2023
Insights from immunoproteomic profiling of a rejected full-face transplant
Lee C, Wang D, Kauke-Navarro M, Russell-Goldman E, Xu S, Mucciarone K, Sohrabi S, Lian C, Pomahac B, Murphy G. Insights from immunoproteomic profiling of a rejected full-face transplant. American Journal Of Transplantation 2023, 23: 1058-1061. PMID: 37037378, DOI: 10.1016/j.ajt.2023.04.008.Peer-Reviewed Original ResearchConceptsVascularized Composite AllograftsT cellsChronic rejectionCD8-positive T cellsEffector T cellsFull face transplantArteriosclerotic alterationsIntragraft arteriesVCA rejectionGraft arteryAccelerated arteriosclerosisRecipient originPunch biopsyAtherogenic responseComposite allograftsImmunoproteomic profilingDioxygenase 1Target endotheliumArteryEndotheliumProteomic profilingPathway componentsCellsRejectionAllografts
2018
Innovations in reconstructive microsurgery: Reconstructive transplantation
Kollar B, Tasigiorgos S, Dorante M, Carty M, Talbot S, Pomahac B. Innovations in reconstructive microsurgery: Reconstructive transplantation. Journal Of Surgical Oncology 2018, 118: 800-806. PMID: 30098294, DOI: 10.1002/jso.25147.Peer-Reviewed Original ResearchMeSH KeywordsForecastingGraft RejectionGraft SurvivalHumansImmunosuppressive AgentsMicrosurgeryOrgan TransplantationConceptsReconstructive transplantationViable reconstructive optionPediatric transplantsUpper extremityLower extremitiesAbdominal wallReconstructive optionsAdditional proceduresReconstructive microsurgeryTransplantationFace transplantTransplantPresent review articleExtremitiesReview articlePatientsUterusNeck
2017
Seasonal Variability Precipitating Hand Transplant Rejection?
Lopdrup R, Turk M, Win T, Marty F, Molway D, Tullius S, Pomahac B, Talbot S. Seasonal Variability Precipitating Hand Transplant Rejection? Transplantation 2017, 101: e313. PMID: 28930103, DOI: 10.1097/tp.0000000000001877.Peer-Reviewed Original ResearchOutcomes of Solid Organ Transplants After Simultaneous Solid Organ and Vascularized Composite Allograft Procurements
Aycart M, Alhefzi M, Sharma G, Krezdorn N, Bueno E, Talbot S, Carty M, Tullius S, Pomahac B. Outcomes of Solid Organ Transplants After Simultaneous Solid Organ and Vascularized Composite Allograft Procurements. Transplantation 2017, 101: 1381-1386. PMID: 27140518, PMCID: PMC6347371, DOI: 10.1097/tp.0000000000001262.Peer-Reviewed Original ResearchMeSH KeywordsAdultComposite Tissue AllograftsFacial TransplantationFemaleGraft SurvivalHumansMaleMiddle AgedOperative TimeOrgan TransplantationPostoperative ComplicationsRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTissue and Organ HarvestingTissue DonorsTreatment OutcomeUnited StatesYoung AdultConceptsGraft survival ratesSolid organsSurvival rateLiver recipientsTransplant recipientsAllograft procurementSolid organ allograftsSolid organ transplantsBrain-dead donorsLong-term outcomesShort-term resultsHeart recipientsIntraoperative parametersDonor surgeryOperative durationOrgan allograftsPostoperative outcomesScientific RegistryTransplantation outcomesPopulation of subjectsCase reportOperative characteristicsUnknown causeNationwide analysisOrgan transplantsReflections on a Decade of Face Transplantation
Giatsidis G, Sinha I, Pomahac B. Reflections on a Decade of Face Transplantation. Annals Of Surgery 2017, 265: 841-846. PMID: 28032849, DOI: 10.1097/sla.0000000000001760.Peer-Reviewed Original ResearchConceptsFace transplantationSci-fi novelsEthical discussionPersonal strugglesSocial beliefsFace transplantSocietal implicationsMedical discoveriesMedical innovationScienceFace restorationPublic opinionHigh-risk trajectoriesTodayLong wayMedical communityRegulatory frameworkBeliefsStruggleSocietyReflectionAnswersQuestionsDiscussionAnniversary
2016
Immunological Characteristics of a Patient With Belatacept‐Resistant Acute Rejection After Face Transplantation
Krezdorn N, Murakami N, Pomahac B, Riella L. Immunological Characteristics of a Patient With Belatacept‐Resistant Acute Rejection After Face Transplantation. American Journal Of Transplantation 2016, 16: 3305-3307. PMID: 27457067, PMCID: PMC5087655, DOI: 10.1111/ajt.13977.Peer-Reviewed Original ResearchCodominant Role of Interferon‐γ– and Interleukin‐17–Producing T Cells During Rejection in Full Facial Transplant Recipients
Borges T, O'Malley J, Wo L, Murakami N, Smith B, Azzi J, Tripathi S, Lane J, Bueno E, Clark R, Tullius S, Chandraker A, Lian C, Murphy G, Strom T, Pomahac B, Najafian N, Riella L. Codominant Role of Interferon‐γ– and Interleukin‐17–Producing T Cells During Rejection in Full Facial Transplant Recipients. American Journal Of Transplantation 2016, 16: 2158-2171. PMID: 26749226, PMCID: PMC4979599, DOI: 10.1111/ajt.13705.Peer-Reviewed Original ResearchConceptsDe novo donor-specific antibody developmentDe novo donor-specific antibodiesInterleukin-17-producing T cellsT helper 2 cell phenotypeFacial transplantationDonor-specific antibody developmentNovo donor-specific antibodiesChemotactic protein-1 levelsPeripheral blood mononuclear cellsAcute cellular rejectionAnti-HLA antibodiesDonor-specific antibodiesFollicular helper cellsImmune cell subsetsProtein-1 levelsBlood mononuclear cellsMedium-term outcomesSkin biopsy specimensFull facial transplantationCellular rejection processLife-changing procedureCellular rejectionCodominant roleDonor alloreactivityTransplant recipients
2012
Infections Following Facial Composite Tissue Allotransplantation—Single Center Experience and Review of the Literature
Knoll B, Hammond S, Koo S, Issa N, Tullius S, Baden L, Pomahac B, Marty F. Infections Following Facial Composite Tissue Allotransplantation—Single Center Experience and Review of the Literature. American Journal Of Transplantation 2012, 13: 770-779. PMID: 23279299, DOI: 10.1111/ajt.12013.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Infective AgentsCatheter-Related InfectionsCytomegalovirusCytomegalovirus InfectionsFaceFemaleGraft RejectionGraft SurvivalHumansMaleMiddle AgedPneumoniaPostoperative ComplicationsPrognosisSurgical Wound InfectionTissue TransplantationTransplantation, HomologousTrimethoprim, Sulfamethoxazole Drug CombinationConceptsFacial composite tissue allotransplantationCMV diseaseInfectious complicationsPosttransplant infectionsClostridium difficile-associated diarrheaDiscontinuation of prophylaxisEarly posttransplant infectionsSurgical site infectionDifficile-associated diarrheaCatheter-associated infectionsComposite tissue allotransplantationInvasive dermatophyte infectionAdditional prophylaxisBacterial parotitisPerioperative prophylaxisValganciclovir treatmentCenter experienceProphylaxis strategiesSite infectionPolymicrobial bacteremiaRecipient factorsTrimethoprim-sulfamethoxazoleMedical recordsDermatophyte infectionsProphylaxis
2010
Meshed Skin Grafts Placed Upside Down Can Take If Desiccation Is Prevented
Zuhaili B, Aflaki P, Koyama T, Fossum M, Reish R, Schmidt B, Pomahac B, Eriksson E. Meshed Skin Grafts Placed Upside Down Can Take If Desiccation Is Prevented. Plastic & Reconstructive Surgery 2010, 125: 855-865. PMID: 20195112, PMCID: PMC2848958, DOI: 10.1097/prs.0b013e3181ccdc42.Peer-Reviewed Original ResearchConceptsSkin graftsMeshed graftReepithelialization rateSplit-thickness skin graftMeshed skin graftAutologous split-thickness skin graftWound environmentFull-thickness woundsHistologic specimensAccelerated reepithelializationDay 4GraftHigh contraction rateWound contractionSheet graftsWound healingWoundsYorkshire pigsSignificant differencesSurvivalHealingRegular graftsReepithelializationContraction rateCurrent study