2025
Digital Health Interventions Targeting Psychological Health in Parents of Children With Autism Spectrum Disorder: Protocol for a Scoping Review
Ji B, Batubara I, Batten J, Peng X, Chen S, Ni Z. Digital Health Interventions Targeting Psychological Health in Parents of Children With Autism Spectrum Disorder: Protocol for a Scoping Review. JMIR Research Protocols 2025, 14: e68677. PMID: 40466097, PMCID: PMC12177426, DOI: 10.2196/68677.Peer-Reviewed Original ResearchConceptsDigital health interventionsParents of childrenINTERNATIONAL REGISTERED REPORT IDENTIFIERParental psychological healthPsychological healthScoping ReviewAutism spectrum disorderDevelopment of practice guidelinesPsychological health outcomesHealth of parentsEnglish-language studiesPsychological health of parentsWeb of SciencePublic health concernHealth outcomesHealth interventionsSpectrum disorderEvidence synthesisParticipant characteristicsIntervention specificsPsychological outcomesPractice guidelinesStudy designData extractionOvid MEDLINEThe Effect of Early Warning Systems for Sepsis on Mortality: A Systematic Review and Meta-analysis
Ein Alshaeba S, Marhoffer E, Holleck J, Theisen-Toupal J, Grimshaw A, Gunderson C. The Effect of Early Warning Systems for Sepsis on Mortality: A Systematic Review and Meta-analysis. Journal Of General Internal Medicine 2025, 1-6. PMID: 40360868, DOI: 10.1007/s11606-025-09569-5.Peer-Reviewed Original ResearchStrength of evidenceLength of stayScreening groupRandomized Controlled StudyCochrane risk of bias toolRisk of bias toolRandom-effects meta-analysisLow due to riskMeta-analysisEffectiveness of screeningEffectiveness of early warning systemsRisk of biasEffects meta-analysisMethodsA systematic literature searchPooled odds ratioControlled studiesScreened adult patientsSystematic literature searchSurviving Sepsis CampaignRecommendations AssessmentCochrane riskBias toolWeb of Science Core CollectionOdds ratioOvid MEDLINEPrimary Tumors of the Brain and Central Nervous System in Adults and Children in Sub-Saharan Africa: Protocol for a Scoping Review
Al-Fikri A, Alhammadi M, Arum C, Kaur M, Del Biondo K, Bani I, Mudenda V, Vermund S. Primary Tumors of the Brain and Central Nervous System in Adults and Children in Sub-Saharan Africa: Protocol for a Scoping Review. JMIR Research Protocols 2025, 14: e66978. PMID: 40273436, PMCID: PMC12062764, DOI: 10.2196/66978.Peer-Reviewed Original ResearchConceptsINTERNATIONAL REGISTERED REPORT IDENTIFIERInternational Agency for Research on CancerSub-Saharan AfricaScoping ReviewIndependent reviewersIncidence rateCentral nervous systemFull-text screeningLow-resource settingsCentral nervous system cancerSub-SaharanNeurosurgery facilityPRISMA-ScRLow incidence rateGlobal health organizationsEvidence synthesisService gapsReviewed titlesGrey literaturePRISMA-PAbstract screeningTreatment of CNS tumorsCentral nervous system tumorsOvid MEDLINEEligibility criteriaPredictors and Uptake of Lung Cancer Screening in the US: An Integrative Literature Review
Sarkar S, Choa E, Manzo L, Richman I, Batten J, Raziani Y, Poghosyan H. Predictors and Uptake of Lung Cancer Screening in the US: An Integrative Literature Review. Lung Cancer 2025, 203: 108529. PMID: 40253942, DOI: 10.1016/j.lungcan.2025.108529.Peer-Reviewed Original ResearchConceptsLung cancer screeningCancer screeningUptake of lung cancer screeningLung cancer screening utilizationLung cancer mortalityOrganizational-level policiesIntegrative literature reviewUS-based studiesCancer mortalityUninsured individualsDecision-making resourcesOvid MEDLINEInclusion criteriaOvid EmbaseMedical librariansExclusion criteriaDisparitiesOvidEarly detectionLiterature reviewCINAHLScreeningLung cancerMEDLINEEMBASETransparency in United States healthcare sustainability: a scoping review
Locke S, Hadley C, Sherman J, Hantel A, Senay E. Transparency in United States healthcare sustainability: a scoping review. Environmental Research Health 2025, 3: 022001. DOI: 10.1088/2752-5309/adb06d.Peer-Reviewed Original ResearchHealthcare sustainabilitySustainability initiativesEnvironmental sustainability practicesNon-peer-reviewed literatureHealth care administratorsBusiness of healthcareCorporate reportingPublic health impactIntegrate sustainabilitySustainable practicesScoping ReviewCare administratorsHealthcare literatureSustainability dataU.S. healthcareThematic analysisIndependent reviewersOvid MEDLINEHealthcareInclusion criteriaGreenwashingTransparent reportingBody of researchHealth impactsGrowing body of researchImpact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis
Sumsuzzman D, Ye Y, Wang Z, Pandey A, Langley J, Galvani A, Moghadas S. Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis. BMC Infectious Diseases 2025, 25: 215. PMID: 39948450, PMCID: PMC11827239, DOI: 10.1186/s12879-025-10610-5.Peer-Reviewed Original ResearchConceptsPopulation settingEffective public health strategiesConfidence intervalsImpact of disease severityModified Newcastle-Ottawa ScalePublic health strategiesHigher secondary attack rateRisk of biasNewcastle-Ottawa ScalePandemic responseGlobal systematic reviewRandom-effects modelFreeman-Tukey double arcsine transformationWeb of ScienceNo significant associationDrivers of SARS-CoV-2 transmissionHealth strategiesSecondary attack rateSARS-CoV-2Disease severityEffective pandemic responseTargeted interventionsDouble arcsine transformationOvid MEDLINESystematic reviewA systematic review on the assessment of pregnancy-specific psychological trauma during pregnancy: A call to action
Givrad S, Wall K, Goldman L, Shin J, Novak E, Lowell A, Penner F, Day M, Papa L, Wright D, Rutherford H. A systematic review on the assessment of pregnancy-specific psychological trauma during pregnancy: A call to action. AJOG Global Reports 2025, 5: 100451. PMID: 40093874, PMCID: PMC11909425, DOI: 10.1016/j.xagr.2025.100451.Peer-Reviewed Original ResearchSystematic reviewPerinatal periodPsychological traumaPreferred Reporting ItemsCare deliveryWeb of ScienceReporting ItemsHealthcare systemIndependent reviewersInfant healthSecondary analysisScreening measuresOvid MEDLINEFull-textOvid EmbaseHistory of traumatic experiencesResearch teamPsychological disordersPerinatal individualsOvidPregnancyTraumatic experiencesTeamTraumaPsycINFOClinical features and endoscopic management of sharp wooden object ingestions: a systematic review of 479 cases
Chen K, Chipkin B, Grimshaw A, Bazerbachi F, Li D. Clinical features and endoscopic management of sharp wooden object ingestions: a systematic review of 479 cases. Gastroenterology Report 2025, 13: goaf035. PMID: 40364971, PMCID: PMC12073997, DOI: 10.1093/gastro/goaf035.Peer-Reviewed Original ResearchAdverse eventsClinical presentationEndoscopic removalIncreased risk of adverse eventsRisk factorsRisk of adverse eventsGastrointestinal tractSystematic reviewAbdominal painClinical featuresEndoscopic managementImaging findingsMale sexComputed tomographyCommon symptomsClinical algorithmIncreased riskCochrane LibraryCases of adultsMortality rateOvid MEDLINEPatientsForeign bodyOvid EmbaseGoogle ScholarGlobal variation in the assessment of psychological trauma in pregnancy
Wall K, Penner F, Goldman L, Shin J, Novak E, Lowell A, Day M, Papa L, Wright D, Givrad S, Rutherford H. Global variation in the assessment of psychological trauma in pregnancy. Cambridge Prisms Global Mental Health 2025, 12: e10. PMID: 39935728, PMCID: PMC11810758, DOI: 10.1017/gmh.2024.152.Peer-Reviewed Original ResearchSub-Saharan AfricaPregnant peopleSystematic reviewPsychological traumaImpact health outcomesMiddle EastIn-house assessmentPrevalence of traumatic experiencesCulturally appropriate measuresPreferred Reporting ItemsTraumatic experiencesObstetric careWeb of ScienceHealth outcomesCentral AmericaReporting ItemsSecondary analysisOvid MEDLINESub-SaharanOvid EmbaseSystematic literature reviewGeopolitical regionsAssessment of psychological traumaAfricaInterpersonal trauma
2024
Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysis
Rassi A, Grimshaw A, Sarwal A, Sah R, Shah S, Agudelo Higuita N, Rassi F, Corbisiero M, Kyllo H, Stellern J, Kaplan S, Marcos L, Ramírez-García E, Casapia M, Hotez P, Bottazzi M, Patel S, Franco-Paredes C, Marin-Neto J, Henao-Martínez A. Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysis. EClinicalMedicine 2024, 79: 102972. PMID: 39810938, PMCID: PMC11732499, DOI: 10.1016/j.eclinm.2024.102972.Peer-Reviewed Original ResearchChronic Chagas diseaseMethodological quality of studiesCardiovascular deathQuality of studiesDisease progressionQuality of evidenceVirtual Health Library databasesRisk of bias scaleCardiovascular outcomesRandom-effects modelPooled risk ratioMeta-analysis of studiesMethodological qualityWeb of Science Core CollectionAntitrypanosomal therapyRandomized Controlled StudyManagement of Chagas diseaseOvid MEDLINESystematic reviewInclusion criteriaMeta-analysesRisk ratioScience Core CollectionPrimary outcomeOvid EmbasePotential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review
Jalilian-Khave L, Kitaneh R, Ysrayl B, Borelli A, Funaro M, Potenza M, Angarita G. Potential roles for vitamin D in preventing and treating impulse control disorders, behavioral addictions, and substance use disorders: A scoping review. Addiction Neuroscience 2024, 14: 100190. PMID: 40083958, PMCID: PMC11902922, DOI: 10.1016/j.addicn.2024.100190.Peer-Reviewed Original ResearchImpulse control disordersSubstance use disordersControl disordersBehavioral addictionsTreating impulse control disordersVitamin DClinical studiesAddictive disordersSerotonergic circuitsExposure to vitamin DVitamin D deficiencyVitamin D levelsSymptom presenceDisordersPotential beneficial effectsJoanna Briggs InstituteD deficiencyPotential therapeutic mechanismAddictionD levelsWeb of ScienceTherapeutic mechanismQuality of studiesCochrane LibraryOvid MEDLINE12426 Performance Of Dehydroepiandrosterone-Sulphate In Diagnosing Mild Autonomous Cortisol Secretion: A Systematic Review And Meta-Analysis
Saini J, Salama B, Chacko S, Yu K, Bancos I. 12426 Performance Of Dehydroepiandrosterone-Sulphate In Diagnosing Mild Autonomous Cortisol Secretion: A Systematic Review And Meta-Analysis. Journal Of The Endocrine Society 2024, 8: bvae163.256. PMCID: PMC11454422, DOI: 10.1210/jendso/bvae163.256.Peer-Reviewed Original ResearchMild autonomous cortisol secretionRisk of biasMeta-analysisAutonomous cortisol secretionSystematic reviewDehydroepiandrosterone sulfateReference groupRandom-effects meta-analysisEffects meta-analysisOvid Cochrane Central Register of Controlled TrialsNon-Indexed CitationsCochrane Central Register of Controlled TrialsCentral Register of Controlled TrialsMeta-analysis of published literatureRegister of Controlled TrialsDiagnostic accuracy studiesMeta-analysis of studiesDiagnostic accuracy estimatesMeasurement of dehydroepiandrosterone sulfateDatabase inceptionCortisol secretionBaseline dehydroepiandrosterone sulfateMeasured dehydroepiandrosterone sulfateOvid MEDLINEReference standardFirst-Generation Low-Income Individuals in Medicine: A Scoping Review
Zheng S, Brutus N, Rivera A, O’Marr J, Gardezi M, Grimshaw A, Malcolm K, Marcellon R, Mason H, Cavallo J. First-Generation Low-Income Individuals in Medicine: A Scoping Review. Academic Medicine 2024, 100: 507-521. PMID: 39292871, PMCID: PMC11910383, DOI: 10.1097/acm.0000000000005877.Peer-Reviewed Original ResearchLow-income individualsLevel of evidenceScoping ReviewMedical schoolsFamily medicine specialtyMedical education stakeholdersComprehensive scoping reviewHighest level of evidenceU.S. medical schoolsDatabase searchEnglish-language articlesPrimary careLeaves of absenceUnderserved communitiesMedicine specialtyMedical school performanceWeb of Science Core CollectionDatabase inceptionLow-incomeMedical educationData extractionOvid MEDLINEEvidence levelRisk adjustmentScience Core CollectionLong-Term Use of Muscle Relaxant Medications for Chronic Pain
Oldfield B, Gleeson B, Morford K, Adams Z, Funaro M, Becker W, Merlin J. Long-Term Use of Muscle Relaxant Medications for Chronic Pain. JAMA Network Open 2024, 7: e2434835. PMID: 39298168, PMCID: PMC11413720, DOI: 10.1001/jamanetworkopen.2024.34835.Peer-Reviewed Original ResearchConceptsLow back painBack painSkeletal muscle relaxantsChronic painRandomized clinical trialsNeck painCohort studyEfficacy of long-term useLong-term useSystematically searched Ovid MEDLINEMuscle relaxant medicationsModerate risk of biasOpioid prescribing guidelinesRisk of biasQuality of cohort studiesWeb of SciencePainful crampsRelaxant medicationsChronic pain syndromesPainful spasmsOvid MEDLINEPrescribing guidelinesSystematic reviewIncreased prescriptionModerate riskSystematic review: The use of large language models as medical chatbots in digestive diseases
Giuffrè M, Kresevic S, You K, Dupont J, Huebner J, Grimshaw A, Shung D. Systematic review: The use of large language models as medical chatbots in digestive diseases. Alimentary Pharmacology & Therapeutics 2024, 60: 144-166. PMID: 38798194, DOI: 10.1111/apt.18058.Peer-Reviewed Original ResearchLanguage modelAdverse patient safety eventsPatient safety eventsClinical decision supportRisk of biasSystematic literature searchWeb of Science Core CollectionCombination of keywordsMedical chatbotTriage recommendationsHealthcare systemScience Core CollectionNecessary careSafety eventsOverburden healthcare systemsMedical adviceOvid MEDLINEMultiple specialtiesDecision supportOvid EmbaseCochrane LibrarySingle-study resultsGoogle ScholarLiterature searchGastroenterologyDisparities in race, ethnicity, sex, and age inclusion in pancreatic cancer screening studies: a systematic review and meta-analysis
Silva-Santisteban A, Hernandez Woodbine M, Noriega M, Rabinowitz L, Grimshaw A, Farrell J, Chhoda A, Sawhney M. Disparities in race, ethnicity, sex, and age inclusion in pancreatic cancer screening studies: a systematic review and meta-analysis. Gastrointestinal Endoscopy 2024, 100: 1-16.e20. PMID: 38432492, DOI: 10.1016/j.gie.2024.02.014.Peer-Reviewed Original ResearchCancer screening studyPopulation-based benchmarksPancreatic cancer screeningProportion of study participantsScreening studiesPancreatic cancer outcomesAge reportingInclusion of participantsMedian participant ageCancer screeningCancer outcomesStudy qualityWeb of Science Core CollectionNon-LatinoStudy participantsParticipant agePancreatic cancer studiesYear of publicationOvid MEDLINEGeneral populationSystematic reviewMeta-RegressionSystematic searchScience Core CollectionOvid EmbaseOn the proportion of patients who experience a prodrome prior to psychosis onset: A systematic review and meta-analysis
Benrimoh D, Dlugunovych V, Wright A, Phalen P, Funaro M, Ferrara M, Powers A, Woods S, Guloksuz S, Yung A, Srihari V, Shah J. On the proportion of patients who experience a prodrome prior to psychosis onset: A systematic review and meta-analysis. Molecular Psychiatry 2024, 29: 1361-1381. PMID: 38302562, DOI: 10.1038/s41380-024-02415-w.Peer-Reviewed Original ResearchSources of heterogeneitySystematic reviewProportion of patientsMeta-analysisSubgroup analysisCochrane Database of Systematic ReviewsDatabase of Systematic ReviewsMeta-analysis of studies of patientsPsychosis onsetProspective cohort studyCochrane Central Register of Controlled TrialsCentral Register of Controlled TrialsRegister of Controlled TrialsAPA PsycInfoNarrative synthesisMeta-analysis estimatesCochrane Central RegisterPrevention of psychosisAscertainment methodsWeb of Science Core CollectionRecall biasQualitative studyAssess heterogeneityCohort studyOvid MEDLINETreatment of critical bleeding events in patients with immune thrombocytopenia: a protocol for a systematic review and meta-analysis
Sirotich E, Nazaryan H, Chowdhury S, Guyatt G, Agarwal A, Leong R, Wen A, Xu E, Liu B, Pallapothu S, Rathod P, Kwon H, Dookie J, Shafiee A, Charness J, DiRaimo J, Paynter D, Pruitt B, Strachan G, Couban R, Ye Z, Arnold D. Treatment of critical bleeding events in patients with immune thrombocytopenia: a protocol for a systematic review and meta-analysis. Systematic Reviews 2024, 13: 21. PMID: 38184622, PMCID: PMC10770981, DOI: 10.1186/s13643-023-02436-6.Peer-Reviewed Original ResearchConceptsCritical bleedingSystematic reviewEvidence-based treatment protocolsBleeding-related mortalityCochrane Central RegisterEvidence-based recommendationsFull-text screeningBleeding eventsImmune thrombocytopeniaRecommendations AssessmentCentral RegisterControlled TrialsPrimary outcomeSevere thrombocytopeniaPlatelet countEligible studiesPatient outcomesEmergency settingOvid MEDLINEObservational studyTreatment protocolHigh riskMedical emergencyElectronic databasesMethodsLiterature searchEfficacy of Antibody Drug Conjugates Alone and in Combination with other Agents in Metastatic Urothelial Carcinoma: A Scoping Review
Grant M, Stockhammer P, Austin M, Nemeth Z, Petrylak D. Efficacy of Antibody Drug Conjugates Alone and in Combination with other Agents in Metastatic Urothelial Carcinoma: A Scoping Review. Bladder Cancer 2024, 10: 9-23. PMID: 38993528, PMCID: PMC11181835, DOI: 10.3233/blc-230070.Peer-Reviewed Original ResearchMetastatic urothelial carcinomaAntibody-drug conjugatesClinical trialsUrothelial carcinomaCombination regimensDrug conjugatesSystematic reviewAnti-PD-1 agentsProspective therapeutic clinical trialsCochrane Central TrialsClinical trial cohortObjective response rateTherapeutic clinical trialsMeta-Analyses (PRISMA) statementNon-duplicated articlesPreferred Reporting ItemsComprehensive systematic reviewPotent cytotoxic payloadTrial cohortEnfortumab vedotinOvid EmbaseSacituzumab govitecanADC targetImpressive efficacyOvid MEDLINEExploring Facilitators and Barriers to STD/STI/HIV Self-Testing Among College Students in the United States: A Scoping Review
Reeves J, Zigah E, Shamrock O, Khan D, Batten J, Abu-Ba’are G, Nelson L, Djiadeu P. Exploring Facilitators and Barriers to STD/STI/HIV Self-Testing Among College Students in the United States: A Scoping Review. Journal Of Primary Care & Community Health 2024, 15: 21501319241291758. PMID: 39439284, PMCID: PMC11497516, DOI: 10.1177/21501319241291758.Peer-Reviewed Original ResearchConceptsAvailability of healthcareSelf-test kitsRisk of STIsSelf-testingEnglish-language studiesYoung adult college studentsDiminish stigmaScoping ReviewHealth policyWeb of Science Core CollectionTesting ratesCollege studentsRemoving duplicatesOvid MEDLINEGeneral populationCochrane CENTRALScience Core CollectionOvid EmbaseAdult college studentsExclusion criteriaSexual practicesU.S. ResultsInclusion requirementsDatabase searchOvid
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