2024
Relationship between neuroimaging and cognition in frontotemporal dementia: An FDG‐PET and structural MRI study
Cayir S, Volpi T, Toyonaga T, Gallezot J, Yang Y, Sadabad F, Mulnix T, Mecca A, Fesharaki‐Zadeh A, Matuskey D. Relationship between neuroimaging and cognition in frontotemporal dementia: An FDG‐PET and structural MRI study. Journal Of Neuroimaging 2024, 34: 627-634. PMID: 38676301, PMCID: PMC11511789, DOI: 10.1111/jon.13206.Peer-Reviewed Original ResearchMoCA scoresFDG-PETAssociation of cognitionStandardized uptake value ratioMontreal Cognitive AssessmentSignificant positive associationFrontotemporal dementiaPrimary outcome measurePosterior cingulate cortexDecline of cognitive functionYears of ageGM volumeFrontal cortexOutcome measuresCognitive dysfunctionGray matterCognitive AssessmentMoCAAssociated with cognitive dysfunctionFluorodeoxyglucose (FDG)-PETPositive associationMagnetic resonance imagingPartial volume correctionCognitive functionDementia
2023
The mortality burden of extreme heat in Connecticut: A time series analysis
Goddard E, Lin C, Ma Y, Chen K. The mortality burden of extreme heat in Connecticut: A time series analysis. PLOS Climate 2023, 2: e0000164. DOI: 10.1371/journal.pclm.0000164.Peer-Reviewed Original ResearchMortality burdenGlobal Burden of Disease 2019 studyClimate changeHealth impact estimatesStatistically significant positive associationTemperature percentileQuasi-Poisson regressionSignificant positive associationAll-Cause MortalityNegative health effectsTime series analysisLong-term trendsGlobal burdenHeat-related mortalityRelative riskEpidemiological evidenceGeneralized linear modelClimate change planningSeasonal deathsHealth impactsPublic healthPositive associationRegional policy decisionsWarm seasonHealthShort-Term Association between Sulfur Dioxide and Mortality: A Multicountry Analysis in 399 Cities
O’Brien E, Masselot P, Sera F, Roye D, Breitner S, Ng C, de Sousa Zanotti Stagliorio Coelho M, Madureira J, Tobias A, Vicedo-Cabrera A, Bell M, Lavigne E, Kan H, Gasparrini A, Network M. Short-Term Association between Sulfur Dioxide and Mortality: A Multicountry Analysis in 399 Cities. Environmental Health Perspectives 2023, 131: 037002. PMID: 36883823, PMCID: PMC9994178, DOI: 10.1289/ehp11112.Peer-Reviewed Original ResearchConceptsExposure-response relationshipRelative riskShort-term associationsShort-term exposureRR of mortalitySteeper exposure-response relationshipsBi-pollutant modelsIndependent mortality riskSubstantial excess mortalityWorld Health Organization (WHO) guideline limitsSignificant positive associationEpidemiological evidenceExcess mortalityMortality riskAdvanced study designsExcess deathsMortality fractionsSecondary analysisStudy designMortalityStudy periodExposure levelsPotential roleDaily concentrationsDaily mortality
2022
Examining the effects of age and sex on tau PET binding in the absence of beta‐amyloid pathology
Gordon B, Flores S, Dincer A, Keefe S, McKay N, Hobbs D, Wisch J, Hornbeck R, Franklin E, Jack C, Koeppe R, Xiong C, McDade E, van Dyck C, Klein G, Pariente J, Bateman R, Morris J, Perrin R, Benzinger T. Examining the effects of age and sex on tau PET binding in the absence of beta‐amyloid pathology. Alzheimer's & Dementia 2022, 18 DOI: 10.1002/alz.063285.Peer-Reviewed Original ResearchPrimary age-related tauopathyTau-PET bindingTau-PETTemporal gyrusPET bindingBeta-amyloid pathologyAge-related tauopathyRostral middle frontal gyrusSubthreshold levelsElevated tracer uptakeTau PET imagingTau bindingInferior temporal gyrusInferior temporal cortexMiddle frontal gyrusSuperior temporal gyrusEffect of ageAlzheimer pathologyAmyloid pathologySignificant positive associationLateral parietalTemporal cortexTracer uptakeAlzheimer's diseaseSecondary analysisExamining the effects of sex and age on tau PET binding in the absence of beta‐amyloid pathology
Gordon B, Flores S, Dincer A, Keefe S, McKay N, Hobbs D, Wisch J, Hornbeck R, Franklin E, Jack C, Koeppe R, Xiong C, van Dyck C, McDade E, Klein G, Pariente J, Bateman R, Morris J, Ances B, Benzinger T, Perrin R. Examining the effects of sex and age on tau PET binding in the absence of beta‐amyloid pathology. Alzheimer's & Dementia 2022, 18 DOI: 10.1002/alz.061090.Peer-Reviewed Original ResearchPrimary age-related tauopathyTau-PET bindingTau-PETTemporal gyrusPET bindingBeta-amyloid pathologyAge-related tauopathyRostral middle frontal gyrusElevated tracer uptakeSub-threshold levelsTau PET imagingTau bindingInferior temporal gyrusInferior temporal cortexMiddle frontal gyrusSuperior temporal gyrusAlzheimer pathologyAmyloid pathologySignificant positive associationSynaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11C]UCB‐J
Mecca AP, O'Dell RS, Sharp ES, Banks ER, Bartlett HH, Zhao W, Lipior S, Diepenbrock NG, Chen M, Naganawa M, Toyonaga T, Nabulsi NB, Vander Wyk B, Arnsten AFT, Huang Y, Carson RE, van Dyck C. Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [11C]UCB‐J. Alzheimer's & Dementia 2022, 18: 2527-2536. PMID: 35174954, PMCID: PMC9381645, DOI: 10.1002/alz.12582.Peer-Reviewed Original ResearchConceptsSynaptic densityEarly Alzheimer's diseaseAlzheimer's diseaseCognitive performanceMajor pathological correlateGray matter volumePositron emission tomography (PET) imagingEmission Tomography ImagingPET imaging studiesIndividual cognitive domainsNeuropathologic studiesSignificant positive associationSynapse lossSynaptic alterationsPathological correlatesNeuropsychological test performanceMatter volumeCognitive impairmentSignificant associationImaging studiesDiseaseTomography imagingGlobal cognitionStrongest predictorPositive associationDepression and alcohol use in American Indian adolescents: The influence of family factors
Schick M, Nalven T, Thomas E, Weiss N, Spillane N. Depression and alcohol use in American Indian adolescents: The influence of family factors. Alcohol Clinical And Experimental Research 2022, 46: 141-151. PMID: 35076972, PMCID: PMC8988920, DOI: 10.1111/acer.14748.Peer-Reviewed Original ResearchConceptsCo-occurrence of depressionDepressive symptomsAlcohol useFamily factorsFamily warmthGreater depressive symptomsStatistically significant positive associationCulturally sensitive preventionNationally Representative SampleAI adolescentsInfluence of family factorsSignificant positive associationParental monitoringGreater alcohol useRepresentative sampleSensitive preventionTreatment approachesAlcohol misuseGeneral populationLevels of parental monitoringAmerican Indian adolescentsPositive associationSymptomsDepressionIndian adolescents
2021
Avoidance in Adolescence: The Balloon Risk Avoidance Task (BRAT)
Crowley M, van Noordt S, Castagna P, Vaca F, Wu J, Lejuez C, Mayes L. Avoidance in Adolescence: The Balloon Risk Avoidance Task (BRAT). Journal Of Psychopathology And Behavioral Assessment 2021, 44: 297-311. DOI: 10.1007/s10862-021-09928-6.Peer-Reviewed Original ResearchBalloon Analogue Risk TaskAvoidance behaviorRisk TaskMore avoidance behaviorSubset of youthRisk-taking behaviorMotivational correlatesBehavioral measuresAnxiety symptomsAvoidance taskLate adolescenceDiscriminant validityValidity dataDepressed moodAdolescenceAge 10TaskYouthAvoidanceAnxietyGreater levelsSignificant positive associationClinical implicationsPositive associationLess attentionThe Patient Care Ownership Scale: External Validation of an Instrument that Measures Patient Care Ownership Among Internal Medicine Trainees—a Multi-Institutional Study
Djulbegovic M, Kulkarni SA, Chen KL, Canavan M, White MA, McGuire WC, Shan S, Reddy R, Kay S, Fraenkel L. The Patient Care Ownership Scale: External Validation of an Instrument that Measures Patient Care Ownership Among Internal Medicine Trainees—a Multi-Institutional Study. Journal Of General Internal Medicine 2021, 36: 3680-3688. PMID: 33782886, PMCID: PMC8642535, DOI: 10.1007/s11606-021-06703-x.Peer-Reviewed Original ResearchConceptsItem reductionIntensive care unitMedicine residentsCross-sectional studyMulti-institutional studyPARTICIPANTSInternal medicine residentsPositive associationInternal medicine traineesOwnership scaleInternal medicine residentsCare unitSignificant positive associationMain MeasuresWeKey ResultsOfPatient care ownershipEligible residentsPatient careSignificant associationBivariate analysisInpatient rotationsResident physiciansMedicine traineesCronbach's αExternal validationDecision ownershipAssessment of Comorbid Depression and Anxiety in Inflammatory Bowel Disease Using Adaptive Testing Technology
Karpin J, Rodriguez T, Traboulsi C, Rai V, Gibbons R, Rubin D. Assessment of Comorbid Depression and Anxiety in Inflammatory Bowel Disease Using Adaptive Testing Technology. Crohn's & Colitis 360 2021, 3: otaa095. PMID: 34746788, PMCID: PMC8570563, DOI: 10.1093/crocol/otaa095.Peer-Reviewed Original ResearchInflammatory bowel diseaseBowel diseaseExact testActive inflammatory bowel diseaseClinical remission statusNegative CRP valuesMental health screeningPearson's chi-square testFisher's exact testMental health conditionsChi-square testCAT-MHIBD clinicIBD patientsPositive CRPUndiagnosed anxietyClinical remissionDisease activityIBD populationPatient characteristicsConsecutive patientsCRP valuesMultivariable analysisSignificant positive associationRemission status
2020
Association of maternal depression and home adversities with infant hypothalamic-pituitary-adrenal (HPA) axis biomarkers in rural Pakistan
Hagaman AK, Baranov V, Chung E, LeMasters K, Andrabi N, Bates LM, Rahman A, Sikander S, Turner E, Maselko J. Association of maternal depression and home adversities with infant hypothalamic-pituitary-adrenal (HPA) axis biomarkers in rural Pakistan. Journal Of Affective Disorders 2020, 276: 592-599. PMID: 32871690, PMCID: PMC7792907, DOI: 10.1016/j.jad.2020.07.053.Peer-Reviewed Original ResearchConceptsHPA axis activityMaternal depressionSocio-economic statusYear postpartumDHEAS levelsAxis activityIntimate partner violenceInfant stress response systemsSignificant associationLow DHEAS levelsHPA axis dysregulationHPA axis hormonesOne-year-old infantsYears of ageConsistent significant associationsChildren's HPA-axis activityHigher socio-economic statusSignificant positive associationAxis dysregulationAxis hormonesAdrenal axisStress-related diseasesDHEA activityInfant cortisolDepression severitySurgery Task Load Index in Cardiac Surgery: Measuring Cognitive Load Among Teams
Kennedy-Metz L, Wolfe H, Dias R, Yule S, Zenati M. Surgery Task Load Index in Cardiac Surgery: Measuring Cognitive Load Among Teams. Surgical Innovation 2020, 27: 602-607. PMID: 32938323, PMCID: PMC7744397, DOI: 10.1177/1553350620934931.Peer-Reviewed Original ResearchConceptsTask Load IndexCognitive loadSurgery Task Load IndexNASA Task Load IndexTeam measuresLoad indexCorrelational analysisTemporal sensitivityTeam membersSURG-TLXIndividual measuresSignificant positive associationPositive associationMeasuresSubjective assessmentSurgery team membersTeamLow levelsRelationshipIndividualsGeneral populationFindings
2016
Stress hormones and posttraumatic stress symptoms following paediatric critical illness: an exploratory study
Als LC, Picouto MD, O’Donnell K, Nadel S, Cooper M, Pierce CM, Kramer T, Glover VAS, Garralda ME. Stress hormones and posttraumatic stress symptoms following paediatric critical illness: an exploratory study. European Child & Adolescent Psychiatry 2016, 26: 511-519. PMID: 27995329, PMCID: PMC5394132, DOI: 10.1007/s00787-016-0933-3.Peer-Reviewed Original ResearchConceptsPediatric critical illnessPosttraumatic stress symptomsCritical illnessHealthy controlsEvening cortisolCortisol concentrationsExploratory case-control studyStress symptomsModest independent predictorCase-control studyEvening cortisol concentrationsBasal cortisol concentrationsPICU admissionPICU groupIndependent predictorsSeptic illnessSymptoms of PTSDSignificant positive associationStudy of childrenPrimary analysisMultivariate analysisSecondary analysisCortisol regulationConsecutive weekdaysStress hormonesIntimate Partner Violence and HIV-Risk Behaviors: Evaluating Avoidant Coping as a Moderator
Weiss NH, Peasant C, Sullivan TP. Intimate Partner Violence and HIV-Risk Behaviors: Evaluating Avoidant Coping as a Moderator. AIDS And Behavior 2016, 21: 2233-2242. PMID: 27778220, PMCID: PMC5472532, DOI: 10.1007/s10461-016-1588-2.Peer-Reviewed Original ResearchChronic Recreational Physical Inactivity and Epithelial Ovarian Cancer Risk: Evidence from the Ovarian Cancer Association Consortium
Cannioto R, LaMonte MJ, Risch HA, Hong CC, Sucheston-Campbell LE, Eng KH, Szender JB, Chang-Claude J, Schmalfeldt B, Klapdor R, Gower E, Minlikeeva AN, Zirpoli GR, Bandera EV, Berchuck A, Cramer D, Doherty JA, Edwards RP, Fridley BL, Goode EL, Goodman MT, Hogdall E, Hosono S, Jensen A, Jordan S, Group O, Kjaer S, Matsuo K, Ness R, Olsen C, Olson S, Pearce C, Pike M, Rossing M, Szamreta E, Thompson P, Tseng C, Vierkant R, Webb P, Wentzensen N, Wicklund K, Winham S, Wu A, Modugno F, Schildkraut J, Terry K, Kelemen L, Moysich K. Chronic Recreational Physical Inactivity and Epithelial Ovarian Cancer Risk: Evidence from the Ovarian Cancer Association Consortium. Cancer Epidemiology Biomarkers & Prevention 2016, 25: 1114-1124. PMID: 27197285, PMCID: PMC4930728, DOI: 10.1158/1055-9965.epi-15-1330.Peer-Reviewed Original ResearchConceptsRecreational physical inactivityRecreational physical activityPhysical inactivityEOC riskPooled analysisPhysical activityWeekly recreational physical activityLarge pooled analysisIndependent risk factorEpithelial ovarian cancer riskPhysical activity guidelinesBody mass indexMultivariable logistic regressionConfidence intervalsOvarian cancer riskOvarian Cancer Association ConsortiumDose of activityMenopausal statusChronic inactivityActivity guidelinesEOC patientsMass indexSignificant positive associationBody of evidenceIndependent association
2015
Systematic Review and Meta-Analysis: Dose-Response Relationship of Selective Serotonin Reuptake Inhibitors in Major Depressive Disorder
Jakubovski E, Varigonda AL, Freemantle N, Taylor MJ, Bloch MH. Systematic Review and Meta-Analysis: Dose-Response Relationship of Selective Serotonin Reuptake Inhibitors in Major Depressive Disorder. American Journal Of Psychiatry 2015, 173: 174-183. PMID: 26552940, PMCID: PMC4975858, DOI: 10.1176/appi.ajp.2015.15030331.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsMajor depressive disorderSerotonin reuptake inhibitorsDepressive disorderHigh dosesTreatment responseReuptake inhibitorsBenefit of SSRIsEfficacy of SSRIsTolerability of SSRIsEffects of SSRIsRandomized placebo-controlled trialPlacebo-controlled trialStratified subgroup analysisTherapeutic dose rangeDose-response relationshipSSRI doseTolerability analysisMedication dosesSignificant positive associationSubgroup analysisMultiple time pointsDose categoriesMixed regression modelsCause dropoutsAmbient air pollution and congenital heart defects in Lanzhou, China
Jin L, Qiu J, Zhang Y, Qiu W, He X, Wang Y, Sun Q, Li M, Zhao N, Cui H, Liu S, Tang Z, Chen Y, Yue L, Da Z, Xu X, Huang H, Liu Q, Bell ML, Zhang Y. Ambient air pollution and congenital heart defects in Lanzhou, China. Environmental Research Letters 2015, 10: 074005. PMID: 31555342, PMCID: PMC6760856, DOI: 10.1088/1748-9326/10/7/074005.Peer-Reviewed Original ResearchPatent ductus arteriosusEntire pregnancyCongenital heart defectsMaternal exposureCongenital malformationsHeart defectsCongenital heartFolic acid intakeSingleton live birthsTherapeutic drug usePositive associationAmbient air pollutionDuctus arteriosusSeason of conceptionGreat arteriesSignificant positive associationAcid intakeMaternal ageHealth burdenLive birthsCardiac septumTrimesterDrug usePregnancyLogistic regressionGreater perceived ability to form vivid mental images in individuals with high compared to low BMI
Patel BP, Aschenbrenner K, Shamah D, Small DM. Greater perceived ability to form vivid mental images in individuals with high compared to low BMI. Appetite 2015, 91: 185-189. PMID: 25865661, DOI: 10.1016/j.appet.2015.04.005.Peer-Reviewed Original ResearchConceptsImagery abilityMental imagery abilityFrequent food cravingsFood cue reactivityVivid mental imagesHierarchical regression analysisMental imageryOlfactory imageryCue reactivityVisual objectsMental imagesFood cravingsPositive associationSecond experimentSignificant positive associationBest predictorParticipantsIndividualsAbilityImageryCravingObese individualsMeasuresRegression analysisCorrelation analysis
2014
Food cravings, food intake, and weight status in a community-based sample
Chao A, Grilo CM, White MA, Sinha R. Food cravings, food intake, and weight status in a community-based sample. Eating Behaviors 2014, 15: 478-482. PMID: 25064302, PMCID: PMC4115250, DOI: 10.1016/j.eatbeh.2014.06.003.Peer-Reviewed Original ResearchConceptsFood frequency questionnaireFood Craving InventoryFood cravingsHabitual intakeFood intakeSemi-quantitative food frequency questionnaireFast-food fatsCommunity-based sampleCarbohydrates/starchesFrequency questionnaireSignificant positive associationWeight statusBMIHigh fatIntakeComprehensive assessment batteryCravingType of foodAssessment BatteryRespective intakesPositive associationSignificant interactionFatAssociationFoodThe underlying role of posttraumatic stress disorder symptoms in the association between intimate partner violence and deliberate self-harm among African American women
Weiss NH, Dixon-Gordon KL, Duke AA, Sullivan TP. The underlying role of posttraumatic stress disorder symptoms in the association between intimate partner violence and deliberate self-harm among African American women. Comprehensive Psychiatry 2014, 59: 8-16. PMID: 25752736, PMCID: PMC4363011, DOI: 10.1016/j.comppsych.2014.05.018.Peer-Reviewed Original ResearchConceptsAfrican American womenPsychological IPV severityPTSD symptom severityIntimate partner violencePTSD symptomsAmerican womenSymptom severityIPV severityHealth-compromising behaviorsPosttraumatic stress disorder (PTSD) symptomsSignificant positive associationHistory of DSHPartner violenceSymptomsCommunity womenSeverityWomenDisorder symptomsPositive associationUnderlying roleSixty participantsPresent studyDSH
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply