2020
A Pooled Analysis of Diffusion-Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage
Murthy SB, Cho SM, Gupta A, Shoamanesh A, Navi BB, Avadhani R, Gruber J, Li Y, Greige T, Lioutas VA, Norton C, Zhang C, Mandava P, Iadecola C, Falcone GJ, Sheth KN, Biffi A, Rosand J, Qureshi AI, Goldstein JN, Kidwell C, Awad I, Selim M, Hanley DF, Woo D, Kamel H, Ziai WC. A Pooled Analysis of Diffusion-Weighted Imaging Lesions in Patients With Acute Intracerebral Hemorrhage. JAMA Neurology 2020, 77: 1390-1397. PMID: 32687564, PMCID: PMC7372494, DOI: 10.1001/jamaneurol.2020.2349.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imaging lesionsModified Rankin scoreDWI lesionsImaging lesionsAcute intracerebral hemorrhageIntracerebral hemorrhageFunctional outcomeSubgroup analysisChronic cerebral small vessel diseaseAdmission systolic blood pressureCerebral small vessel diseaseMulticenter prospective studySystolic blood pressurePoor functional outcomeSmall vessel diseaseDeep intracerebral hemorrhageBaseline hematoma volumeIndividual patient dataMixed-effects logistic regressionMixed effects regression modelsAcute sequelaeHypertensive vasculopathyRankin scoreSecondary outcomesBlood pressure
2012
Confounding by Indication in Retrospective Studies of Intracerebral Hemorrhage: Antiepileptic Treatment and Mortality
Battey TW, Falcone GJ, Ayres AM, Schwab K, Viswanathan A, McNamara KA, DiPucchio ZY, Greenberg SM, Sheth KN, Goldstein JN, Rosand J. Confounding by Indication in Retrospective Studies of Intracerebral Hemorrhage: Antiepileptic Treatment and Mortality. Neurocritical Care 2012, 17: 361-366. PMID: 22965324, PMCID: PMC3707622, DOI: 10.1007/s12028-012-9776-z.Peer-Reviewed Original ResearchConceptsIntroductionIntracerebral hemorrhageAED treatmentAntiepileptic drugsCohort of patientsAntiepileptic treatmentRankin scoreICH locationIntracerebral hemorrhageRetrospective studyHemorrhage locationClinicians' decisionsResultsMultivariate analysisRetrospective analysisSupratentorial regionFatal diseaseConclusionThese resultsMortalityPatientsConflicting resultsTreatmentTreatment effectsHemorrhageCohortAssociationAdequate power