Edward Doherty
Associate Research Scientist (Rheumatology, Allergy & Immunology)Cards
Appointments
Rheumatology
Primary
About
Titles
Associate Research Scientist (Rheumatology, Allergy & Immunology)
Appointments
Rheumatology
Associate Research ScientistPrimary
Other Departments & Organizations
Research
Publications
2010
Expansion of CD3+/CD4+/CD25+/Foxp3+ T cells in rapamycin-treated lupus patients (143.52)
Perl A, Lai Z, Telarico T, Bartos A, Miklossy G, Hanczko R, Francis L, Tily H, Ramos I, Garcia R, Phillips P, Jimah J, Doherty E. Expansion of CD3+/CD4+/CD25+/Foxp3+ T cells in rapamycin-treated lupus patients (143.52). The Journal Of Immunology 2010, 184: 143.52-143.52. DOI: 10.4049/jimmunol.184.supp.143.52.Peer-Reviewed Original ResearchConceptsSLE patientsT cellsLupus patientsSystemic lupus erythematosus patientsMitochondrial hyperpolarizationFemale SLE patientsFrequency of TregsPrevalence of Foxp3Lupus erythematosus patientsT cell activationSLEDAI scoreHealthy controlsVivo treatmentPatientsB cellsFemale controlsTherapeutic efficacyCell activationMammalian targetVivo expansionMTOR activityRapamycin treatmentPotential mechanismsTregsRapamycin