2023
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY
Green A, Curtis H, Higgins R, Nab L, Mahalingasivam V, Smith R, Mehrkar A, Inglesby P, Drysdale H, DeVito N, Croker R, Rentsch C, Bhaskaran K, Tazare J, Zheng B, Andrews C, Bacon S, Davy S, Dillingham I, Evans D, Fisher L, Hickman G, Hopcroft L, Hulme W, Massey J, MacDonald O, Morley J, Morton C, Park R, Walker A, Ward T, Wiedemann M, Bates C, Cockburn J, Parry J, Hester F, Harper S, Douglas I, Evans S, Goldacre B, Tomlinson L, MacKenna B. Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY. BMJ Medicine 2023, 2: e000276. PMID: 36936265, PMCID: PMC9951378, DOI: 10.1136/bmjmed-2022-000276.Peer-Reviewed Original ResearchDescriptive cohort studyHigh-risk groupSevere outcomesHigh riskCohort studyHome residentsRisk groupsAntiviral drugsCOVID-19Community settingsMonoclonal antibodiesCasirivimab/imdevimabLow treatment coverageNHS regionProportion of patientsCOVID-19 infectionRoutine clinical dataOpenSAFELY platformUnvaccinated patientsClinical characteristicsLiver diseaseClinical dataTreatment coverageEligibility criteriaPatients
2022
Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England: a descriptive cohort study within the OpenSAFELY platform
Collaborative T, Tazare J, Walker A, Tomlinson L, Hickman G, Rentsch C, Williamson E, Bhaskaran K, Evans D, Wing K, Mathur R, Wong A, Schultze A, Bacon S, Bates C, Morton C, Curtis H, Nightingale E, McDonald H, Mehrkar A, Inglesby P, Davy S, MacKenna B, Cockburn J, Hulme W, Warren-Gash C, Bhate K, Nitsch D, Powell E, Mulick A, Forbes H, Minassian C, Croker R, Parry J, Hester F, Harper S, Eggo R, Evans S, Smeeth L, Douglas I, Goldacre B. Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England: a descriptive cohort study within the OpenSAFELY platform. Wellcome Open Research 2022, 7: 142. PMID: 37362009, PMCID: PMC10285340, DOI: 10.12688/wellcomeopenres.17735.1.Peer-Reviewed Original ResearchDeep vein thrombosisCOVID-19 patientsHigh riskGeneral populationOpenSAFELY platformPulmonary embolismMyocardial infarctionCOVID-19Type 2 diabetes mellitus diagnosisSerious clinical outcomesPrimary care recordsDescriptive cohort studyCOVID-19 populationRisk of outcomesDiabetes mellitus diagnosisAge/sexMajority of outcomesPulmonary complicationsComparator cohortCohort studyIschemic strokeVein thrombosisHeart failureClinical outcomesAdverse outcomes