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Poststroke seizures increase risk for mortality and poor outcomes
medwireNews: Patients with a history of stroke have a significantly increased risk for mortality, poor functional outcomes, and severe disability if they have poststroke seizures (PSS), a systematic review and meta-analysis shows.
“The findings highlight that PSSs are a public health concern and warrant significant research efforts to prevent poststroke epileptogenesis,” say the researchers in JAMA Neurology.
Nishant Mishra (Yale University, New Haven, Connecticut, USA) and colleagues analyzed 71 observational, mainly retrospective (66%), studies that were carried out between 1951 and 2023 to compare outcomes for 20,110 stroke patients with PSS and 1,166,085 without PSS. Follow-up ranged from hospital discharge to 26 years.
“We suggest that within-study comparisons should be valid if follow- up was the same for patients with and without PSS, but absolute values are not readily interpretable,” say the researchers.
Source: Springer Medicine