Ariel Jaffe, MD
Assistant Professor of Medicine (Digestive Diseases), Medical Director of Liver Transplant Oncology; Medical Director of Liver Transplant Oncology, Digestive Diseases
Research & Publications
Biography
News
Coauthors
Selected Publications
- Novel updates in the field of HCCJaffe A, Strazzabosco M. Novel updates in the field of HCC. Clinical Liver Disease 2024, 23 PMCID: PMC11078519, DOI: 10.1097/cld.0000000000000142.
- Approach to immunotherapy for HCC in the liver transplant population.Block P, Strazzabosco M, Jaffe A. Approach to immunotherapy for HCC in the liver transplant population. Clinical Liver Disease 2024, 23: e0158. PMID: 38707244, PMCID: PMC11068135, DOI: 10.1097/cld.0000000000000158.
- Artificial intelligence in liver cancer — new tools for research and patient managementCalderaro J, Žigutytė L, Truhn D, Jaffe A, Kather J. Artificial intelligence in liver cancer — new tools for research and patient management. Nature Reviews Gastroenterology & Hepatology 2024, 1-15. PMID: 38627537, DOI: 10.1038/s41575-024-00919-y.
- Automated graded prognostic assessment for patients with hepatocellular carcinoma using machine learningGross M, Haider S, Ze’evi T, Huber S, Arora S, Kucukkaya A, Iseke S, Gebauer B, Fleckenstein F, Dewey M, Jaffe A, Strazzabosco M, Chapiro J, Onofrey J. Automated graded prognostic assessment for patients with hepatocellular carcinoma using machine learning. European Radiology 2024, 1-13. PMID: 38536464, DOI: 10.1007/s00330-024-10624-8.
- Automated MRI liver segmentation for anatomical segmentation, liver volumetry, and the extraction of radiomicsGross M, Huber S, Arora S, Ze’evi T, Haider S, Kucukkaya A, Iseke S, Kuhn T, Gebauer B, Michallek F, Dewey M, Vilgrain V, Sartoris R, Ronot M, Jaffe A, Strazzabosco M, Chapiro J, Onofrey J. Automated MRI liver segmentation for anatomical segmentation, liver volumetry, and the extraction of radiomics. European Radiology 2024, 1-10. PMID: 38217704, DOI: 10.1007/s00330-023-10495-5.
- Community-Level Factors Associated with Hepatocellular Carcinoma Incidence and Mortality: An Observational Registry Study.Mezzacappa C, Rossi R, Jaffe A, Taddei T, Strazzabosco M. Community-Level Factors Associated with Hepatocellular Carcinoma Incidence and Mortality: An Observational Registry Study. Cancer Epidemiology Biomarkers & Prevention 2023, 33: 270-278. PMID: 38059831, PMCID: PMC10872555, DOI: 10.1158/1055-9965.epi-23-0902.
- Advancing diagnosis and management of liver disease in adults through exome sequencingZheng M, Hakim A, Konkwo C, Deaton A, Ward L, Genetics A, Silveira M, Assis D, Liapakis A, Jaffe A, Jiang Z, Curry M, Lai M, Cho M, Dykas D, Bale A, Mistry P, Vilarinho S. Advancing diagnosis and management of liver disease in adults through exome sequencing. EBioMedicine 2023, 95: 104747. PMID: 37566928, PMCID: PMC10433007, DOI: 10.1016/j.ebiom.2023.104747.
- Adherence to Tumor Board Recommendations in the Treatment of Patients with Hepatocellular CarcinomaCao Y, Mezzacappa C, Jaffe A, Strazzabosco M, Taddei T. Adherence to Tumor Board Recommendations in the Treatment of Patients with Hepatocellular Carcinoma. Journal Of Multidisciplinary Healthcare 2023, 16: 1531-1540. PMID: 37283950, PMCID: PMC10239642, DOI: 10.2147/jmdh.s407908.
- Reply: Novel antidiabetic drugs and the risk for HCC. What else to expect from these “wonderful” drug classes?Torres M, Jaffe A, Perry R, Marabotto E, Strazzabosco M, Giannini E. Reply: Novel antidiabetic drugs and the risk for HCC. What else to expect from these “wonderful” drug classes? Hepatology 2023, 77: e184-e185. PMID: 36724446, DOI: 10.1097/hep.0000000000000312.
- Alternative HCC prognostic biomarkers and use of artificial intelligence in the management of HCCJaffe A, Taddei T, Giannini E, Ilagan‐Ying Y, Colombo M, Strazzabosco M. Alternative HCC prognostic biomarkers and use of artificial intelligence in the management of HCC. Liver International 2022, 43: 258-259. PMID: 36426717, DOI: 10.1111/liv.15482.
- Diabetes medications and risk of HCCTorres M, Jaffe A, Perry R, Marabotto E, Strazzabosco M, Giannini EG. Diabetes medications and risk of HCC. Hepatology 2022, 76: 1880-1897. PMID: 35239194, PMCID: PMC9790535, DOI: 10.1002/hep.32439.
- Holistic management of hepatocellular carcinoma: The hepatologist's comprehensive playbookJaffe A, Taddei TH, Giannini EG, Ilagan‐Ying Y, Colombo M, Strazzabosco M. Holistic management of hepatocellular carcinoma: The hepatologist's comprehensive playbook. Liver International 2022, 42: 2607-2619. PMID: 36161463, PMCID: PMC10878125, DOI: 10.1111/liv.15432.
- Metabolic Syndrome and Liver CancerJaffe A, Strazzabosco M. Metabolic Syndrome and Liver Cancer. 2022, 87-104. DOI: 10.1007/978-3-030-41683-6_51.
- Immune checkpoint inhibitors in malignancies after liver transplantation: A systematic review and pooled analysisKayali S, Pasta A, Torres M, Jaffe A, Strazzabosco M, Marenco S, Giannini EG. Immune checkpoint inhibitors in malignancies after liver transplantation: A systematic review and pooled analysis. Liver International 2022, 43: 8-17. PMID: 36102312, PMCID: PMC10087158, DOI: 10.1111/liv.15419.
- Optimization of the BCLC Staging System for Locoregional Therapy for Hepatocellular Carcinoma by Using Quantitative Tumor Burden Imaging Biomarkers at MRI.Borde T, Nezami N, Laage Gaupp F, Savic LJ, Taddei T, Jaffe A, Strazzabosco M, Lin M, Duran R, Georgiades C, Hong K, Chapiro J. Optimization of the BCLC Staging System for Locoregional Therapy for Hepatocellular Carcinoma by Using Quantitative Tumor Burden Imaging Biomarkers at MRI. Radiology 2022, 304: 228-237. PMID: 35412368, PMCID: PMC9270683, DOI: 10.1148/radiol.212426.
- Improved performance and consistency of deep learning 3D liver segmentation with heterogeneous cancer stages in magnetic resonance imagingGross M, Spektor M, Jaffe A, Kucukkaya AS, Iseke S, Haider SP, Strazzabosco M, Chapiro J, Onofrey JA. Improved performance and consistency of deep learning 3D liver segmentation with heterogeneous cancer stages in magnetic resonance imaging. PLOS ONE 2021, 16: e0260630. PMID: 34852007, PMCID: PMC8635384, DOI: 10.1371/journal.pone.0260630.
- Metabolic Syndrome and Liver CancerJaffe A, Strazzabosco M. Metabolic Syndrome and Liver Cancer. 2021, 1-19. DOI: 10.1007/978-3-030-37482-2_51-1.
- Reliable prediction of survival in advanced-stage hepatocellular carcinoma treated with sorafenib: comparing 1D and 3D quantitative tumor response criteria on MRIDoemel LA, Chapiro J, Laage Gaupp F, Savic LJ, Kucukkaya AS, Petukhova A, Tefera J, Zeevi T, Lin M, Schlachter T, Jaffe A, Strazzabosco M, Patel T, Stein SM. Reliable prediction of survival in advanced-stage hepatocellular carcinoma treated with sorafenib: comparing 1D and 3D quantitative tumor response criteria on MRI. European Radiology 2020, 31: 2737-2746. PMID: 33123796, PMCID: PMC8043967, DOI: 10.1007/s00330-020-07381-9.
- Health related quality of life in chronic liver diseasesCortesi PA, Conti S, Scalone L, Jaffe A, Ciaccio A, Okolicsanyi S, Rota M, Fabris L, Colledan M, Fagiuoli S, Belli LS, Cesana G, Strazzabosco M, Mantovani LG. Health related quality of life in chronic liver diseases. Liver International 2020, 40: 2630-2642. PMID: 32851764, DOI: 10.1111/liv.14647.
- Liver Transplantation in the Time of COVID19: Barriers and Ethical Considerations for Management and Next StepsJaffe A, Schilsky ML, Deshpande R, Batra R. Liver Transplantation in the Time of COVID19: Barriers and Ethical Considerations for Management and Next Steps. Hepatology Communications 2020, 4: 1242-1256. PMID: 32838103, PMCID: PMC7361607, DOI: 10.1002/hep4.1568.
- Randomized near-neighbor graphs, giant components and applications in data scienceJaffe A, Kluger Y, Linderman G, Mishne G, Steinerberger S. Randomized near-neighbor graphs, giant components and applications in data science. Journal Of Applied Probability 2020, 57: 458-476. PMID: 32913373, PMCID: PMC7480951, DOI: 10.1017/jpr.2020.21.
- Pathophysiology of Hepatic EncephalopathyJaffe A, Lim JK, Jakab SS. Pathophysiology of Hepatic Encephalopathy. Clinics In Liver Disease 2020, 24: 175-188. PMID: 32245525, DOI: 10.1016/j.cld.2020.01.002.
- Bile‐Derived Organoids From Patients With Primary Sclerosing Cholangitis Recapitulate Their Inflammatory Immune ProfileSoroka CJ, Assis DN, Alrabadi LS, Roberts S, Cusack L, Jaffe AB, Boyer JL. Bile‐Derived Organoids From Patients With Primary Sclerosing Cholangitis Recapitulate Their Inflammatory Immune Profile. Hepatology 2019, 70: 871-882. PMID: 30561836, DOI: 10.1002/hep.30470.
- The discrete sign problem: Uniqueness, recovery algorithms and phase retrieval applicationsLeshem B, Raz O, Jaffe A, Nadler B. The discrete sign problem: Uniqueness, recovery algorithms and phase retrieval applications. Applied And Computational Harmonic Analysis 2018, 45: 463-485. DOI: 10.1016/j.acha.2016.12.003.
- Determinants of Follow-up Care for Patients With Celiac Disease.Cohen ME, Jaffe A, Strauch CB, Lewis SK, Lebwohl B, Green PHR. Determinants of Follow-up Care for Patients With Celiac Disease. Journal Of Clinical Gastroenterology 2018, 52: 784-788. PMID: 28723859, DOI: 10.1097/MCG.0000000000000851.
- A Review of Antiviral Use for the Treatment of Chronic Hepatitis B Virus Infection in Pregnant Women.Jaffe A, Brown RS. A Review of Antiviral Use for the Treatment of Chronic Hepatitis B Virus Infection in Pregnant Women. Gastroenterology & Hepatology 2017, 13: 154-163. PMID: 28539842, PMCID: PMC5439134.