2025
Opportunities and Challenges in Using Electronic Health Record Systems to Study Postacute Sequelae of SARS-CoV-2 Infection: Insights From the NIH RECOVER Initiative
Mandel H, Shah S, Bailey L, Carton T, Chen Y, Esquenazi-Karonika S, Haendel M, Hornig M, Kaushal R, Oliveira C, Perlowski A, Pfaff E, Rao S, Razzaghi H, Seibert E, Thomas G, Weiner M, Thorpe L, Divers J, Cohort R. Opportunities and Challenges in Using Electronic Health Record Systems to Study Postacute Sequelae of SARS-CoV-2 Infection: Insights From the NIH RECOVER Initiative. Journal Of Medical Internet Research 2025, 27: e59217. PMID: 40053748, PMCID: PMC11923460, DOI: 10.2196/59217.Peer-Reviewed Original ResearchConceptsElectronic health recordsElectronic health record dataPostacute sequelae of SARS-CoV-2 infectionSequelae of SARS-CoV-2 infectionElectronic health record systemsHealth record systemsLong COVIDHealth recordsEHR dataEpidemiological researchRecording systemPostacute sequelaeMultifaceted conditionNational InstituteSARS-CoV-2 infectionData sourcesCOVID researchCOVIDInitiationNationalOpportunitiesDataExploring sociodemographic disparities in diagnostic problems and mistakes in the quest for diagnostic equity: insights from a national survey of patient experiences
McDonald K, Gleason K, Grob R, Yuan C, Dhingra I, Evered J, Warne E, Schlesinger M. Exploring sociodemographic disparities in diagnostic problems and mistakes in the quest for diagnostic equity: insights from a national survey of patient experiences. Frontiers In Public Health 2025, 13: 1444005. PMID: 40017549, PMCID: PMC11865055, DOI: 10.3389/fpubh.2025.1444005.Peer-Reviewed Original ResearchConceptsNational survey of patient experiencesSurvey of patient experienceU.S. population-based surveysPopulation-based surveyLower household incomeNationally Representative SampleWorking full-timePatient experienceSociodemographic disparitiesSociodemographic characteristicsSociodemographic predictorsSociodemographic groupsEpidemiological researchDiagnostic disparitiesRepresentative sampleU.S. populationHousehold incomeMultivariate regression analysisDiagnostic experienceNational surveyAnalysis of dataOutcome estimatesYounger ageCis femaleFull-timeP-271. Contact Patterns of United States Health Care Workers at Quaternary Health Center: Stability of contacts during the post-pandemic era
Pischel L, Aguolu O, Ahmed N, Campbell M, Borg R, Duckwall C, Willebrand K, Paintsil E, Muenker M, Malik A, Kiti M, Jenness S, Lopman B, Belsky J, Martinello R, Yildirim I, Ko A, Omer S. P-271. Contact Patterns of United States Health Care Workers at Quaternary Health Center: Stability of contacts during the post-pandemic era. Open Forum Infectious Diseases 2025, 12: ofae631.475. PMCID: PMC11777566, DOI: 10.1093/ofid/ofae631.475.Peer-Reviewed Original ResearchHealth care workersHealth care worker participationCare workersUnited States health care systemStates health care systemAge rangeHealth care systemHealth care workers' contactsLinear regressionHealth centersCare systemChi-square testCOVID-19 pandemic responseContact diariesEpidemiological researchParticipants' jobsWorking-age populationWorking ageConfidence intervalsImaging technologistsParticipantsPandemic responseSocial workersWork environmentWorking days
2024
US mortality trends from alcohol‐associated hepatitis by sex, age, race, and ethnicity, 1999–2020
Banini B, Chauhan S, Amatya A, Dashti F, Zahrawi K, Zahrawi F, Mehal W, McKee S. US mortality trends from alcohol‐associated hepatitis by sex, age, race, and ethnicity, 1999–2020. Alcohol Clinical And Experimental Research 2024, 49: 358-367. PMID: 39739407, DOI: 10.1111/acer.15515.Peer-Reviewed Original ResearchAmerican Indians/Alaska NativesMortality rate ratiosIndians/Alaska NativesCenters for Disease Control and Prevention Wide-ranging Online DataUS Centers for Disease Control and Prevention Wide-ranging ONline DataWide-ranging Online DataMortality rateUS mortality trendsAlcohol-associated hepatitisJoinpoint regression analysisYoung adultsCross-sectional studyAlcohol-associated liver diseaseYoung adult femalesHigh-risk populationOnline dataMortality trendsSteepest increaseUnited StatesYear compared to baselineCalendar trendsSociodemographic factorsRacial/ethnic groupsEpidemiological researchRate ratiosFour targets: an enhanced framework for guiding causal inference from observational data
Lu H, Li F, Lesko C, Fink D, Rudolph K, Harhay M, Rentsch C, Fiellin D, Gonsalves G. Four targets: an enhanced framework for guiding causal inference from observational data. International Journal Of Epidemiology 2024, 54: dyaf003. PMID: 39868475, PMCID: PMC11769716, DOI: 10.1093/ije/dyaf003.Peer-Reviewed Original ResearchThe Adult Changes in Thought (ACT) Medical Records Abstraction Project: A Resource for Research on Biological, Psychosocial and Behavioral Factors on the Aging Brain and Alzheimer’s Disease and Related Dementias
Gatto N, Renz A, Tom S, Lyons M, Macuiba J, Dodd T, Lind B, Gray S, Meyers K, Larson E, Nelson J, McEvoy L, Sankaran S, Key D, Litondo J, Crane P. The Adult Changes in Thought (ACT) Medical Records Abstraction Project: A Resource for Research on Biological, Psychosocial and Behavioral Factors on the Aging Brain and Alzheimer’s Disease and Related Dementias. Brain Sciences 2024, 14: 1075. PMID: 39595838, PMCID: PMC11592130, DOI: 10.3390/brainsci14111075.Peer-Reviewed Original ResearchAdult ChangesMembers of Kaiser Permanente WashingtonKaiser Permanente WashingtonAbstracted medical recordsMedical recordsOlder adult membersProspective cohort studyWomen's healthRelated dementiaEpidemiological researchPharmacy dataLongitudinal clinical dataCohort studyAbstracted dataMedical conditionsBehavioral factorsAlzheimer's diseasePhysical injuryDementiaParticipantsBrain autopsyBlood pressureEpidemiological investigationsPsychosocialAct dataIntegration of observational and causal evidence for the association between adiposity and 17 gastrointestinal outcomes: An umbrella review and meta‐analysis
Kim M, Lee I, Natarajan P, Do R, Kwon Y, Shin J, Solmi M, Kim J, Won H, Park S. Integration of observational and causal evidence for the association between adiposity and 17 gastrointestinal outcomes: An umbrella review and meta‐analysis. Obesity Reviews 2024, 25: e13823. PMID: 39233338, DOI: 10.1111/obr.13823.Peer-Reviewed Original ResearchConceptsBody mass indexMendelian randomizationPublic health policiesUmbrella reviewStandard deviation increaseUpper GI conditionsGI diseasesHealth policyEpidemiological researchGI conditionsSystematic reviewMass indexMeta-analysesObservational studyDeviation increaseIncreased riskMeta-analysisObesityGastrointestinal outcomesGastrointestinal (GI) diseasesIncreased AdiposityAssociationRectal cancerGallbladder diseaseFatty liver diseaseThe evolution of selection bias in the recent epidemiologic literature—a selective overview
Lu H, Howe C, Zivich P, Gonsalves G, Westreich D. The evolution of selection bias in the recent epidemiologic literature—a selective overview. American Journal Of Epidemiology 2024, 194: 580-584. PMID: 39136207, PMCID: PMC11879605, DOI: 10.1093/aje/kwae282.Peer-Reviewed Original ResearchComorbidity Profiles of Posttraumatic Stress Disorder Across the Medical Phenome
Hicks E, Niarchou M, Goleva S, Kabir D, Johnson J, Johnston K, Ciarcia J, Pathak G, Smoller J, Davis L, Nievergelt C, Koenen K, Huckins L, Choi K, Group P. Comorbidity Profiles of Posttraumatic Stress Disorder Across the Medical Phenome. Biological Psychiatry Global Open Science 2024, 4: 100337. PMID: 39050781, PMCID: PMC11268109, DOI: 10.1016/j.bpsgos.2024.100337.Peer-Reviewed Original ResearchElectronic health recordsClinical knowledge gapsPhysical health problemsPhenome-wide associationPheWAS analysisBiobank participantsHealth recordsEpidemiological researchHealthcare systemTest associationsMedical phenomeAssociated with osteoporosisPulmonary heart diseasePhecodesHealth problemsLogistic regressionPosttraumatic stress disorderSex differencesPheWASComorbidity profilesHeart diseaseStress disorderInteraction termsAssociationPTSDGeospatial Science for the Environmental Epidemiology of Cancer in the Exposome Era
VoPham T, White A, Jones R. Geospatial Science for the Environmental Epidemiology of Cancer in the Exposome Era. Cancer Epidemiology Biomarkers & Prevention 2024, 33: 451-460. PMID: 38566558, PMCID: PMC10996842, DOI: 10.1158/1055-9965.epi-23-1237.Peer-Reviewed Original ResearchConceptsEnvironmental epidemiologyExternal exposomeCancer epidemiology researchCancer screening policyEpidemiology of cancerEpidemiological studiesCancer epidemiology studiesClinical decision makingPatient addressesExposome dataEpidemiological researchScreening policyLife courseEnvironmental exposuresEnvironmental exposure assessmentOptimal practiceExposomeGeographic information systemExposure assessmentEnvironmental diseaseGeospatial scienceDecision makingGeospatial dataGeospatial methodologyCancer
2023
Assessing the Prevalence Rates of Internalizing Symptomatology Among Multiracial Adolescents in the United States: A Systematic Review
Henson-García M, Weerakoon S, Duncan C, Choe T, Opara I, A. Baker K, L. Sterling K, Messiah S. Assessing the Prevalence Rates of Internalizing Symptomatology Among Multiracial Adolescents in the United States: A Systematic Review. Child Psychiatry & Human Development 2023, 1-14. PMID: 38042957, DOI: 10.1007/s10578-023-01636-4.Peer-Reviewed Original ResearchInternalizing symptomsMultiracial adolescentsPrevalence of anxiety symptomsInternalizing symptomatologyAnxiety symptomsDepressive symptomatologySymptomatologyPrevalence estimatesMethodological inconsistenciesAdolescentsSystematic reviewSymptomsPrevalence ratesPeer-reviewed studiesAPA PsycInfoOvid MEDLINEComprehensive searchPrevalenceSTUDY SELECTIONUnited StatesEpidemiological researchAn international research agenda for clozapine-resistant schizophrenia
Luykx J, Gonzalez-Diaz J, Guu T, van der Horst M, van Dellen E, Boks M, Guloksuz S, DeLisi L, Sommer I, Cummins R, Shiers D, Lee J, Every-Palmer S, Mhalla A, Chadly Z, Chan S, Cotes R, Takahashi S, Benros M, Wagner E, Correll C, Hasan A, Siskind D, Endres D, MacCabe J, Tiihonen J. An international research agenda for clozapine-resistant schizophrenia. The Lancet Psychiatry 2023, 10: 644-652. PMID: 37329895, DOI: 10.1016/s2215-0366(23)00109-8.Peer-Reviewed Original ResearchConceptsClozapine-resistant schizophreniaQuality of lifeTreatment optionsTreatment-resistant symptomsThird of patientsNew treatment optionsHealth care providersMiddle-income countriesFunctional outcomeInterventional studyUnmet needEpidemiological researchTranslational approachDiagnostic testsPatientsSchizophreniaHealth policyEarly detectionOptionsSymptomsDiagnosisTrials
2022
Psychosocial family-level mediators in the intergenerational transmission of trauma: Protocol for a systematic review and meta-analysis
Mew E, Nyhan K, Bonumwezi J, Blas V, Gorman H, Hennein R, Quach K, Shabanova V, Hawley N, Lowe S. Psychosocial family-level mediators in the intergenerational transmission of trauma: Protocol for a systematic review and meta-analysis. PLOS ONE 2022, 17: e0276753. PMID: 36378630, PMCID: PMC9665367, DOI: 10.1371/journal.pone.0276753.Peer-Reviewed Original ResearchConceptsChild mental health outcomesSystematic review registrationRelevant study characteristicsMental health outcomesParental trauma exposureReview registrationBias assessmentRegistration IDConference abstractsPeer-reviewed publicationsPsychosocial factorsFamily-level factorsHealth outcomesSystematic reviewNarrative synthesisPsychosocial mediatorsPublication biasTrauma exposureStudy characteristicsEpidemiological researchProQuest DissertationsTraumaTrauma typesPsychological impactMediatorsSociodemographic characteristics differ across routine adult vaccine cohorts: An All of Us descriptive study
Ng D, Jia S, Wisseh C, Cadiz C, Nguyen M, Lee J, McBane S, Nguyen L, Chan A, Hurley-Kim K. Sociodemographic characteristics differ across routine adult vaccine cohorts: An All of Us descriptive study. Journal Of The American Pharmacists Association 2022, 63: 582-591.e20. PMID: 36549934, DOI: 10.1016/j.japh.2022.11.005.Peer-Reviewed Original ResearchConceptsElectronic health recordsOlder adultsUs (AoU) Research ProgramVaccinated cohortFactors associated with vaccinationPneumococcal vaccineSources of disparitiesProportion of whitesNational Institutes of HealthAoU participantsRace/ethnic disparitiesDocumenting influenza vaccinationHealth recordsHealth databasesLifestyle informationInstitutes of HealthSociodemographic characteristicsMisclassification biasHealth statusEpidemiological researchTargeted interventionsWhite participantsDescriptive statisticsHealth insuranceNon-Hispanic/Latino participants
2021
Paracetamol use during pregnancy — a call for precautionary action
Bauer AZ, Swan SH, Kriebel D, Liew Z, Taylor HS, Bornehag CG, Andrade AM, Olsen J, Jensen RH, Mitchell RT, Skakkebaek NE, Jégou B, Kristensen DM. Paracetamol use during pregnancy — a call for precautionary action. Nature Reviews Endocrinology 2021, 17: 757-766. PMID: 34556849, PMCID: PMC8580820, DOI: 10.1038/s41574-021-00553-7.Peer-Reviewed Original ResearchConceptsPregnant womenHealth professionalsBeginning of pregnancyLowest effective dosePublic health professionalsParacetamol useHigh feverModerate painSevere painPrenatal exposureUrogenital disordersConsensus statementImportant medicationsFetal developmentEffective doseEpidemiological researchPregnancyAPAPWomenMedicationsPainFeverLong-term basisFocused research effortExposureMedicine in a forgotten corner of Africa: how EMR can benefit the developing world - The FIMRC and EMR4DW experience.
Hong S, Smith P, Stewart B, Welsh M, Lee K, Shin J, Lee J. Medicine in a forgotten corner of Africa: how EMR can benefit the developing world - The FIMRC and EMR4DW experience. European Review For Medical And Pharmacological Sciences 2021, 25: 4139-4148. PMID: 34156694, DOI: 10.26355/eurrev_202106_26057.Peer-Reviewed Original ResearchConceptsElectronic medical recordsLow-resource settingsMedical recordsDisease prevalenceDisease categoriesDiseases of digestive systemQuality of lifeHealthcare providersHealth ProjectMaps of disease prevalenceEpidemiological researchCost-effective strategyBududa districtIncreased prevalence of malariaIncreased prevalenceRural African villagesStudy periodPrevalenceLimited resourcesPrevalence of malariaBududaSubcutaneous tissueDeveloping worldHealthcareDisease of skinA combination sampling approach for epidemiologic research in humanitarian settings: a case analysis of a study of depressive disorder prevalence among refugees in Greece
Poole D, Raymond N, Berens J, Latonero M, Ricard J, Hedt-Gauthier B. A combination sampling approach for epidemiologic research in humanitarian settings: a case analysis of a study of depressive disorder prevalence among refugees in Greece. BMC Public Health 2021, 21: 272. PMID: 33530961, PMCID: PMC7856792, DOI: 10.1186/s12889-021-10342-6.Peer-Reviewed Original ResearchConceptsRefugee camp settingsCamp settingBurden of depressive disordersMental health disordersDepressive disorderHumanitarian emergenciesDepressive disorder prevalenceEpidemiological researchHealth disordersStrengthening preventionHumanitarian settingsDisorder prevalencePopulation screeningRisk of coercionResearch teamSurvey studySampling approachSystematic samplingQuasi-randomizedCase analysisSyrian refugee campParticipantsResearch studiesBurdenPrevention
2020
Identifying Multisite Chronic Pain with Electronic Health Records Data
Von Korff M, DeBar LL, Deyo RA, Mayhew M, Kerns RD, Goulet JL, Brandt C. Identifying Multisite Chronic Pain with Electronic Health Records Data. Pain Medicine 2020, 21: 3387-3392. PMID: 32918481, PMCID: PMC7770230, DOI: 10.1093/pm/pnaa295.Peer-Reviewed Original ResearchConceptsMultisite chronic painElectronic health care dataChronic painChronic pain impactElectronic health recordsHealth care dataCare dataPain impactHealth recordsLong-term opioid useCommon chronic pain conditionsPain-related disabilityChronic pain conditionsKaiser Permanente NorthwestElectronic health record dataHealth record dataPositive predictive valueOpioid usePain severityPain conditionsDepressive symptomsPainPredictive valueEpidemiological researchRecord dataThe Society for Epidemiologic Research and the Future of Diversity and Inclusion in Epidemiology
Gilman S, Arah O, Bates L, Branas C, Cozier Y, Datta G, DeVilbiss E, Fink D, Hajat A, Johnson D, Lopez D, Morris M, Weuve J, Abuelezam N, Research O. The Society for Epidemiologic Research and the Future of Diversity and Inclusion in Epidemiology. American Journal Of Epidemiology 2020, 189: 1049-1052. PMID: 32602528, PMCID: PMC7666411, DOI: 10.1093/aje/kwaa109.Peer-Reviewed Original ResearchFamilial Hypercholesterolemia and the Founder Effect Among Franco-Americans: A Brief History and Call to Action
Mszar R, Buscher S, Taylor H, Rice-DeFosse M, McCann D. Familial Hypercholesterolemia and the Founder Effect Among Franco-Americans: A Brief History and Call to Action. CJC Open 2020, 2: 161-167. PMID: 32462130, PMCID: PMC7242505, DOI: 10.1016/j.cjco.2020.01.003.Peer-Reviewed Original ResearchFounder effectReduced genetic diversityFamilial hypercholesterolemiaFrench-Canadian founder populationFrench Canadian descentPremature atherosclerotic cardiovascular diseaseFrench CanadiansGenetic diversityFounder populationIncreased risk of premature atherosclerotic cardiovascular diseaseAtherosclerotic cardiovascular diseaseMontreal-FH-SCOREPopulation-based researchCardiovascular diseaseCascade screeningRisk of premature atherosclerotic cardiovascular diseaseGenetic mutationsElevated low-density lipoprotein cholesterol levelsUnited StatesProvince of QuebecTreatment gapLow-density lipoprotein cholesterol levelsEpidemiological researchOptimal lipid managementInherited disorder
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