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Jaime Grutzendler, MD

Dr. Harry M. Zimmerman and Dr. Nicholas and Viola Spinelli Professor of Neurology and Neuroscience; Vice-Chair for Research, Neurology; Director, Center for Experimental Neuroimaging

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Jaime Grutzendler, MD

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Dr. Grutzendler obtained his MD from Universidad Javeriana in Bogota, Colombia, where he was born and raised. He completed a medical internship in Internal Medicine and a residency in Neurology at Washington University/Barnes-Jewish Hospital in St. Louis. Following that, he pursued a combined clinical and research fellowship in the Alzheimer Disease Research Center and the Department of Neurobiology at Washington University, with additional neurobiology research training at the Skirball Institute of New York University. Dr. Grutzendler's laboratory is dedicated to understanding the cellular and molecular mechanisms of normal brain function and neuropathology. They have a particular focus on elucidating mechanisms underlying neurodegeneration, such as those found in Alzheimer's disease. Additionally, they aim to advance the understanding of cell-cell interactions through the utilization of intravital optical imaging techniques, enabling them to study the brain in real-time and observe dynamic processes at the cellular and molecular levels. Moreover, their laboratory is interested in developing therapeutics for brain disorders. Leveraging their expertise in brain imaging, they work with chemists to develop novel small molecules to target specific brain cell types for drug delivery and as imaging probes. In addition to the research endeavors, Dr. Grutzendler is actively involved in clinical activities focused on dementia and Alzheimer's patients. He works closely with individuals affected by these neurodegenerative disorders, providing comprehensive care and support.

Education & Training

  • Postdoctoral Fellow
    Skirball Institute/New York University (2003)
  • Research Fellow
    Washington University in St. Louis (2000)
  • Clinical Fellow
    Washington University in St. Louis (2000)
  • Resident
    Washington Univeristy in St. Louis (1998)
  • Intern
    Washington University in St. Louis (1995)
  • MD
    Universidad Javeriana School of Medicine (1991)

Honors & Recognition

AwardAwarding OrganizationDate
Connecticut Academy of Science and Engineering, Elected Member2018
Connecticut Academy of Science and Engineering, Elected Member2017
American Society for Clinical Investigation, Elected Member2012
McCance Yale Scholar2011
NIH Director’s Transformative Research Award2010
Brain and Immunoimaging AwardDana Foundation2004
New Scholar AwardEllison Foundation2004

Departments & Organizations