Xiaolong Tian

Associate Research Scientist in Genetics

About

Associate Research Scientist in Genetics

Frequent collaborators of Xiaolong Tian's published research.

3D multi-omics tumour atlases: from technology to biology and clinical translation
Liu M, Villazon J, Forjaz A, Tian X, Fan R, Wang S, Shi L, Wirtz D, Kiemen A. 3D multi-omics tumour atlases: from technology to biology and clinical translation. Nature Reviews Cancer 2026, 1-28. PMID: 42298141, DOI: 10.1038/s41568-026-00940-0.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
This study investigates 3D tumour atlases, showing how spatial multi-omics technologies uncover tumour evolution, aiding early cancer detection, risk stratification, and innovative treatment strategies.
Full Summary
Rational Design of Immune Gene Therapy Combinations via In Vivo CRISPR Activation Screen of Tumor Microenvironment Modulators.
Zhang F, Dong C, Chow R, Xin S, He E, Feng Y, Zhu L, Mirza D, Tian X, Yang L, Zhou L, Ling X, Han Q, Fan R, Chen S, Wang G. Rational Design of Immune Gene Therapy Combinations via In Vivo CRISPR Activation Screen of Tumor Microenvironment Modulators. Cancer Discovery 2026, 16: 1222-1244. PMID: 41747251, DOI: 10.1158/2159-8290.cd-25-0545.
Peer-Reviewed Original Research

Author Correction: Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy
Zhang F, Chow R, He E, Dong C, Xin S, Mirza D, Feng Y, Tian X, Verma N, Majety M, Zhang Y, Wang G, Chen S. Author Correction: Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy. Nature Biotechnology 2025, 43: 2068-2068. PMID: 39901026, DOI: 10.1038/s41587-025-02576-1.
Commentaries, Editorials and Letters
Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy
Zhang F, Chow R, He E, Dong C, Xin S, Mirza D, Feng Y, Tian X, Verma N, Majety M, Zhang Y, Wang G, Chen S. Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy. Nature Biotechnology 2025, 43: 2054-2067. PMID: 39820813, DOI: 10.1038/s41587-024-02535-2.
Peer-Reviewed Original Research

A Novel Targeted Long-read Sequencing Approach Boosts Transcriptomic Profiling
Tian X, Fan R. A Novel Targeted Long-read Sequencing Approach Boosts Transcriptomic Profiling. Genomics Proteomics & Bioinformatics 2024, 22: qzae090. PMID: 39724297, PMCID: PMC11802469, DOI: 10.1093/gpbjnl/qzae090.
Peer-Reviewed Original Research
Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues
Bai Z, Zhang D, Gao Y, Tao B, Zhang D, Bao S, Enninful A, Wang Y, Li H, Su G, Tian X, Zhang N, Xiao Y, Liu Y, Gerstein M, Li M, Xing Y, Lu J, Xu M, Fan R. Spatially exploring RNA biology in archival formalin-fixed paraffin-embedded tissues. Cell 2024, 187: 6760-6779.e24. PMID: 39353436, PMCID: PMC11568911, DOI: 10.1016/j.cell.2024.09.001.
Peer-Reviewed Original Research