Alyssa Ann Grimshaw, MBA, MLIS, MPH
Biomedical Research and Methodology LibrarianCards
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Biomedical Research and Methodology Librarian
Biography
Alyssa Grimshaw is a Biomedical Research and Methodology Librarian.
She earned a post-master's certificate as an interprofessional informationist at Simmons University School of Library and Information Sciences. As an information expert, she collaborates on evidence synthesis and meta-research projects. Her research interests include reproducibility, reporting, and housing impacts on public health.
Alyssa provides in-depth reference, information, research and consultation services for clinical professionals and users in the health sciences community, including literature searches in support of systematic reviews, research, grants, clinical practice, animal use, teaching, and publishing.
For more information about me, please visit please page.
Departments & Organizations
- All Institutions
- Cushing/Whitney Medical Library
Education & Training
- MPH
- Dartmouth , Public Health (2024)
- MBA
- Southern New Hampshire University, Healthcare Management (2022)
- MLIS
- Drexel University, Library & Information Sciences (2017)
Research
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Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0003-3985-0056
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Craig Gunderson, MD, SFHM
James Farrell, MBChB, MD
Jan Philipp Bewersdorf, MD, FACP
Maximilian Stahl, MD
Alla Vash-Margita, MD, FACOG
Nikolai Podoltsev, MD, PhD
Systematic Reviews as Topic
Publications
2026
Association of Social Determinants of Health with Utilization of SGLT2 Inhibitors and GLP1 Receptor Agonists: A Systematic Review and Meta-Analysis
Shah N, Edjimbi J, Daou M, Grimshaw A, Gunderson C, Gupta S. Association of Social Determinants of Health with Utilization of SGLT2 Inhibitors and GLP1 Receptor Agonists: A Systematic Review and Meta-Analysis. Journal Of General Internal Medicine 2026, 1-14. PMID: 41838266, DOI: 10.1007/s11606-026-10178-z.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSocial determinants of healthSocial determinantsSocial determinants of health categoriesSystematic reviewHigh-deprivation neighborhoodsLow-SES patientsDeterminants of healthGLP-1RAOdds of utilizationMeta-analysisLower educational attainmentCross-sectional studyRisk of biasNeighborhood deprivationRandom-effects modelReceptor agonistsResultsTwenty-six studiesMethodsSix databasesPrivately insured patientsInsurance statusType 2 diabetesMetabolic riskGLP-1 receptor agonistsROBINS-I.Medicare AdvantageIncidence of acne in patients with inflammatory bowel disease treated with Janus kinase inhibitors: a systematic review and meta-analysis
Quraishi M, Alahmad M, Swaid T, Facciorusso A, Grimshaw A, Al-Bawardy B. Incidence of acne in patients with inflammatory bowel disease treated with Janus kinase inhibitors: a systematic review and meta-analysis. Inflammatory Bowel Diseases 2026, izag032. PMID: 41784155, DOI: 10.1093/ibd/izag032.Peer-Reviewed Original ResearchAltmetricConceptsIncidence of acnePatients treated with JAK inhibitorsInflammatory bowel diseaseJanus kinase inhibitorsInflammatory bowel disease patientsPooled incidenceRandomized Controlled TrialsAdverse eventsPediatric populationJAK inhibitorsPre-specified subgroup analysesEffective oral therapyInduction phaseJanus kinaseMeta-analysisInflammatory bowel disease populationSystematic reviewInflammatory bowel disease subtypePhase of treatmentOral therapySubgroup analysisKinase inhibitorsClinical subgroupsBowel diseaseRisk factorsEfficacy and safety of immunosuppressive therapy in connective tissue disease-related immune thrombocytopenia: a systematic review and meta-analysis.
Zhang Y, Yan X, Grimshaw A, Wang Y, Li M, Zeng X, Hsieh E, Jiang N. Efficacy and safety of immunosuppressive therapy in connective tissue disease-related immune thrombocytopenia: a systematic review and meta-analysis. Therapeutic Advances In Hematology 2026, 17: 20406207261422963. PMID: 41782905, PMCID: PMC12954039, DOI: 10.1177/20406207261422963.Peer-Reviewed Original ResearchConceptsConnective tissue diseaseImmune thrombocytopeniaImmunosuppressive therapyImmunosuppressive agentsSafety of immunosuppressive agentsGroup of autoimmune disordersSafety of immunosuppressive therapyComplete response rateSide effect incidenceNewcastle-Ottawa ScaleSystematic reviewMeta-analysis aimROBINS-I toolMantel-Haenszel formulaRandom-effects modelImmunosuppressive treatmentRelapse rateMulticenter studyTreatment regimenClinical featuresTherapy respondersAutoimmune disordersTissue diseaseSubgroup analysisSafety dataAssociation between baseline prostate MRI PI-RADS classification and risk of Gleason upgrade during active surveillance: a systematic review and meta-analysis
Smani S, Sohoni N, Miszczyk M, Fazekas T, Rajwa P, Grimshaw A, Sundaresan V, Lokeshwar S, Weinreb J, Sprenkle P, Cooperberg M, Seibert T, Shariat S, Catalona W, Leapman M. Association between baseline prostate MRI PI-RADS classification and risk of Gleason upgrade during active surveillance: a systematic review and meta-analysis. World Journal Of Urology 2026, 44: 169. PMID: 41691567, DOI: 10.1007/s00345-026-06278-4.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsPI-RADS 1PI-RADS 4Favorable risk prostate cancerRisk prostate cancerGleason grade groupPI-RADSProstate cancerMagnetic resonance imagingActive surveillanceGG upgradingRisk of biasDetection of high-grade prostate cancerRisk of Gleason upgradingHigh-grade prostate cancerProstate magnetic resonance imagingMagnetic resonance imaging findingsPI-RADS 3PI-RADS 5PI-RADS classificationPI-RADS scoreProstate Imaging-ReportingRisk of upgradeMeta-analysisRandom-effects meta-analysis modelROBINS-I toolAdvanced therapies for inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and meta-analysis
Li D, Chaar A, Arabi T, Quraishi M, Elgamal M, Alahdab F, Grimshaw A, Al-Bawardy B. Advanced therapies for inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and meta-analysis. Inflammatory Bowel Diseases 2026, izag001. PMID: 41677177, DOI: 10.1093/ibd/izag001.Peer-Reviewed Original ResearchConceptsPrimary sclerosing cholangitisInflammatory bowel diseaseIBD-PSCAdvanced therapiesClinical responseAnti-TNFSclerosing cholangitisMeta-analysisConcomitant inflammatory bowel diseaseAnti-tumor necrosis factorEndoscopic remission ratesInflammatory bowel disease associated with primary sclerosing cholangitisRates of overall infectionNon-anti-TNFNon-anti-TNF biologicsSystematic reviewRandom-effects modelClinical remissionEndoscopic remissionAcute cholangitisRemission rateProspective studySubgroup analysisNecrosis factorWeb of ScienceMass incarceration and its spillover effects: a scoping review of incarceration rates and health
Holaday L, Thomas K, King J, Grimshaw A, Simes J, Wang E. Mass incarceration and its spillover effects: a scoping review of incarceration rates and health. Social Science & Medicine 2026, 394: 118964. PMID: 41666809, DOI: 10.1016/j.socscimed.2026.118964.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSexually transmitted infectionsIncarceration ratesHealth outcomesSocial determinantsMass incarcerationChronic conditionsSocial determinants of healthOutcomes of physical healthGeographical levelsDeterminants of healthPoor health outcomesPopulation health effectsAdverse birth outcomesPositive independent associationSTI testingPopulation healthCrime dataPhysical healthPremature mortalityBirth outcomesStrong evidenceHousehold incarcerationMental healthEvidence of spilloversNeighborhood level
2025
Luspatercept for patients with lower-risk myelodysplastic syndromes/neoplasms: a systematic review and meta-analysis
Alhajahjeh A, Woite N, Rolles B, Stempel J, Mina A, Mendez L, Kewan T, Podoltsev N, Stahl M, Grimshaw A, Zeidan A, Bewersdorf J. Luspatercept for patients with lower-risk myelodysplastic syndromes/neoplasms: a systematic review and meta-analysis. Blood Advances 2025, 9: 6511-6523. PMID: 40966428, PMCID: PMC12767819, DOI: 10.1182/bloodadvances.2025017611.Peer-Reviewed Original ResearchCitationsAltmetricConceptsLower-risk myelodysplastic syndromesLow transfusion burdenTransfusion independenceTransfusion-DependentAdverse eventsTI rateSystematic reviewHematological improvement-erythroidWell-tolerated treatmentFrequent adverse eventsMeta-analysisSerious adverse eventsMeta-analysis aimTransfusion burdenMyelodysplastic syndromeFrontline settingPeripheral edemaSafety profileLuspaterceptPatientsAnemiaHigher RatesEfficacyReviewTransfusionDyadic Care Interventions and Outcomes for Mothers and Their Infants: A Scoping Review.
McAdow M, Martinez-Brockman J, Grimshaw A, Choy C, Rosenberg J. Dyadic Care Interventions and Outcomes for Mothers and Their Infants: A Scoping Review. 2025, 156 PMID: 41242520, PMCID: PMC12645281, DOI: 10.1542/peds.2025-073023.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsHome visitsCare modelCare interventionsImplementation outcomesScoping ReviewProvision of maternity careImplementation outcomes of acceptabilityMobility device interventionsInclusion criteriaMother–baby psychiatric unitsCommunity health workersMaternal mental healthYear of deliveryOutcomes of acceptabilityMedically trained personnelHealth workersPostpartum morbidityHealth professionalsPediatric appointmentsMaternity careBreastfeeding ratesMedical visitsMental healthStreamlined serviceComprehensive literature searchOritavancin for Treatment of Osteomyelitis: A Systematic Review and Meta‐Analysis of Observational Studies
Krsak M, Klimpl D, Mueller S, Morrisette T, Grimshaw A, Chastain D, Steuber T, Sah R, Henao‐Martinez A, Molina K. Oritavancin for Treatment of Osteomyelitis: A Systematic Review and Meta‐Analysis of Observational Studies. Pharmacotherapy The Journal Of Human Pharmacology And Drug Therapy 2025, 45: 754-763. PMID: 41224240, DOI: 10.1002/phar.70072.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMeta-analysis of observational studiesNewcastle-Ottawa ScaleObservational studyMeta-analysisDifficult-to-treat pathogensTherapeutic drug monitoring protocolSystematic reviewInfrequent dosing schedulesLong-acting lipoglycopeptidesClinical success rateProlonged antibiotic therapyResolution of infectionTreatment of osteomyelitisPotential treatment optionAdequate outcome assessmentAntibiotic therapyDosing scheduleParenteral therapySurgical debridementClinical successDosing strategiesTreatment optionsOritavancinBone infectionBiofilm-embedded pathogensMenin inhibitors for NPM1-mutated and KMT2A-rearranged relapsed/refractory acute myeloid leukemia (AML): A systematic review and meta-analysis
Beke K, Alhajahjeh A, Grimshaw A, Podoltsev N, Mendez L, Stahl M, Zeidan A, Bewersdorf J. Menin inhibitors for NPM1-mutated and KMT2A-rearranged relapsed/refractory acute myeloid leukemia (AML): A systematic review and meta-analysis. Blood 2025, 146: 5154-5154. DOI: 10.1182/blood-2025-5154.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaComposite complete responseOverall response rateNPM1 mutationsComplete responseAdverse eventsMenin inhibitorsStatistically significant differenceNucleophosmin 1Primary endpointMyeloid leukemiaAdult patientsPooled rateEndpoints of overall response rateMeta-analysisRates of grade 3Relapsed/Refractory Acute Myeloid LeukemiaAcute myeloid leukemia patientsSystematic reviewR/R AML patientsEarly mortality rateSignificant differenceAdult AML casesProspective cohort studyBlack quality assessment tool
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- November 17, 2025
Providing Dyadic Care to Mothers and Infants to Improve Health Outcomes
- April 24, 2024
Gender Gap in Promotion Within Academic Medicine
- February 14, 2024
Digital Health Tools Help Manage Hypertension for Populations Experiencing Health Disparities
- June 30, 2023
Pancreatic Cancer Risk Lower if Cysts Remain Stable for Five Years
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Yale Only Alyssa Ann Grimshaw, MBA, MLIS, MPH