2021
Direct Attenuation Correction Using Deep Learning for Cardiac SPECT: A Feasibility Study
Yang J, Shi L, Wang R, Miller EJ, Sinusas AJ, Liu C, Gullberg GT, Seo Y. Direct Attenuation Correction Using Deep Learning for Cardiac SPECT: A Feasibility Study. Journal Of Nuclear Medicine 2021, 62: 1645-1652. PMID: 33637586, PMCID: PMC8612332, DOI: 10.2967/jnumed.120.256396.Peer-Reviewed Original Research
2018
Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose
Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.Peer-Reviewed Original ResearchConceptsPopulation-based input functionStandardized uptake valueImage-derived input functionLung nodulesClinical trialsTime-activity curvesLow-dose computed tomography (LDCT) screeningLung cancer mortality ratesIndeterminate lung nodulesComputed Tomography ScreeningF-FDG PETCancer mortality ratesStatic PET acquisitionVirtual clinical trialsScan durationTomography screeningFDG injectionPET scansMortality rateUptake valueAccurate diagnosisMalignant lung nodulesROC analysisPatient dataMalignant nodulesSimplified Quantification and Acquisition Protocol for 123I-MIBG Dynamic SPECT
Wu J, Gallezot JD, Lu Y, Ye Q, Liu H, Esserman DA, Kyriakides TC, Thorn S, Zonouz TH, Liu YH, Lampert R, Sinusas AJ, Carson RE, Liu C. Simplified Quantification and Acquisition Protocol for 123I-MIBG Dynamic SPECT. Journal Of Nuclear Medicine 2018, 59: 1574-1580. PMID: 29476001, DOI: 10.2967/jnumed.117.202143.Peer-Reviewed Original Research
2016
Quantitative Analysis of Dynamic 123I-mIBG SPECT Imaging Data in Healthy Humans with a Population-Based Metabolite Correction Method
Wu J, Lin SF, Gallezot JD, Chan C, Prasad R, Thorn S, Stacy MR, Huang Y, Zonouz TH, Liu YH, Lampert RJ, Carson RE, Sinusas AJ, Liu C. Quantitative Analysis of Dynamic 123I-mIBG SPECT Imaging Data in Healthy Humans with a Population-Based Metabolite Correction Method. Journal Of Nuclear Medicine 2016, 57: 1226-1232. PMID: 27081169, DOI: 10.2967/jnumed.115.171710.Peer-Reviewed Original Research3-IodobenzylguanidineAdultAgedAlgorithmsArtifactsComputer SimulationFemaleHeartHumansImage EnhancementImage Interpretation, Computer-AssistedMaleMiddle AgedModels, CardiovascularModels, StatisticalMyocardiumRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificityTissue DistributionTomography, Emission-Computed, Single-Photon
2010
Quiescent period respiratory gating for PET/CT
Liu C, Alessio A, Pierce L, Thielemans K, Wollenweber S, Ganin A, Kinahan P. Quiescent period respiratory gating for PET/CT. Medical Physics 2010, 37: 5037-5043. PMID: 20964223, PMCID: PMC2945743, DOI: 10.1118/1.3480508.Peer-Reviewed Original ResearchConceptsDisplacement signalQuiescent period gatingGating methodRespiratory motion compensationFraction of countsMotion compensationImproved signalSimulation dataNoise propertiesSignal histogramImage noiseMotion blurringImproved compromiseNoise increasesPET framesMaximum amplitudeComputer simulationsMotion artifactsReduced motionNoiseGatePhase gatingPatient respiratory tracesImage quality