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Sunil Parikh, MD, MPH

Professor of Epidemiology (Microbial Diseases) and of Infectious Diseases; Co-Chair Downs Fellowship, Epidemiology of Microbial Diseases

Contact Information

Sunil Parikh, MD, MPH

Lab Location

Office Location

Mailing Address

  • Epidemiology of Microbial Diseases

    60 College Street, P.O. Box 208322

    New Haven, CA 06520

    United States

Research Summary

Dr. Parikh focuses upon several aspects of malaria in sub-Saharan Africa, including studies focused on optimizing treatment regimens, novel chemoprevention strategies, drug resistance emergence and spread, and parasite dynamics. Current projects include: (1) understanding parasite, drug, and host factors affecting response to artemisinin-based antimalarial therapies using a combination of individual and population-based pharmacologic approaches to inform treatment guidelines (Uganda and Burkina Faso); 2) novel use of a endectocides to reduce malaria transmission (Burkina Faso); and 3) characterizing the epidemiology of antimalarial drug resistance and non-falciparum species in sub-Saharan Africa (Burkina Faso and Cameroon). Dr. Parikh has ongoing projects in several African countries, which span observational, interventional, and cross-sectional designs.

Specialized Terms: Translation research in malaria; Pharmacology of antimalarials; HIV-malaria co-infection; Host response to malaria infection; Innate immunity to malaria

Extensive Research Description

1) Antimalarial therapy/efficacy studies in children and those with HIV/malaria co-infection in Uganda

Major Goal: To assess the pharmacokinetics and pharmacodynamics of artemisinin-combination therapies, toxicity of newer antiretrovirals (dolutegravir), and determinants of artemisinin partial drug resistance in two different settings in Uganda.

2) Use of novel approaches to preventing malaria in Burkina Faso

Major Goal: We are conducting a cluster-randomized trial of a novel chemopreventive approach in Burkina Faso

3) Characterizing the epidemiology of malaria species across three different transmission zones in Burkina Faso through longitudinal human cohorts coupled with spatial mapping and mosquito studies (Burkina Faso ICEMR - "PIVOTAL")

4) Development and diagnostic performance studies of a non-invasive diagnostic device for malaria in Cameroon and Burkina Faso.


Research Interests

Africa; Burkina Faso; Cameroon; Developing Countries; Diagnosis; Epidemiology; Malaria; Parasitic Diseases; Public Health; Uganda; Global Health; Infectious Disease Medicine

Public Health Interests

Clinical Trials; Epidemiology Methods; Genetics, Genomics, Epigenetics; Global Health; Immunology; Infectious Diseases; Malaria; Maternal & Child Health; Parasitology; Reproduction; Child/Adolescent Health; COVID-19

Selected Publications