearchConceptsEpigenetic age accelerationSymptom severityAnxiety symptom severitySevere depressiveGreater riskAnxiety disordersStress-sensitive biomarkersAnxiety symptomsMajor risk factorAge accelerationYears of ageMultiple psychiatric disordersChild maltreatmentHorvath clockPediatric populationRisk factorsSubstantiated child maltreatmentPsychiatric disordersPromising biomarkerPredictive valueDiagnostic thresholdDepressiveChildren 8Transitory symptomsSymptomsInvestigating the effects of maltreatment and acute stress on the concordance of blood and DNA methylation methods of estimating immune cell proportions
Apsley A, Etzel L, Hastings W, Heim C, Noll J, O’Donnell K, Schreier H, Shenk C, Ye Q, Shalev I. Investigating the effects of maltreatment and acute stress on the concordance of blood and DNA methylation methods of estimating immune cell proportions. Clinical Epigenetics 2023, 15: 33. PMID: 36855187, PMCID: PMC9976543, DOI: 10.1186/s13148-023-01437-5.Peer-Reviewed Original ResearchConceptsComplete blood countImmune cell proportionsAcute psychosocial stressCell proportionPsychosocial stressPsychosocial stress altersImmune cell subtypesAcute laboratory stressorEarly life adversityStress-exposed individualsChild maltreatmentPediatric cohortBlood countCell subtypesAcute stressStress-induced changesPathophysiological statesLife adversityCritical covariatesLaboratory stressorYoung adultsEffects of maltreatmentDNAm alterationsClinical populationsDNA methylation
2022
Integrating responses to caregiver substance misuse, intimate partner violence and child maltreatment: Initiatives and policies that support families at risk for entering the child welfare system
Bosk E, Van Scoyoc A, Mihalec-Adkins B, Conrad A, Hanson K, Chaiyachati B. Integrating responses to caregiver substance misuse, intimate partner violence and child maltreatment: Initiatives and policies that support families at risk for entering the child welfare system. Aggression And Violent Behavior 2022, 65: 101637. DOI: 10.1016/j.avb.2021.101637.Peer-Reviewed Original ResearchIntimate partner violencePartner violenceChild maltreatmentConceptual paperChild welfare systemWelfare systemTransformative servicesPolicy optionsPrevention ActViolenceInnovative programsUnited StatesPractical discussionMaltreatmentSubstance misuseComplex traumaFundamental elementsPositive trajectoryInnovative approachCommon elementsTheoretical foundationPolicyIntegrative approachFamilyInitiativesInattention symptoms in early pregnancy predict parenting skills and infant maltreatment during the first year of life
de Oliveira J, Fatori D, Shephard E, Xavier M, Matijasevich A, Ferraro A, Rohde L, Chiesa A, Miguel E, Polanczyk G. Inattention symptoms in early pregnancy predict parenting skills and infant maltreatment during the first year of life. Brazilian Journal Of Psychiatry 2022, 44: 388-400. PMID: 35751597, PMCID: PMC9375657, DOI: 10.47626/1516-4446-2021-2045.Peer-Reviewed Original ResearchConceptsMaternal attention-deficit/hyperactivity disorderAttention-deficit/hyperactivity disorderHyperactivity/impulsivity symptomsInattention symptomsImpulsivity symptomsAdolescent mothersHyperactivity disorderMaternal inattentionInfant maltreatmentEarly intervention programsParenting skillsPoor home environmentInfant developmentIntervention programsInattentionChild maltreatmentMaternal competenceMaltreatmentSkillsHome visit programHome environmentFirst yearInfant's lifeMultilevel linear regression modelsEarly pregnancy
2021
Trust and childhood maltreatment: evidence of bias in appraisal of unfamiliar faces
Neil L, Viding E, Armbruster‐Genc D, Lisi M, Mareschal I, Rankin G, Sharp M, Phillips H, Rapley J, Martin P, McCrory E. Trust and childhood maltreatment: evidence of bias in appraisal of unfamiliar faces. Journal Of Child Psychology And Psychiatry 2021, 63: 655-662. PMID: 34500497, DOI: 10.1111/jcpp.13503.Peer-Reviewed Original ResearchConceptsTrust processingUnfamiliar facesChildhood maltreatmentPoor social functioningMental health difficultiesMental health problemsFacial stimuliCognitive abilitiesTrust judgmentsTrust attributionTrustworthiness dimensionsCommunity-based sampleSocial service recordsSocial functioningMaltreatment experiencesHealth difficultiesChild maltreatmentMaltreatmentSocial bondsAtypical patternsPeersEvidence of biasChildrenSocioeconomic statusProcessingChild Maltreatment, Peer Victimization, and Mental Health: Neurocognitive Perspectives on the Cycle of Victimization
Goemans A, Viding E, McCrory E. Child Maltreatment, Peer Victimization, and Mental Health: Neurocognitive Perspectives on the Cycle of Victimization. Trauma Violence & Abuse 2021, 24: 530-548. PMID: 34355601, PMCID: PMC10009486, DOI: 10.1177/15248380211036393.Peer-Reviewed Original ResearchConceptsMental healthMental health careMental health outcomesAdverse childhood experiencesMental health vulnerabilitiesSystematic scoping reviewInpatient populationChild maltreatmentHealth outcomesGoogle ScholarHealth careNeurocognitive functioningPutative mechanismsRisk of revictimizationScoping ReviewHealth vulnerabilityChildrenNeurocognitive findingsPreventative modelAdditive effectChildhood experiencesRiskPeer victimizationHealthMaltreatment
2019
A review of childhood maltreatment, latent vulnerability and the brain: implications for clinical practice and prevention
Gerin M, Hanson E, Viding E, McCrory E. A review of childhood maltreatment, latent vulnerability and the brain: implications for clinical practice and prevention. Adoption & Fostering 2019, 43: 310-328. DOI: 10.1177/0308575919865356.Peer-Reviewed Original ResearchMental health problemsLatent vulnerabilityNeurocognitive alterationsChildhood maltreatmentFuture mental health problemsEarly adverse environmentsCommon mental health problemsEmotion regulationThreat processingExecutive controlNeurocognitive systemsHealth problemsPoor mental healthReward processingMaltreated childrenFunctional neuroimagingFuture psychopathologyChild maltreatmentMental healthMaltreatmentLong-term outcomesSuch experiencesFunctioningClinical implicationsChildrenRelationships between childhood maltreatment, impairment in executive functions and disruptive behavior disorders in a community sample of children
Bernardes E, Manitto A, Miguel E, Pan P, Batistuzzo M, Rohde L, Polanczyk G. Relationships between childhood maltreatment, impairment in executive functions and disruptive behavior disorders in a community sample of children. European Child & Adolescent Psychiatry 2019, 29: 969-978. PMID: 31559500, DOI: 10.1007/s00787-019-01408-3.Peer-Reviewed Original ResearchConceptsDisruptive behavior disordersExecutive functionChildhood maltreatmentCognitive flexibilityEF performanceCommunity sampleBehavior disorderSchool-based sampleCognitive mechanismsCognitive tasksInhibitory controlDisruptive behaviorChild maltreatmentMaltreatmentWorse performanceMental disordersModeratorChildrenImpairmentDisordersIndependent relationshipMemoryFuture studiesAssociationTaskA randomized pilot trial of two parenting interventions for fathers in residential substance use disorder treatment
Stover CS, McMahon TJ, Moore K. A randomized pilot trial of two parenting interventions for fathers in residential substance use disorder treatment. Journal Of Substance Use And Addiction Treatment 2019, 104: 116-127. PMID: 31370975, PMCID: PMC6699774, DOI: 10.1016/j.jsat.2019.07.003.Peer-Reviewed Original ResearchConceptsSubstance misuse treatment programsIntimate partner violenceTreatment programRandomized pilot trialPilot trialBooster sessionsSubstance use relapseChild maltreatmentPsychoeducational interventionResidential substanceDisorder treatmentSubstance misuseDysregulation symptomsFocused interventionsGreater decreaseInterventionDysregulation problemsIndividual treatmentResidential treatmentAftercare sessionsSignificant differencesTreatmentSignificant reductionResidential facilitiesTrialsUnderstanding risk and resilience in maltreated children
Kaufman J, Montalvo-Ortiz J, Lee R. Understanding risk and resilience in maltreated children. 2019, 304-323. DOI: 10.1093/oso/9780198793014.003.0021.ChaptersHistory of abuseMaltreated youthRelevant empirical workFunctional brain changesPsychiatric disordersMeta-analytic studyMultiple brain regionsCognitive processesSubstance use disordersMaltreated childrenBrain measuresGenetic factorsPoor treatment responseDistinct psychiatric disordersResiliency StudyNeural plasticityBrain regionsChild abuseChild maltreatmentBrain changesEnrichment experiencesDiverse clinical phenotypesUse disordersPositive supportClinical interventionsEffects of the interaction between genetic factors and maltreatment on child and adolescent psychiatric disorders
Carvalho C, Pan P, Ota V, Spindola L, Xavier G, Santoro M, Mazzotti D, Pellegrino R, Hakonarson H, Rohde L, Miguel E, Gadelha A, Bressan R, Belangero S. Effects of the interaction between genetic factors and maltreatment on child and adolescent psychiatric disorders. Psychiatry Research 2019, 273: 575-577. PMID: 30716596, DOI: 10.1016/j.psychres.2019.01.078.Peer-Reviewed Original ResearchConceptsMental disordersSingle nucleotide polymorphismsSchool-based prospective studyAdolescent psychiatric disordersBonferroni multiple comparison correctionChild maltreatmentProspective studyPsychiatric disordersMultiple comparison correctionSignificant associationGenetic factorsDisordersNucleotide polymorphismsPsychopathologyLogistic modelMaltreatment
2018
Lighthouse Parenting Programme: Description and pilot evaluation of mentalization-based treatment to address child maltreatment
Byrne G, Sleed M, Midgley N, Fearon P, Mein C, Bateman A, Fonagy P. Lighthouse Parenting Programme: Description and pilot evaluation of mentalization-based treatment to address child maltreatment. Clinical Child Psychology And Psychiatry 2018, 24: 680-693. PMID: 30387373, DOI: 10.1177/1359104518807741.Peer-Reviewed Original ResearchConceptsMentalization-based treatmentChild maltreatmentInner worldChild's inner worldPilot evaluationParenting ProgramAntisocial personality disorderSensitive caregivingParents' capacityChild developmentRisk of maltreatmentMaltreatmentPersonality disorderParentsChildrenHarmful responsesCaregivingRelationshipMisunderstandingTreatmentProgramCuriosityDisordersInterventionAttachment
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