Shannon Lynch, APRN, FNP (BC)
Staff Affiliate - YNHHCards
About
Research
Publications
2026
Assessing the impact of cardiovascular disease and ADT on survival disparities in prostate cancer.
Ragin C, Ruth K, He Z, Horwitz E, Edmundowicz D, Devarajan K, Lynch S, Turner D, Harrison S, Gibbs D, Turner P, Plimack E, Chen D, Uzzo R, Kutikov A, Zibelman M, Geynisman D. Assessing the impact of cardiovascular disease and ADT on survival disparities in prostate cancer. Journal Of Clinical Oncology 2026, 44: 268-268. DOI: 10.1200/jco.2026.44.7_suppl.268.Peer-Reviewed Original ResearchAndrogen deprivation therapy useAndrogen deprivation therapyProstate cancerOverall survivalCardiovascular diseaseRadiation therapyAssociated with androgen deprivation therapyFollow-upAndrogen deprivation therapy effectivenessInstitutional prostate cancer databaseAndrogen deprivation therapy groupStage IIIEarly-stage prostate cancerEarly stage PCaAndrogen deprivation therapy patientsNo-ADT groupAggressive prostate cancerMedian Follow-UpProstate cancer databaseStage prostate cancerProstate cancer patientsPre-existing cardiovascular diseaseLog-rank testCox proportional hazards modelsAssociated with mortalityInvestigating disparities in hepatocellular carcinoma and their effect on patterns of systemic care: An updated analysis.
Ioffe D, Lynch S, Handorf E, Zhang L, Dotan E. Investigating disparities in hepatocellular carcinoma and their effect on patterns of systemic care: An updated analysis. Journal Of Clinical Oncology 2026, 44: 489-489. DOI: 10.1200/jco.2026.44.2_suppl.489.Peer-Reviewed Original ResearchSocioeconomic status indexLow socioeconomic statusSocioeconomic statusSES indexLow SES indexHepatocellular carcinomaHealth Research DatabaseMetastatic HCCImpact of disparitiesHepatocellular carcinoma burdenCare deliveryCumulative incidenceHepatocellular carcinoma risk factorsChi-square testSystem careHispanic patientsRate of treatmentResearch DatabaseSecond-line therapyMetastatic hepatocellular carcinomaNumerically higher rateDisadvantaged groupsRisk factorsDisparitiesUS-basedAge-based outcomes and patterns of care of patients with metastatic pancreatic cancer: An updated comparative analysis from Fox Chase Cancer Center.
Adavelly P, Pillarisetti P, Dotan E, Renning A, Zhang L, Sridharan A, Vijayvergia N, Lynch S, Ioffe D. Age-based outcomes and patterns of care of patients with metastatic pancreatic cancer: An updated comparative analysis from Fox Chase Cancer Center. Journal Of Clinical Oncology 2026, 44: 668-668. DOI: 10.1200/jco.2026.44.2_suppl.668.Peer-Reviewed Original ResearchMetastatic pancreatic cancerFox Chase Cancer CenterOverall survivalTreatment patternsPancreatic cancerFirst-line triplet chemotherapyAssociated with inferior OSCancer CenterMultivariate Cox proportional hazards modelPatterns of care of patientsFirst-line FOLFIRINOXPredictors of OSSecond-line chemotherapyMulti-agent chemotherapySecond-line therapySingle-agent chemotherapyAnalysis of patientsLog-rank testKaplan-Meier curvesCox proportional hazards modelsAge-based differencesOlder adults >Standard of careYoung adults <Proportional hazards model
2025
Associations Between Neighborhood Environment, Childhood Adversity, and Cancer Risk: A Geospatial Analysis
DuBois T, Lynch S, Banks J, Sarwer D, Schroeder K. Associations Between Neighborhood Environment, Childhood Adversity, and Cancer Risk: A Geospatial Analysis. Cancer Medicine 2025, 14: e71331. PMID: 41163396, PMCID: PMC12572626, DOI: 10.1002/cam4.71331.Peer-Reviewed Original ResearchConceptsNeighborhood-level measuresCancer prevention guidelinesCancer prevention behaviorsCancer mortalityPrevention guidelinesRisk factorsPreventive behaviorsNeighborhood-level risk factorsHighest cancer mortality ratesCancer prevention effortsCancer registry dataCancer mortality ratesHigher cancer mortalityNeighborhood risk factorsMultivariate linear regression analysisNeighborhood environmentCancer riskSocio-ecological perspectiveRegistry dataPrevention effortsLevels of traumaLinear regression analysisChildhood adversityNeighborhood levelMeasures of traumaBeyond smoking: A geospatial investigation of factors associated with lung and bronchus cancer risk in Pennsylvania
DuBois T, Wiese D, Henry K, Lynch S. Beyond smoking: A geospatial investigation of factors associated with lung and bronchus cancer risk in Pennsylvania. Social Science & Medicine 2025, 384: 118485. PMID: 40944988, DOI: 10.1016/j.socscimed.2025.118485.Peer-Reviewed Original ResearchSmoking ratesGeospatial investigationRisk factorsArea-level risk factorsHigher rates of smokingCancer registry dataRates of smokingTargeted prevention strategiesElevated incidence ratesCensus tract levelBronchus cancerSpatial scan statisticAssociated risk factorsCancer riskHigher RatesRegistry dataElevated ratesHigh-incidence areasTract levelIncidence ratePrevention strategiesNever-smokersGeographical areasSocioeconomic riskSmokingInvestigation of Treatment‐Related Disparities in Metastatic Pancreatic Cancer Patients Using Real‐World Data
Aluri L, Brown C, Sridharan A, Handorf E, Sorice K, Dotan E, Lynch S. Investigation of Treatment‐Related Disparities in Metastatic Pancreatic Cancer Patients Using Real‐World Data. Cancer Medicine 2025, 14: e71108. PMID: 40772475, PMCID: PMC12329563, DOI: 10.1002/cam4.71108.Peer-Reviewed Original ResearchConceptsMetastatic pancreatic adenocarcinomaFirst-line therapyOverall survivalElectronic health recordsDiagnosis of metastatic pancreatic adenocarcinomaMedian numberWhite patientsNational Comprehensive Cancer Network guidelinesMetastatic pancreatic cancer patientsCox proportional hazards regression modelsDiverse cohort of patientsSurvival of patientsSystemic anticancer therapyEarly-stage diseaseLog-rank testCohort of patientsKaplan-Meier curvesOverall treatmentProportional hazards regression modelsPancreatic cancer patientsOverall treatment of patientsTreatment of patientsDiverse cohortTreatment-related disparitiesHazards regression modelsLeveraging geospatial data to support an implementation science approach to address lung cancer burden
DuBois T, Brecher A, Edmondson D, Gonzalez E, Zeigler-Johnson C, Fleisher L, Lynch S. Leveraging geospatial data to support an implementation science approach to address lung cancer burden. JNCI Cancer Spectrum 2025, 9: pkaf047. PMID: 40341560, PMCID: PMC12132098, DOI: 10.1093/jncics/pkaf047.Peer-Reviewed Original ResearchConceptsTobacco treatment programImplementation science approachPrevention effortsLung cancer mortality ratesCancer mortality ratesLung cancer burdenMaintenance frameworkTreatment programsCancer burdenSupport deliverySmoking cessationNational ratesContextual factorsInterventionMortality rateBrief reportPreventionProgramScience approachSmokingTobaccoBurdenImplementationCessationPartnershipDoes inclusion of neighborhood variables improve clinical risk prediction for advanced prostate cancer in Black and White men?
Tagai E, Handorf E, Sorice K, Fang C, Deng M, Daly M, Reese A, Henry K, Ragin C, Lynch S. Does inclusion of neighborhood variables improve clinical risk prediction for advanced prostate cancer in Black and White men? Urologic Oncology Seminars And Original Investigations 2025, 43: 334.e17-334.e24. PMID: 40121103, PMCID: PMC12068980, DOI: 10.1016/j.urolonc.2025.02.021.Peer-Reviewed Original ResearchConceptsNeighborhood-level variablesProstate Cancer Prevention TrialNeighborhood variablesProtective service occupationsBlack menNeighborhood-level risk factorsWhite menNeighborhood-level povertyMedical oncology clinicUniversity Health SystemCancer Prevention TrialRisk prediction toolsLogistic regression modelsRisk prediction modelSocial environmental variablesPatients' medical recordsService occupationsHigh-grade PCaCurrent risk prediction modelsHealth systemPersistent disparitiesOncology clinicInsurance statusAssociated with ratesClinical risk predictionPalliative Care and End-of-Life Care in Metastatic Pancreatic Cancer
O’Brien J, Halsey B, Connors M, Deng M, Handorf E, Berardi G, Lynch S, Sorice K, Reddy S, Meyer J, Bauman J, Dotan E. Palliative Care and End-of-Life Care in Metastatic Pancreatic Cancer. Journal Of Palliative Medicine 2025, 28: 217-223. PMID: 39636708, DOI: 10.1089/jpm.2024.0313.Peer-Reviewed Original ResearchEnd of lifeAggressive EOL carePalliative careDay of deathEOL carePC consultationIntegration of palliative careEnd of life careEnd-of-life careAssociated with worse qualityHealth care resourcesMetastatic pancreatic cancerQuality of lifePC teamAggressive careCare resourcesHospiceAverage length of timeTertiary cancer centerCareWorse qualityAverage timeCancer CenterBenefit patientsPancreatic cancerRacial/Ethnic Differences and Effects of Clinical/Socioeconomic Factors on Time from Diagnosis to Treatment in Pancreatic Cancer
Sridharan A, Dotan E, Dorta M, Vemula N, Handorf E, Deng M, Renning A, Sorice K, Laderman L, Whittington K, Cukierman E, Astsaturov I, Vijayvergia N, Meyer J, Reddy S, Lynch S. Racial/Ethnic Differences and Effects of Clinical/Socioeconomic Factors on Time from Diagnosis to Treatment in Pancreatic Cancer. Journal Of Gastrointestinal Cancer 2025, 56: 67. PMID: 39954184, PMCID: PMC11829832, DOI: 10.1007/s12029-025-01188-x.Peer-Reviewed Original ResearchConceptsSocioeconomic statusHazard ratioConfidence intervalsSocioeconomic status populationsCancer CenterComprehensive cancer centerDiagnosis to first treatmentPatient-level variablesAcademic cancer centerCox proportional hazards regressionReceipt of chemotherapyMultivariable Cox proportional hazards regressionProportional hazards regressionT2TCancer disparitiesNeighborhood deprivationRace/ethnic disparitiesDisparity indicatorsRacial/Ethnic DifferencesHospital settingEffects of racePatient raceDiagnosis to treatmentUS CensusMetastatic PDAC
Clinical Care
Overview
Shannon Lynch is an interventional cardiology specialist who focuses on diagnosing and treating conditions related to the heart and blood vessels. She offers a variety of procedures aimed at improving heart health and managing cardiovascular diseases, addressing issues such as blocked arteries and heart rhythm disorders.
Lynch earned her nursing as family nurse practitioner degree at Sacred Heart University. She is affiliated with YNHH, and though she holds a specialty as a family nurse practitioner, this biography highlights her focus on interventional cardiology.
Clinical Specialties
Interventional Cardiology
Board Certifications
Family Nurse Practitioner
- Certification Organization
- American Academy of Nurse Practitioner's Certification Program
- Original Certification Date
- 2017