2000
Prospective cohort study of children born to human immunodeficiency virus-infected mothers, 1985 through 1997: trends in the risk of vertical transmission, mortality and acquired immunodeficiency syndrome indicator diseases in the era before highly active antiretroviral therapy
SIMPSON J, SHAPIRO E, ANDIMAN W. Prospective cohort study of children born to human immunodeficiency virus-infected mothers, 1985 through 1997: trends in the risk of vertical transmission, mortality and acquired immunodeficiency syndrome indicator diseases in the era before highly active antiretroviral therapy. The Pediatric Infectious Disease Journal 2000, 19: 618-624. PMID: 10917219, DOI: 10.1097/00006454-200007000-00007.Peer-Reviewed Original ResearchConceptsAIDS indicator diseasesMonths of ageIndicator diseasesInfected childrenVertical transmissionCohort studyHuman immunodeficiency virus-infected mothersMycobacterium avium complex diseaseActive antiretroviral therapyHIV infection statusPerson monthsProspective cohort studyPneumocystis carinii pneumoniaLongitudinal cohort studyRate of deathIntroduction of treatmentTime of deathRates of diseaseAntiretroviral therapyHIV infectionCarinii pneumoniaPregnant womenAntiretroviral drugsHIV-1HIV
1997
Reduction in the Risk of Vertical Transmission of HIV-1 Associated with Treatment of Pregnant Women with Orally Administered Zidovudine Alone
Simpson B, Shapiro E, Andiman W. Reduction in the Risk of Vertical Transmission of HIV-1 Associated with Treatment of Pregnant Women with Orally Administered Zidovudine Alone. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1997, 14: 145-152. PMID: 9052723, DOI: 10.1097/00042560-199702010-00007.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdolescentAdultAnti-HIV AgentsCD4 Lymphocyte CountCohort StudiesDelivery, ObstetricFemaleHIV InfectionsHIV-1HumansInfantInfant, NewbornInfectious Disease Transmission, VerticalLongitudinal StudiesOdds RatioPregnancyPregnancy Complications, InfectiousProspective StudiesRetrospective StudiesRisk FactorsZidovudineConceptsRisk of transmissionT-lymphocyte countsMode of deliveryVertical transmissionHIV-1Cell countT-cell countsProspective cohort studyRisk of motherRoutine prenatal careSubgroup of womenChild transmissionUntreated womenCohort studyUntreated mothersPregnant womenPrenatal careObservational studyCD4ZidovudineSignificant associationWomenMothersRiskSignificant reduction
1996
Lyme Disease in Children in Southeastern Connecticut
Gerber M, Shapiro E, Burke G, Parcells V, Bell G. Lyme Disease in Children in Southeastern Connecticut. New England Journal Of Medicine 1996, 335: 1270-1274. PMID: 8857006, DOI: 10.1056/nejm199610243351703.Peer-Reviewed Original ResearchConceptsErythema migrans lesionsSingle erythema migrans lesionLyme diseaseErythema migransClinical manifestationsMultiple erythema migrans lesionsCommunity-based cohort studyFacial nerve palsyInitial clinical manifestationPrompt clinical responseEarly Lyme diseasePercent of childrenConventional antimicrobial therapyMultiple erythemaClinical responseCohort studyAseptic meningitisConsecutive patientsMedian ageProspective dataAntimicrobial therapyAntibody testNew episodesPatientsLesionsTRENDS IN THE RISK OF VERTICAL TRANSMISSION, MORTALITY, AND AIDS-DEFINING ILLNESSES AMONG CHILDREN OF HIV+ MOTHERS ENROLLED IN A COHORT STUDY, 1985-1995. • 663
Simpson B, Shapiro E, Andiman W. TRENDS IN THE RISK OF VERTICAL TRANSMISSION, MORTALITY, AND AIDS-DEFINING ILLNESSES AMONG CHILDREN OF HIV+ MOTHERS ENROLLED IN A COHORT STUDY, 1985-1995. • 663. Pediatric Research 1996, 39: 113-113. DOI: 10.1203/00006450-199604001-00685.Peer-Reviewed Original Research
1994
Invasive bacterial infections in children born to women infected with human immunodeficiency virus type 1
Andiman W, Mezger J, Shapiro E. Invasive bacterial infections in children born to women infected with human immunodeficiency virus type 1. The Journal Of Pediatrics 1994, 124: 846-852. PMID: 8201465, DOI: 10.1016/s0022-3476(05)83169-5.Peer-Reviewed Original ResearchConceptsInvasive bacterial infectionsHuman immunodeficiency virus type 1Immunodeficiency virus type 1Years of ageVirus type 1Bacterial infectionsHIV-1 infection statusHIV-1-infected mothersHIV-1-infected patientsType 1Instances of bacteremiaSerious focal infectionsObservational cohort studyRate of infectionMonths of ageUninfected subjectsCohort studyPneumococcal bacteremiaInvasive infectionsFocal infectionHIV-1Cerebrospinal fluidS. pneumoniaeHIVStreptococcus pneumoniae
1992
Predictive value of the human immunodeficiency virus 1 antigen test in children born to infected mothers
ANDIMAN W, SILVA T, SHAPIRO E, O'CONNOR T, OLSON B. Predictive value of the human immunodeficiency virus 1 antigen test in children born to infected mothers. The Pediatric Infectious Disease Journal 1992, 11: 436-440. PMID: 1608678, DOI: 10.1097/00006454-199206000-00003.Peer-Reviewed Original ResearchConceptsHIV-1 infectionAntigen testInfected mothersHIV-1Early predictorPositive testPredictive valueHIV-1 infection statusSerial serum samplesLongitudinal cohort studyMonths of lifePositive predictive valueSingle positive testCohort studyInfection statusEnzyme immunoassayFirst monthDiagnostic testsSerum samplesMothersChildrenInfectionMonthsPredictorsPatients