Abigail Demuyakor, MD, PhD
Associate Research ScientistCards
About
Research
Publications
2025
TCT-438 Comparison of Coronary Vessel Sizing by Artificial Intelligence-Based Coronary Computed Tomography Angiography Quantification and Intravascular Ultrasound: Insights from the INVICTUS Registry
Demuyakor A, Nakanishi R, Pandya R, Okubo R, Matsuo H, Sato H, Fujimoto S, Kajiya T, Miyoshi T, Ichikawa K, Abe M, Kitagawa T, Ikenaga H, Osawa K, Saji M, Nakazawa G, Takahashi K, Ijichi T, Mikamo H, Kurata A, Moroi M, Bandeira D, Lansky A, Mintz G, Chamie D. TCT-438 Comparison of Coronary Vessel Sizing by Artificial Intelligence-Based Coronary Computed Tomography Angiography Quantification and Intravascular Ultrasound: Insights from the INVICTUS Registry. Journal Of The American College Of Cardiology 2025, 86: b192. DOI: 10.1016/j.jacc.2025.09.558.Peer-Reviewed Original ResearchCan AI Capture and Quantify Clinical Expertise? Implications for Intracoronary Imaging in Percutaneous Coronary Intervention
1Peer-Reviewed Original ResearchCan AI Capture and Quantify Clinical Expertise? Implications for Intracoronary Imaging in Percutaneous Coronary Intervention
Petraco R, Bahl R, Almeida G, Bandeira D, Seligman H, Alloula A, Demuyakor A, Lansky A, Johnson T, Francis D, Mintz G, Shun-Shin M, Chamié D. Can AI Capture and Quantify Clinical Expertise? Implications for Intracoronary Imaging in Percutaneous Coronary Intervention. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 102523. PMID: 40230670, PMCID: PMC11993851, DOI: 10.1016/j.jscai.2024.102523.Peer-Reviewed Original Research
2024
Optimal Threshold For Characterizing Calcified Plaque On Ccta As Determined By Correlation With Oct
Chamie D, Okubo R, Sobue Y, Kaneko U, Sato H, Fujimoto S, Nozaki Y, Kajiya T, Miyoshi T, Ichikawa K, Abe M, Kitagawa T, Ikenaga H, Osawa K, Saji M, Iguchi N, Nakazawa G, Takahashi K, Ijich T, Mikamo H, Kurata A, Moroi M, Iijima R, Lansky A, Demuyakor A, Matsuo H, Hoffmann U, Min J, Earls J, Nakanishi R. Optimal Threshold For Characterizing Calcified Plaque On Ccta As Determined By Correlation With Oct. Journal Of Cardiovascular Computed Tomography 2024, 18: s80. DOI: 10.1016/j.jcct.2024.05.189.Peer-Reviewed Original Research
2023
Pancoronary plaque characteristics and clinical outcomes in acute coronary syndrome patients with cancer history
Wang C, Tian X, Feng X, Demuyakor A, Hu S, Wang Y, Li L, Cui L, Dong F, Dai J, Lei F, Xu Y, Du Z, Shi M, Liu J, Xing L, E M. Pancoronary plaque characteristics and clinical outcomes in acute coronary syndrome patients with cancer history. Atherosclerosis 2023, 378: 117118. PMID: 37127496, DOI: 10.1016/j.atherosclerosis.2023.03.023.Peer-Reviewed Original ResearchConceptsAcute coronary syndrome patientsAcute coronary syndromeMaximum lipid arcOptical coherence tomographyThin-cap fibroatheromaCancer historyFibrous cap thicknessPercutaneous coronary interventionNonculprit lesionsLipid arcPrevalence of high-risk plaqueIncidence of thin-cap fibroatheromaCulprit lesionPrevalence of acute coronary syndromeHigh-risk plaque featuresHigher incidencePlaque characteristicsTime of percutaneous coronary interventionAssociated with high mortalityCharacteristics of coronary plaquesLipid indicesAbsence of cancer historyCoronary syndrome patientsNon-culprit lesionsIncidence of calcification
2022
Clinical Characteristics and Prognosis of MINOCA Caused by Atherosclerotic and Nonatherosclerotic Mechanisms Assessed by OCT
Zeng M, Zhao C, Bao X, Liu M, He L, Xu Y, Meng W, Qin Y, Weng Z, Yi B, Zhang D, Wang S, Luo X, Lv Y, Chen X, Sun Q, Feng X, Gao Z, Sun Y, Demuyakor A, Li J, Hu S, Guagliumi G, Mintz G, Jia H, Yu B. Clinical Characteristics and Prognosis of MINOCA Caused by Atherosclerotic and Nonatherosclerotic Mechanisms Assessed by OCT. JACC Cardiovascular Imaging 2022, 16: 521-532. PMID: 36648054, DOI: 10.1016/j.jcmg.2022.10.023.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsOptical coherence tomographyTarget lesion revascularizationCardiac deathLesion revascularizationPredictors of Major Adverse Cardiac EventsAssociated with worse outcomesSpontaneous coronary artery dissectionClinical diagnosis of MIPrognosis of MINOCAMechanisms of MINOCAAdverse cardiac eventsNonobstructive coronary arteriesPrognosis of patientsCoronary artery dissectionDiagnosis of MIOCT findingsAtherosclerotic causeCardiac eventsClinical characteristicsClinical outcomesArtery dissectionComposite endpointMINOCACoronary spasmImpact of nodular calcification in patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI)
Demuyakor A, Hu S, Koniaeva E, Liu M, Weng Z, Zhao C, Feng X, He L, Xu Y, Zeng M, Meng W, Sun Y, Yi B, Gao Z, Qin Y, Jia H, Mintz G, Yu B. Impact of nodular calcification in patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI). BMC Cardiovascular Disorders 2022, 22: 103. PMID: 35287572, PMCID: PMC8922875, DOI: 10.1186/s12872-022-02551-7.Peer-Reviewed Original ResearchConceptsAcute coronary syndromePercutaneous coronary interventionPrimary percutaneous coronary interventionCalcification groupOptical coherence tomographyNodular calcificationStent under-expansionCoronary interventionCoronary syndromeLower left ventricular ejection fractionPresence of nodular calcificationTreated with primary percutaneous coronary interventionUnder-expansionCulprit plaquesVentricular ejection fractionMinimum stent areaEjection fractionProtruding massCoherence tomographyWell-delineated borderPatientsStent areaCalcificationImpact outcomesSignal attenuation
2021
Impact of nodular calcification on the outcomes of patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI)
Demuyakor A, Hu S, Koniaeva E, Liu M, Weng Z, Zhao C, Feng X, He L, Xu Y, Zeng M, Meng W, Yi B, Qin Y, Jia H, Bo Y. Impact of nodular calcification on the outcomes of patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI). European Heart Journal 2021, 42: ehab724.1249. DOI: 10.1093/eurheartj/ehab724.1249.Peer-Reviewed Original ResearchAcute coronary syndromePercutaneous coronary interventionPrimary percutaneous coronary interventionOutcomes of patientsCalcification groupOptical coherence tomographyNodular calcificationCoronary syndromeMinimum stent areaCoronary interventionLower left ventricular ejection fractionPresence of nodular calcificationTreated with primary percutaneous coronary interventionAssociated with unfavourable outcomeIncidence of stentsAcute coronary syndrome patientsVentricular ejection fractionLesion lengthImpact clinical outcomesEjection fractionIndependent predictorsProtruding massClinical outcomesUnfavourable outcomeResults PatientsPredictors of non-stenting strategy for acute coronary syndrome caused by plaque erosion: four-year outcomes of the EROSION study.
He L, Qin Y, Xu Y, Hu S, Wang Y, Zeng M, Feng X, Liu Q, Syed I, Demuyakor A, Zhao C, Chen X, Li Z, Meng W, Xu M, Liu H, Ma L, Dai J, Xing L, Yu H, Hou J, Jia H, Mintz G, Yu B. Predictors of non-stenting strategy for acute coronary syndrome caused by plaque erosion: four-year outcomes of the EROSION study. EuroIntervention 2021, 17: 497-505. PMID: 33164894, PMCID: PMC9724919, DOI: 10.4244/eij-d-20-00299.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeNon-TLR groupLong-term prognosisOptical coherence tomographyFollow-upAntithrombotic therapyCoronary syndromePredictor of long-term prognosisResponse to antithrombotic therapyTreated with antithrombotic therapyPlaque erosionLong-term follow-upTarget lesion revascularisationMedian durationPrimary endpointAntithrombotic strategiesOne-month follow-upThrombus reductionGastrointestinal bleedingAngiographic resultsCoherence tomographyStent implantationDiameter stenosisClinic visitsPatientsIs the effect of atorvastatin 60 mg on stabilization of lipid‐rich plaque equivalent to that of rosuvastatin 10 mg? A serial optical coherence tomography combined with intravascular ultrasound imaging
Xu M, Demuyakor A, Hu S, Liu H, Zhao C, Chen T, Qin Y, Xu Y, Feng X, Zeng M, Weng Z, Gao Z, Hou J, Jia H, Zhang S, Yu B. Is the effect of atorvastatin 60 mg on stabilization of lipid‐rich plaque equivalent to that of rosuvastatin 10 mg? A serial optical coherence tomography combined with intravascular ultrasound imaging. Catheterization And Cardiovascular Interventions 2021, 97: 1097-1107. PMID: 33864710, DOI: 10.1002/ccd.29654.Peer-Reviewed Original ResearchConceptsOptical coherence tomographyLipid-rich plaquesLipid lowering therapyEffect of atorvastatinFibrous cap thicknessStatin therapyLowering therapyCoherence tomographyIntensive lipid lowering therapySerial optical coherence tomographyCholesterol levelsLow-density lipoprotein cholesterol levelsIntravascular ultrasound imagingLipoprotein cholesterol levelsCholesterol level reductionLipid arcClinical benefitFollow-upPlaque volumeUltrasound imagingTherapyTherapy effectsPlaque burdenPercentage changeStatins
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Yale School of Medicine
135 College Street,
New Haven, Connecticut 06510
United States