Movies of the Up and Down states - examples of barrages of synaptic activity that propagate through cortical networks

Figure 6. Download and run the movies below to see examples of spontaneous network activity in the cerebral cortex in vivo. Note that the membrane potential of cortical cells exhibits jumps of 10-15 mV in amplitude during this state. The top trace of a frame from each movie shown above is the field potential (EEG), the middle trace is multiple unit activity, and the bottom trace is an intracellular recording from a cortical neuron demonstrating the synaptic (right) and combined synaptic-action potential activity (left) occurring in the anethetized cortex.