Marta Piecychna

Research Assistant Internal Medicine Rheumatology

Contact Info

marta.piecychna@yale.edu

About

Titles

Research Assistant Internal Medicine Rheumatology

Departments & Organizations

Internal Medicine

Research

Research at a Glance

Yale Co-Authors

Frequent collaborators of Marta Piecychna's published research.

Richard Bucala, MD, PhD
View Full Profile
View 5 Common Publications
Lin Leng
Former YSM
View 4 Common Publications
Insoo Kang, MD
View Full Profile
View 2 Common Publications
Lais Osmani, MD, MHS
View Full Profile
View 2 Common Publications
Thuy Tran, MD, PhD
View Full Profile
View 2 Common Publications
Buqu Hu
View Full Profile
View Common Publication

Publications

2026

Pathogenic role of MIF receptor (CD74) expressing T cells in inflammatory arthritis
Doherty E, Osmani L, Bilsborrow J, Par-Young J, Choi S, Tilstam P, Shin M, Piecychna M, Cai H, Leng L, Kim W, Kang I, Bucala R. Pathogenic role of MIF receptor (CD74) expressing T cells in inflammatory arthritis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2026, 123: e2509156123. PMID: 41505516, PMCID: PMC12799170, DOI: 10.1073/pnas.2509156123.
Peer-Reviewed Original Research
MeSH Keywords

2025

Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling
Kim S, Nouws J, Ruwisch J, Woodard G, Cooley J, Khoury J, Sun H, Doherty E, Piecychna M, Manning E, Kang M, Bruscia E, Wei H, Zhang Y, Yarovinsky T, Hwa J, Zacharias W, Ingram J, Lee C, Elias J, Kaminski N, Redente E, Herzog E, Prasse A, Bucala R, Sauler M. Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling. Science Translational Medicine 2025, 17: eadr2277. PMID: 41337540, DOI: 10.1126/scitranslmed.adr2277.
Peer-Reviewed Original Research
MeSH Keywords
Improving immunotherapy responses by dual inhibition of macrophage migration inhibitory factor and PD-1
Tran T, Sánchez-Zuno G, Osmani L, Caulfield J, Valdez C, Piecychna M, Leng L, Armstrong M, Donnelly S, Bifulco C, Clister T, Kulkarni R, Zhang L, Sznol M, Jilaveanu L, Kluger H, Kang I, Bucala R. Improving immunotherapy responses by dual inhibition of macrophage migration inhibitory factor and PD-1. JCI Insight 2025, 10: e191539. PMID: 41122966, PMCID: PMC12581657, DOI: 10.1172/jci.insight.191539.
Peer-Reviewed Original Research
MeSH Keywords

2024

CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells
Pellegrino B, David K, Rabani S, Lampert B, Tran T, Doherty E, Piecychna M, Meza-Romero R, Leng L, Hershkovitz D, Vandenbark A, Bucala R, Becker-Herman S, Shachar I. CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells. PLOS Biology 2024, 22: e3002905. PMID: 39576827, PMCID: PMC11623796, DOI: 10.1371/journal.pbio.3002905.
Peer-Reviewed Original Research
A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus
Li J, Leng L, Pantouris G, Manjula R, Piecychna M, Abriola L, Hu B, Lolis E, Armstrong M, Donnelly S, Bucala R. A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus. Journal Of Biological Chemistry 2024, 300: 107443. PMID: 38838773, PMCID: PMC11259703, DOI: 10.1016/j.jbc.2024.107443.
Peer-Reviewed Original Research

News

Get In Touch

Contacts

marta.piecychna@yale.edu

Marta Piecychna

Contact Info

About

Titles

Departments & Organizations

Research

Research at a Glance

Yale Co-Authors

Richard Bucala, MD, PhD

Lin Leng

Insoo Kang, MD

Lais Osmani, MD, MHS

Thuy Tran, MD, PhD

Buqu Hu

Publications

2026

Pathogenic role of MIF receptor (CD74) expressing T cells in inflammatory arthritis

2025

Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor–CD74 signaling

Improving immunotherapy responses by dual inhibition of macrophage migration inhibitory factor and PD-1

2024

CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells

A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus

News

News

New Yale Study Reveals Mechanism Behind Persistent Autoimmune Joint Destruction

Yale Researchers Pave Way To Target Autoimmune Disease-associated Gene Variant

Internal Medicine Staff Celebrated for Service Anniversaries

How A Common Gene Variant Influences Your Risk of Severe Illness From COVID-19

Get In Touch

Contacts