2025
Five-year outcomes after surgical treatment of infant postinfectious hydrocephalus in sub-Saharan Africa: results of a randomized trial.
Mbabazi-Kabachelor E, Peterson M, Mugamba J, Ssenyonga P, Onen J, Nalule E, Magombe J, Cherukuri V, Monga V, Schiff S, Kulkarni A, Warf B. Five-year outcomes after surgical treatment of infant postinfectious hydrocephalus in sub-Saharan Africa: results of a randomized trial. Journal Of Neurosurgery Pediatrics 2025, 1-10. PMID: 40315611, DOI: 10.3171/2025.1.peds24417.Peer-Reviewed Original ResearchHydrocephalus Outcome QuestionnairePostinfectious hydrocephalusVABS-3HOQ scoresBrain volumeVentriculoperitoneal shuntRandomized trialsQuality of lifeAssessed developmental outcomesPerinatal neurologic insultChoroid plexus cauterizationSurgical treatment armHUI-3Endoscopic third ventriculostomyVentriculoperitoneal shunt treatmentVineland Adaptive Behavior ScalesFollow-up resultsLong-term outcomesFive-year outcomesBrain volume outcomesQuality of life metricsAdaptive Behavior ScalesPublic health burdenSub-Saharan AfricaTreatment failureQualitative evaluation of meaningful change in Dravet syndrome as measured by the Vineland-3: Caregiver and clinician perspectives
Condon C, Parkerson K, Dandurand A, Wang F, Howse C, Mayhew M, Whyman S, Ventola P, Anne Meskis M, Sullivan J, Knupp K, Gater A, Mahon-Smith A. Qualitative evaluation of meaningful change in Dravet syndrome as measured by the Vineland-3: Caregiver and clinician perspectives. Epilepsy & Behavior 2025, 167: 110381. PMID: 40188607, DOI: 10.1016/j.yebeh.2025.110381.Peer-Reviewed Original ResearchConceptsVineland-3Presence of autism spectrum disorderVineland Adaptive Behavior ScalesAdaptive Behavior ScalesAutism spectrum disorderDravet syndromeCaregivers of children/adolescentsDisruptive behaviorSpectrum disorderBehavior ScaleClinical expertsClinically meaningful changeAdaptive behaviorReceptive communicationImpaired communicationThird editionAnchor-based methodsSemi-structured interviewsTreatment-related benefitsCaregiver feedbackClinician perspectivesMeaningful changePatient independenceCaregiversQualitative study
2020
Long-Term Neurobehavioral and Quality of Life Outcomes of Critically Ill Children after Glycemic Control
Biagas K, Hinton V, Hasbani N, Luckett P, Wypij D, Nadkarni V, Agus M, investigators H, Srinivasan V, Mourani P, Chima R, Thomas N, Li S, Pinto A, Newth C, Hassinger A, Bysani K, Rehder K, Faustino E, Kandil S, Hirshberg E, Wintergerst K, Schwarz A, Bagdure D, Marsillio L, Cvijanovich N, Pham N, Quasney M, Flori H, Federman M, Nett S, Pinto N, Viteri S, Schneider J, Medar S, Sapru A, McQuillen P, Babbitt C, Lin J, Jouvet P, Yanay O, Allen C, Asaro L, Coughlin-Wells K, French J, Natarajan A, Network T. Long-Term Neurobehavioral and Quality of Life Outcomes of Critically Ill Children after Glycemic Control. The Journal Of Pediatrics 2020, 218: 57-63.e5. PMID: 31910992, PMCID: PMC7122648, DOI: 10.1016/j.jpeds.2019.10.055.Peer-Reviewed Original ResearchConceptsHealth-related qualityHigher-target groupGlycemic controlLife outcomesIll childrenPediatric QualityProspective longitudinal cohort studyIntensive care dischargeTarget glycemic controlTight glycemic controlLongitudinal cohort studyRisk of mortalityLack of benefitRespiratory failureCohort studyHospital dischargeInsulin titrationSecondary outcomesPrimary outcomeCare dischargeEligible childrenChild Behavior ChecklistOverall healthTotal healthVineland Adaptive Behavior Scales
2019
Sensory-to-Cognitive Systems Integration Is Associated With Clinical Severity in Autism Spectrum Disorder
Martínez K, Martínez-García M, Marcos-Vidal L, Janssen J, Castellanos F, Pretus C, Villarroya Ó, Pina-Camacho L, Díaz-Caneja C, Parellada M, Arango C, Desco M, Sepulcre J, Carmona S. Sensory-to-Cognitive Systems Integration Is Associated With Clinical Severity in Autism Spectrum Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 422-433. PMID: 31260788, DOI: 10.1016/j.jaac.2019.05.033.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderAutism spectrum disorder groupHigh-functioning ASD individualsResting state functional magnetic resonance imagingFunctional magnetic resonance imagingHealthy controlsVineland Adaptive Behavior ScalesUnimodal regionsImpaired multisensory integrationAssociated with increased clinical severityMultisensory integration deficitsAdaptive Behavior ScalesFunctional connectivity analysisSocial Communication QuestionnaireSocial Responsiveness ScalePatterns of hyper-Connection integrityMultimodal sensory integrationFunctional dysconnectivityBrain systemsASD groupMode networkFronto-parietalHigh-functioning
2018
Amygdala functional connectivity is associated with social impairments in preterm born young adults
Johns CB, Lacadie C, Vohr B, Ment LR, Scheinost D. Amygdala functional connectivity is associated with social impairments in preterm born young adults. NeuroImage Clinical 2018, 21: 101626. PMID: 30545688, PMCID: PMC6413301, DOI: 10.1016/j.nicl.2018.101626.Peer-Reviewed Original ResearchConceptsVineland Adaptive Behavior ScalesYouth Self-ReportAmygdala functional connectivitySocial impairmentChild Behavior ChecklistFunctional connectivityAmygdala connectivityPreterm participantsSocial functioningSocial functioning correlatesSocial functioning deficitsResting-state functional magnetic resonanceFunctional magnetic resonancePreterm-born adolescentsAdaptive Behavior ScalesAge 16Term-born peersEmotional developmentPreterm birth experienceParent reportDevelopmental trajectoriesRisk of depressionLate adolescentsBehavior ChecklistSelf-Report
2017
Arbaclofen in fragile X syndrome: results of phase 3 trials
Berry-Kravis E, Hagerman R, Visootsak J, Budimirovic D, Kaufmann W, Cherubini M, Zarevics P, Walton-Bowen K, Wang P, Bear M, Carpenter R. Arbaclofen in fragile X syndrome: results of phase 3 trials. Journal Of Neurodevelopmental Disorders 2017, 9: 3. PMID: 28616094, PMCID: PMC5467054, DOI: 10.1186/s11689-016-9181-6.Peer-Reviewed Original ResearchClinical Global Impression-ImprovementFragile X syndromeClinical Global Impression-SeveritySocial avoidanceABC-CFXAberrant Behavior Checklist-Community EditionHigh dose groupAnimal models of fragile X syndromeX syndromeModel of fragile X syndromeVineland Adaptive Behavior ScalesEffect sizeFlexible dose trialSerotonin reuptake inhibitorsSocial Avoidance subscaleChild studiesAdaptive Behavior ScalesAdolescent/adult studyFixed dose trialsDose groupParenting Stress IndexPhase 3 placebo-controlled trialsPreclinical models to clinical trialsResults of phase 3 trialsDose trial
2016
Non‐ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study
Charman T, Young GS, Brian J, Carter A, Carver LJ, Chawarska K, Curtin S, Dobkins K, Elsabbagh M, Georgiades S, Hertz‐Picciotto I, Hutman T, Iverson JM, Jones EJ, Landa R, Macari S, Messinger DS, Nelson CA, Ozonoff S, Saulnier C, Stone WL, Tager‐Flusberg H, Webb SJ, Yirmiya N, Zwaigenbaum L. Non‐ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study. Autism Research 2016, 10: 169-178. PMID: 27417857, PMCID: PMC5993543, DOI: 10.1002/aur.1669.Peer-Reviewed Original ResearchConceptsAutism Diagnostic Observation ScheduleAutism spectrum disorderHigh-risk siblingsLow-risk controlsBroader autism phenotypeModerate language delayAdaptive functioningASD symptomsLanguage delayVineland Adaptive Behavior ScalesLower adaptive functioningAge 3 yearsAutism Diagnostic InterviewProportion of toddlersAdaptive behavior outcomesAdaptive Behavior ScalesOngoing clinical monitoringAutism phenotypeMullen ScalesSpectrum disorderObservation ScheduleEarly learningBehavioral outcomesElevated scoresDevelopmental outcomes
2011
Adaptive Behavior in Toddlers Under Two with Autism Spectrum Disorders
Paul R, Loomis R, Chawarska K. Adaptive Behavior in Toddlers Under Two with Autism Spectrum Disorders. Journal Of Autism And Developmental Disorders 2011, 44: 264-270. PMID: 21573835, DOI: 10.1007/s10803-011-1279-9.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderVineland Adaptive Behavior ScalesAdaptive Behavior ScalesNonverbal developmentNonverbal abilityDevelopmental delayAutistic symptomsReceptive communicationBehavior ScaleAdaptive behaviorCommunication scoresAge 2Algorithm scoresToddlersClinical implicationsAreas of differenceCognitionDaily livingDisordersDD pairsScoresVinelandPeersCorrelation analysis
2005
Adaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder
Sukhodolsky DG, do Rosario-Campos MC, Scahill L, Katsovich L, Pauls DL, Peterson BS, King RA, Lombroso PJ, Findley DB, Leckman JF. Adaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder. American Journal Of Psychiatry 2005, 162: 1125-1132. PMID: 15930061, PMCID: PMC2291297, DOI: 10.1176/appi.ajp.162.6.1125.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdolescentAttention Deficit Disorder with HyperactivityChildComorbidityCross-Sectional StudiesDiagnostic and Statistical Manual of Mental DisordersEmotionsFamily HealthFemaleHealth StatusHumansMaleObsessive-Compulsive DisorderPersonality InventoryPsychiatric Status Rating ScalesSurveys and QuestionnairesConceptsAttention deficit hyperactivity disorderObsessive-compulsive disorderComorbid attention deficit hyperactivity disorderDiagnosis of OCDDeficit hyperactivity disorderFamily functioningEmotional adjustmentHyperactivity disorderVineland Adaptive Behavior ScalesSelf-reported anxietyDaily living skillsAdaptive Behavior ScalesAdolescents ages 7Self-reported depressionBest-estimate DSM-IV diagnosesGroup of childrenAdaptive functioningLevel of impairmentChild functioningParent ratingsComparison childrenEmotional functioningComprehensive batteryLiving skillsDSM-IV diagnosisRisperidone for the Core Symptom Domains of Autism: Results From the Study by the Autism Network of the Research Units on Pediatric Psychopharmacology
McDougle CJ, Scahill L, Aman MG, McCracken JT, Tierney E, Davies M, Arnold LE, Posey DJ, Martin A, Ghuman JK, Shah B, Chuang SZ, Swiezy NB, Gonzalez NM, Hollway J, Koenig K, McGough JJ, Ritz L, Vitiello B. Risperidone for the Core Symptom Domains of Autism: Results From the Study by the Autism Network of the Research Units on Pediatric Psychopharmacology. American Journal Of Psychiatry 2005, 162: 1142-1148. PMID: 15930063, DOI: 10.1176/appi.ajp.162.6.1142.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAntipsychotic AgentsAutistic DisorderChildCommunication DisordersConduct DisorderDouble-Blind MethodFemaleHumansInterpersonal RelationsMalePersonality InventoryPlacebosPsychiatric Status Rating ScalesRisperidoneStereotyped BehaviorStereotypic Movement DisorderTreatment OutcomeConceptsYale-Brown Obsessive Compulsive ScaleChildren's Yale-Brown Obsessive Compulsive ScaleRitvo-Freeman Real Life Rating ScaleObsessive Compulsive ScaleBehavior domainsVineland Adaptive Behavior ScalesCompulsive ScaleCore symptom domainsAdaptive Behavior ScalesSensory-motor behaviorsSelf-injurious behaviorCommunicative impairmentsAutistic childrenSocial relatednessAutism NetworkRating ScaleCommunication impairmentsSevere tantrumsCore symptomsBehavior ScaleSocial interactionAutistic disorderAutismSymptom domainsLife Rating Scale
2003
Disruptive Behavior in Children With Tourette's Syndrome: Association With ADHD Comorbidity, Tic Severity, and Functional Impairment
SUKHODOLSKY DG, SCAHILL L, ZHANG H, PETERSON BS, KING RA, LOMBROSO PJ, KATSOVICH L, FINDLEY D, LECKMAN JF. Disruptive Behavior in Children With Tourette's Syndrome: Association With ADHD Comorbidity, Tic Severity, and Functional Impairment. Journal Of The American Academy Of Child & Adolescent Psychiatry 2003, 42: 98-105. PMID: 12500082, DOI: 10.1097/00004583-200301000-00016.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderComorbid attention-deficit/hyperactivity disorderDisruptive behaviorFamily functioningParent ratingsTeacher ratingsDiagnosis of ADHDVineland Adaptive Behavior ScalesDisruptive behavior problemsHierarchical regression analysisAdaptive Behavior ScalesBest-estimate DSM-IV diagnosesUnaffected control childrenTourette syndromeConduct problemsDelinquency scoresHyperactivity disorderADHD comorbidityDelinquent behaviorBehavior problemsDSM-IV diagnosisDependent measuresDiagnostic statusBehavior ScaleFunctional impairment
2002
Toward a Developmental Operational Definition of Autism
Gillham J, Carter A, Volkmar F, Sparrow S. Toward a Developmental Operational Definition of Autism. 2002, 363-382. DOI: 10.4324/9780203449523-18.Peer-Reviewed Original ResearchDevelopmental disordersVineland Adaptive Behavior ScalesTraditional diagnostic schemeAdaptive Behavior ScalesPervasive developmental disorderMental ageAutism groupAdaptive skillsIntellectual functioningMaladaptive behaviorsVineland scoresDevelopmental levelBehavior ScaleAutismSocialization scoresChronological ageExamination of childrenOperational definitionChildrenDisordersPDDNOSMeasuresFunctioningSkillsScores
2000
Toward a Developmental Operational Definition of Autism
Gillham J, Carter A, Volkmar F, Sparrow S. Toward a Developmental Operational Definition of Autism. Journal Of Autism And Developmental Disorders 2000, 30: 269-278. PMID: 11039854, DOI: 10.1023/a:1005571115268.Peer-Reviewed Original ResearchConceptsMental ageSocialization scoresChronological ageDevelopmental disordersVineland Adaptive Behavior ScalesLarge normative sampleDaily living skillsAdaptive behavior scoresTraditional diagnostic schemeDiagnosis of autismAdaptive Behavior ScalesAutism groupIntellectual functioningNormative sampleMaladaptive behaviorsChild communicationVineland scoresDevelopmental levelBasis of socializationSerious maladaptive behaviorsLiving skillsStandardized measuresAutismBehavior ScaleAdaptive behavior
1998
The Vineland Adaptive Behavior Scales: Supplementary Norms for Individuals with Autism
Carter A, Volkmar F, Sparrow S, Wang J, Lord C, Dawson G, Fombonne E, Loveland K, Mesibov G, Schopler E. The Vineland Adaptive Behavior Scales: Supplementary Norms for Individuals with Autism. Journal Of Autism And Developmental Disorders 1998, 28: 287-302. PMID: 9711485, DOI: 10.1023/a:1026056518470.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdaptation, PsychologicalAdolescentAdultAnalysis of VarianceAutistic DisorderChildChild DevelopmentChild, PreschoolChi-Square DistributionCommunication DisordersDisability EvaluationFemaleHumansIntellectual DisabilityMaleMiddle AgedMotor SkillsMutismPsychiatric Status Rating ScalesPsychometricsReference ValuesSampling StudiesSocial BehaviorConceptsDaily living skillsMute individualsVerbal individualsVerbal skillsLiving skillsStandard scoresVineland Adaptive Behavior ScalesHigher standard scoresAdaptive Behavior ScalesPopulation normsVineland domainsVerbal childrenAutistic individualsMute childrenBehavior ScaleAutismGroup of individualsCommunication domainYoung childrenRelative weaknessYears of ageSkillsHigher scoresNational normsOlder individuals
1993
Quantifying Social Development in Autism
VOLKMAR F, CARTER A, SPARROW S, CICCHETTI D. Quantifying Social Development in Autism. Journal Of The American Academy Of Child & Adolescent Psychiatry 1993, 32: 627-632. PMID: 7684364, DOI: 10.1097/00004583-199305000-00020.Peer-Reviewed Original ResearchConceptsSocial skillsVineland Adaptive Behavior ScalesSocial developmentDaily living skillsAdaptive Behavior ScalesDefinition of autismMental ageNormative sampleAutistic groupLiving skillsBehavior ScaleAutismChronological ageSocial disturbancesSkillsRelevant variablesAutisticPrecise measureMultiple regression equationMeasuresQuantitative measuresChildrenFindingsAgeDevelopment
1992
Autistic Social Dysfunction: Some Limitations of the Theory of Mind Hypothesis
Klin A, Volkmar F, Sparrow S. Autistic Social Dysfunction: Some Limitations of the Theory of Mind Hypothesis. Journal Of Child Psychology And Psychiatry 1992, 33: 861-876. PMID: 1378847, DOI: 10.1111/j.1469-7610.1992.tb01961.x.Peer-Reviewed Original ResearchConceptsTheory of mindVineland Adaptive Behavior ScalesAge of acquisitionAdaptive Behavior ScalesYoung autisticMind hypothesisSocial dysfunctionBehavior ScaleSocial behaviorDisabled childrenSocial disabilityAutismSocial developmentEarly precursorsMindItemsAutisticIQTheoryHypothesisChildrenAcquisitionDisability
1987
Social Deficits in Autism: An Operational Approach Using the Vineland Adaptive Behavior Scales
VOLKMAR F, SPARROW S, GOUDREAU D, CICCHETTI D, PAUL R, COHEN D. Social Deficits in Autism: An Operational Approach Using the Vineland Adaptive Behavior Scales. Journal Of The American Academy Of Child & Adolescent Psychiatry 1987, 26: 156-161. PMID: 3584011, DOI: 10.1097/00004583-198703000-00005.Peer-Reviewed Original ResearchConceptsVineland Adaptive Behavior ScalesSocial dysfunctionAdaptive Behavior ScalesAutistic social dysfunction
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