Donna Spiegelman, ScD
Susan Dwight Bliss Professor of Biostatistics; Director, Center for Methods in Implementation and Prevention Science (CMIPS); Professor of Statistics and Data Science; Professor of Medicine (Cardiovascular Medicine); Assistant Director, Global Oncology, Yale Cancer CenterCards
About
Titles
Susan Dwight Bliss Professor of Biostatistics; Director, Center for Methods in Implementation and Prevention Science (CMIPS); Professor of Statistics and Data Science; Professor of Medicine (Cardiovascular Medicine); Assistant Director, Global Oncology, Yale Cancer Center
Biography
Donna Spiegelman was appointed the Susan Dwight Bliss Professor of Biostatistics at the Yale School of Public Health in 2018; she is also Professor of Statistics and Data Science at Yale University.
Dr. Spiegelman founded and directs the Yale Center for Methods in Implementation and Prevention Science (CMIPS) and she also leads the Global Oncology program at Yale Cancer Center.
As one of the few people in the world with a joint doctorate in biostatistics and epidemiology, she can freely speak the languages of both disciplines and switches between these two professional cultures, playing the role of interlocutor for each. She is interested in problems arising in epidemiology that require resolution, at least in part, through biostatistics.
The emerging field of implementation science is among Dr. Spiegelman's major areas of interest. This field examines barriers to the implementation of evidence-based interventions, as well as the factors that facilitate uptake of these tools. She founded CMIPS to develop tools for implementation science as well as to further the field's deployment to improve public health. The Center comprises 4 tenure-track full-time faculty members in biostatistics, social science and health economics; many additional faculty at YSPH and YSM; and PhD students, post-doctoral fellows, and master's degree students.
With colleagues at CMIPS, she studies the design and conduct of implementation studies and pragmatic trials. Topics include stepped-wedge and cluster randomized trials; positive spillover effects; two-stage designs; causal inference for large-scale public health interventions, including causal mediation analysis; correction for biases related to non-adherence and measurement error; and external generalizability; among others. CMIPS also focuses on developing methodsfor learning health care systems.
One of CMIPS' primary goals is to develop new statistical methods for implementation science. One such innovation is the Learn as You Go (LAGO) design, which allows researchers to repeatedly adapt ongoing trials in response to new trial data. Such designs help to prevent “failed trials." They can also optimize combination treatment regimens and inform cost-effective health promotion programs. Other biostatistical methods Dr. Spiegelman has developed relate to a wide range of topics, including meta-analysis, measurement error and misclassification, gene-environment and other interactions, smoothing, study design, and population-attributable risk.
Before coming to Yale, she served as professor, mentor, and expert statistician at the Harvard T.H. Chan School of Public Health for nearly 30 years.
Appointments
Biostatistics
ProfessorPrimaryStatistics
ProfessorSecondary
Other Departments & Organizations
- Biostatistics
- Biostatistics
- Cancer Prevention and Control
- Center for Interdisciplinary Research on AIDS
- Center for Methods in Implementation and Prevention Science (CMIPS)
- Global Mental Health Promotion Program
- Maternal and Child Health Promotion (MCHP) Program
- Statistics
- Yale Cancer Center
- Yale Institute for Global Health
- Yale School of Public Health
- Yale School of Public Health - NEW
- Yale-UPR Integrated HIV Basic and Clinical Sciences Initiative
- YSPH Global Health Concentration
Education & Training
- ScD
- Harvard School of Public Health, Biostatistics and Epidemiology (1989)
- MS
- Harvard School of Public Health, Biostatistics (1985)
- BA
- Brandeis University, Psychology (1977)
Research
Overview
Cancer epidemiology and prevention; Prevention science; cardiovascular disease epidemiology and prevention; HIV/AIDS epidemiology and prevention; maternal and child health promotion; mental health promotion;
Medical Research Interests
Public Health Interests
Academic Achievements & Community Involvement
News
News
- October 24, 2024
New Analytics Center for Cardiovascular Medicine
- September 03, 2024
Ariel Chao: a first in YSPH Biostatistics
- January 01, 2024
Spiegelman recognized as top female scientist for second consecutive year
- November 20, 2023
A New Approach for Evaluating Public Health Interventions