Sarah Fineberg, MD, PhD
Assistant Professor of PsychiatryCards
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Clinical Neuroscience Research Unit
c/o CMHC, 34 Park St
New Haven, CT 06519
United States
About
Titles
Assistant Professor of Psychiatry
Biography
Dr. Fineberg holds an MD PhD from the University of Iowa, where she studied the molecular mechanisms that control early fate decisions for neural stem cells in mouse brain. She initially became interested in science as an undergraduate student at Oberlin College in physiology classes, where mechanism came alive in narratives about the evolutionary and individual history of the organism. She came to Yale in 2010 to pursue clinical and research training in psychiatry. Her current research engages both stories and brain-based mechanisms of mental illness, asking questions about how patient social experiences relate to neural circuits and learning mechanisms.
Dr. Fineberg has been awarded young investigator grants from the Brain and Behavior Research Foundation and the American Foundation for Suicide Prevention to pursue studies about social learning in Borderline Personality Disorder.
Appointments
Psychiatry
Assistant ProfessorPrimary
Other Departments & Organizations
- Center for Brain & Mind Health
- Damisah Lab
- Janeway Society
- Molecular Medicine, Pharmacology, and Physiology
- MR Center
- Neuroscience Research Training Program (NRTP)
- Program in Translational Biomedicine (PTB)
- Psychiatry
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)
- Yale Instruction/Investigation/Intervention in Emotional Lability and Dysregulation (YIELD)
- Yale Medicine
Education & Training
- PhD
- University of Iowa, Physiology and Biophysics (2010)
- MD
- University of Iowa (2010)
- BA
- Oberlin College, Biology (2000)
Research
Overview
Medical Research Interests
ORCID
0000-0001-6024-6721Fineberg Lab
The Fineberg Lab investigates the neurobiological mechanisms behind borderline personality disorder and related mental health conditions.
View Lab Website
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Philip Corlett, PhD
John Krystal, MD
Eli Neustadter
Matthew Steinfeld, PhD
Elizabeth Connors, PhD
D. S. Fahmeed Hyder, PhD
Borderline Personality Disorder
Ketamine
Publications
2024
Tell Me About Yourself: Analyzing Self-Referential Language Use in Borderline Personality Disorder
Welch J, Luo W, Ambroise K, Choi Y, Jones K, de Rouen A, Fineberg S. Tell Me About Yourself: Analyzing Self-Referential Language Use in Borderline Personality Disorder. Journal Of Psychiatric Research 2024, 180: 428-438. PMID: 39536504, DOI: 10.1016/j.jpsychires.2024.11.011.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderBorderline personality disorderTrauma-exposed controlsMarkers of distressPersonality disorderStress disorderNegative emotionsComorbid borderline personality disorderSelf-referenceHealthy controlsNon-psychiatric controlsNegative emotion wordsLexical markersLanguage useTrauma control groupComparing language usePhysical wordLanguage samplesEmotional wordsSelf-referential languageTone wordsIll sampleBetween-group differencesStudy 2Study 1
2023
Borderline personality disorder features are associated with inflexible social interpretations
Duda J, Fineberg S, Deng W, Ma Y, Everaert J, Cannon T, Joormann J. Borderline personality disorder features are associated with inflexible social interpretations. Journal Of Affective Disorders 2023, 348: 78-87. PMID: 38110156, DOI: 10.1016/j.jad.2023.12.036.Peer-Reviewed Original ResearchCitationsAltmetricModulation of Trust in Borderline Personality Disorder by Script-Based Imaginal Exposure to Betrayal.
Shapiro-Thompson R, Shah T, Yi C, Jackson N, Trujillo Diaz D, Fineberg S. Modulation of Trust in Borderline Personality Disorder by Script-Based Imaginal Exposure to Betrayal. Journal Of Personality Disorders 2023, 37: 508-524. PMID: 37903023, PMCID: PMC11002460, DOI: 10.1521/pedi.2023.37.5.508.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsThe association between evening social media use and delayed sleep may be causal: Suggestive evidence from 120 million Reddit timestamps
Meyerson W, Fineberg S, Andrade F, Corlett P, Gerstein M, Hoyle R. The association between evening social media use and delayed sleep may be causal: Suggestive evidence from 120 million Reddit timestamps. Sleep Medicine 2023, 107: 212-218. PMID: 37235891, DOI: 10.1016/j.sleep.2023.04.021.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSocial media useDelayed sleep onsetSelf-reported sleep patternsMedia useIndividual differencesDelayed sleepInsufficient sleepSleep onsetSleep patternsReddit usersSleepSocial media usageBedtimeSocial media usersAdditional supportOnset of sleepSocial mediaCausal effectMedia usageCausal relationshipPublic health officialsMedia usersPerceptionSuggestive evidenceReddit430. Calibrated fMRI Sensitive to Ketamine-Related Increases Throughout the Cortex
Driesen N, Herman P, Rowland M, Thompson G, Qiu M, He G, Criscuolo E, Fineberg S, Barron D, Helgeson L, Lacadie C, Chow R, Gueorguieva R, Straun T, Krystal J, Hyder F. 430. Calibrated fMRI Sensitive to Ketamine-Related Increases Throughout the Cortex. Biological Psychiatry 2023, 93: s268-s269. DOI: 10.1016/j.biopsych.2023.02.670.Peer-Reviewed Original ResearchA pilot randomized controlled trial of ketamine in Borderline Personality Disorder
Fineberg S, Choi E, Shapiro-Thompson R, Dhaliwal K, Neustadter E, Sakheim M, Null K, Trujillo-Diaz D, Rondeau J, Pittaro G, Peters J, Corlett P, Krystal J. A pilot randomized controlled trial of ketamine in Borderline Personality Disorder. Neuropsychopharmacology 2023, 48: 991-999. PMID: 36804489, PMCID: PMC10209175, DOI: 10.1038/s41386-023-01540-4.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBorderline personality disorderSecondary outcome measuresOutcome measuresSocio-occupational functioningSuicidal ideationPilot studyTrial of ketaminePersonality disorderInfusion of ketaminePrimary outcome measureEffects of ketamineMidazolam groupAdverse eventsKetamine groupClinical benefitMood symptomsKetamineFDA approvalDrug midazolamInfusionBPD symptomsLarger studyDepressed moodSymptomsChronic moodEstimation of Bedtimes of Reddit Users: Integrated Analysis of Time Stamps and Surveys
Meyerson W, Fineberg S, Song Y, Faber A, Ash G, Andrade F, Corlett P, Gerstein M, Hoyle R. Estimation of Bedtimes of Reddit Users: Integrated Analysis of Time Stamps and Surveys. JMIR Formative Research 2023, 7: e38112. PMID: 36649054, PMCID: PMC9890352, DOI: 10.2196/38112.Peer-Reviewed Original ResearchAltmetric
2022
Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial
Grilo CM, Lydecker JA, Fineberg SK, Moreno JO, Ivezaj V, Gueorguieva R. Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial. American Journal Of Psychiatry 2022, 179: 927-937. PMID: 36285406, PMCID: PMC9722598, DOI: 10.1176/appi.ajp.20220267.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsBehavioral weight loss therapyBinge-eating disorderPlacebo groupBupropion groupWeight lossRandomized double-blind placebo-controlled trialDouble-blind placebo-controlled trialLogistic regressionBinge-eating remissionPlacebo-controlled trialWeight loss therapyDouble-blind placeboSerious public health problemPublic health problemEvidence-based treatmentsRate of participantsBinge-eating frequencyBinge Eating DisorderMedical comorbiditiesRemission rateLoss therapyPercent weight lossMixed modelsFunctional impairmentSecondary measuresThe Stress and Resilience Town Hall: A systems response to support the health workforce during COVID-19 and beyond
Tebes JK, Awad MN, Connors EH, Fineberg SK, Gordon DM, Jordan A, Kravitz R, Li L, Ponce AN, Prabhu M, Rubman S, Silva MA, Steinfeld M, Tate DC, Xu K, Krystal JH. The Stress and Resilience Town Hall: A systems response to support the health workforce during COVID-19 and beyond. General Hospital Psychiatry 2022, 77: 80-87. PMID: 35569322, PMCID: PMC9033303, DOI: 10.1016/j.genhosppsych.2022.04.009.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsHealthcare workersHealth systemHealth workforceCOVID-19 pandemicHealth workforce needsMean attendancePost-traumatic stressCOVID-19Traumatic stressorsTypes of stressorsSustainable interventionsRigorous qualitative methodsInterventionPandemicSpecific stressorsStressorsWorkforce needsHospitalWorkersThe State of Overmedication in Borderline Personality Disorder: Interpersonal and Structural Factors
Shapiro-Thompson R, Fineberg SK. The State of Overmedication in Borderline Personality Disorder: Interpersonal and Structural Factors. Current Treatment Options In Psychiatry 2022, 9: 1-13. PMID: 36185615, PMCID: PMC9524237, DOI: 10.1007/s40501-021-00255-x.Peer-Reviewed Original ResearchCitationsAltmetricConceptsBorderline personality disorderPersonality disorderProspective treatment plansCommunication of patientsMedication useReviewThis review paperPractice guidelinesBPD patientsInpatient practiceSummaryMore researchPsychosocial interventionsMedicationsTreatment planMedical careBPD pathologyEarly detectionDiagnostic disclosureIndividual providersPatientsOvermedicationPrescribersCarePsychosocial modelDisordersIntervention
Clinical Trials
Current Trials
Social and Learning Behavior
HIC ID2000026215RolePrincipal InvestigatorPrimary Completion Date10/31/2029Recruiting ParticipantsGenderBothAge18 years - 45 years
Clinical Care
Overview
Clinical Specialties
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View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
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News
- October 26, 2022
People With Binge-eating Disorder Benefit From Specific Behavioral Therapy and Medication
- October 12, 2022
Fineberg, Le, Zaboski Awarded BBRF Young Investigator Grants
- January 30, 2022
Fineberg Awarded Yale Swebilius Pilot Research Award Program in Epilepsy Grant
- August 30, 2021
Yale Study Participants Release Songs Created as Part of Hallucination Research
Get In Touch
Contacts
Clinical Neuroscience Research Unit
c/o CMHC, 34 Park St
New Haven, CT 06519
United States